Detailed information
Bioinformatically predicted
Overview
| Name | comK/comK1 | Type | Regulator |
| Locus tag | QA593_RS09245 | Genome accession | NZ_CP121522 |
| Coordinates | 1968210..1968785 (-) | Length | 191 a.a. |
| NCBI ID | WP_001829272.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain 1DSE05 | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1931915..1967673 | 1968210..1968785 | flank | 537 |
Gene organization within MGE regions
Location: 1931915..1968785
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QA593_RS09020 | - | 1931915..1932835 (-) | 921 | WP_002501737.1 | peptidoglycan recognition family protein | - |
| QA593_RS09025 | - | 1932888..1933274 (-) | 387 | WP_002446772.1 | phage holin family protein | - |
| QA593_RS09030 | - | 1933276..1933557 (-) | 282 | WP_002501736.1 | hypothetical protein | - |
| QA593_RS09035 | - | 1933594..1934004 (-) | 411 | WP_002501735.1 | hypothetical protein | - |
| QA593_RS09040 | - | 1934025..1937480 (-) | 3456 | WP_002501734.1 | phage tail spike protein | - |
| QA593_RS09045 | - | 1937477..1938247 (-) | 771 | WP_049392193.1 | tail protein | - |
| QA593_RS09050 | - | 1938250..1942431 (-) | 4182 | WP_002501731.1 | phage tail tape measure protein | - |
| QA593_RS09055 | - | 1942495..1942695 (-) | 201 | WP_002501730.1 | hypothetical protein | - |
| QA593_RS09060 | - | 1942761..1943105 (-) | 345 | WP_002501729.1 | hypothetical protein | - |
| QA593_RS09065 | - | 1943129..1943833 (-) | 705 | WP_002484613.1 | hypothetical protein | - |
| QA593_RS09070 | - | 1943839..1944276 (-) | 438 | WP_002501727.1 | hypothetical protein | - |
| QA593_RS09075 | - | 1944276..1944614 (-) | 339 | WP_002501726.1 | hypothetical protein | - |
| QA593_RS09080 | - | 1944614..1944943 (-) | 330 | WP_002501725.1 | phage head closure protein | - |
| QA593_RS09085 | - | 1944915..1945223 (-) | 309 | WP_002484579.1 | phage head-tail connector protein | - |
| QA593_RS09090 | - | 1945250..1946407 (-) | 1158 | WP_002501724.1 | phage major capsid protein | - |
| QA593_RS09095 | - | 1946432..1947178 (-) | 747 | WP_002501723.1 | head maturation protease, ClpP-related | - |
| QA593_RS09100 | - | 1947178..1948314 (-) | 1137 | WP_002501722.1 | phage portal protein | - |
| QA593_RS09105 | - | 1948330..1949964 (-) | 1635 | WP_002501721.1 | terminase TerL endonuclease subunit | - |
| QA593_RS09110 | - | 1949948..1950286 (-) | 339 | WP_002501720.1 | hypothetical protein | - |
| QA593_RS09115 | - | 1950605..1950895 (-) | 291 | WP_002501719.1 | HNH endonuclease | - |
| QA593_RS09120 | - | 1951178..1951789 (-) | 612 | WP_002501718.1 | hypothetical protein | - |
| QA593_RS09125 | - | 1951993..1952484 (-) | 492 | WP_002501717.1 | sigma factor-like helix-turn-helix DNA-binding protein | - |
| QA593_RS09130 | - | 1952808..1954682 (-) | 1875 | WP_002501716.1 | DNA primase family protein | - |
| QA593_RS09135 | - | 1954712..1954906 (-) | 195 | WP_002501715.1 | hypothetical protein | - |
| QA593_RS09140 | - | 1954985..1955230 (-) | 246 | WP_002501714.1 | hypothetical protein | - |
| QA593_RS09145 | - | 1955302..1955517 (+) | 216 | WP_002491630.1 | hypothetical protein | - |
| QA593_RS09150 | - | 1955535..1955837 (-) | 303 | WP_002501713.1 | MazG-like family protein | - |
| QA593_RS09155 | - | 1955903..1956598 (+) | 696 | WP_002501712.1 | hypothetical protein | - |
| QA593_RS09160 | - | 1956606..1956995 (-) | 390 | WP_002501711.1 | hypothetical protein | - |
| QA593_RS09165 | - | 1957251..1958969 (-) | 1719 | WP_002501710.1 | hypothetical protein | - |
| QA593_RS09170 | - | 1959019..1959501 (-) | 483 | WP_002501709.1 | DUF669 domain-containing protein | - |
| QA593_RS09175 | - | 1959553..1959759 (-) | 207 | WP_002501708.1 | hypothetical protein | - |
| QA593_RS09180 | - | 1959778..1961589 (-) | 1812 | WP_002501707.1 | AAA family ATPase | - |
| QA593_RS09185 | - | 1961589..1961885 (-) | 297 | WP_002484599.1 | hypothetical protein | - |
| QA593_RS09190 | - | 1961878..1962195 (-) | 318 | WP_002501706.1 | hypothetical protein | - |
| QA593_RS09195 | - | 1962198..1963439 (-) | 1242 | WP_002501705.1 | SNF2-related protein | - |
| QA593_RS09200 | - | 1963587..1963781 (-) | 195 | WP_002491611.1 | DUF1270 family protein | - |
| QA593_RS09205 | - | 1964266..1964574 (-) | 309 | WP_002501703.1 | DUF771 domain-containing protein | - |
| QA593_RS09210 | - | 1964628..1964819 (-) | 192 | WP_002501702.1 | helix-turn-helix transcriptional regulator | - |
| QA593_RS09215 | - | 1964980..1965315 (+) | 336 | WP_002446811.1 | helix-turn-helix transcriptional regulator | - |
| QA593_RS09220 | - | 1965471..1965845 (+) | 375 | WP_002501701.1 | hypothetical protein | - |
| QA593_RS09225 | - | 1965858..1966532 (+) | 675 | WP_049392317.1 | Ltp family lipoprotein | - |
| QA593_RS09230 | - | 1966609..1967673 (+) | 1065 | WP_002491600.1 | site-specific integrase | - |
| QA593_RS09245 | comK/comK1 | 1968210..1968785 (-) | 576 | WP_001829272.1 | competence protein ComK | Regulator |
Sequence
Protein
Download Length: 191 a.a. Molecular weight: 22782.87 Da Isoelectric Point: 9.2887
>NTDB_id=812735 QA593_RS09245 WP_001829272.1 1968210..1968785(-) (comK/comK1) [Staphylococcus epidermidis strain 1DSE05]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN
Nucleotide
Download Length: 576 bp
>NTDB_id=812735 QA593_RS09245 WP_001829272.1 1968210..1968785(-) (comK/comK1) [Staphylococcus epidermidis strain 1DSE05]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comK/comK1 | Staphylococcus aureus MW2 |
76.757 |
96.859 |
0.743 |
| comK/comK1 | Staphylococcus aureus N315 |
76.757 |
96.859 |
0.743 |