Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   QA593_RS08055 Genome accession   NZ_CP121522
Coordinates   1723162..1724034 (-) Length   290 a.a.
NCBI ID   WP_002484839.1    Uniprot ID   A0A4Y7VXK4
Organism   Staphylococcus epidermidis strain 1DSE05     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1684702..1755576 1723162..1724034 within 0


Gene organization within MGE regions


Location: 1684702..1755576
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QA593_RS07910 - 1685742..1687013 (-) 1272 WP_002439538.1 pitrilysin family protein -
  QA593_RS07915 - 1687044..1687757 (-) 714 WP_002439536.1 GntR family transcriptional regulator -
  QA593_RS07920 - 1687760..1690153 (-) 2394 WP_002439534.1 DNA translocase FtsK -
  QA593_RS07925 - 1690419..1692092 (-) 1674 WP_002457357.1 ribonuclease J -
  QA593_RS07930 pnp 1692460..1694565 (-) 2106 WP_001832554.1 polyribonucleotide nucleotidyltransferase -
  QA593_RS07935 rpsO 1694697..1694966 (-) 270 WP_002439528.1 30S ribosomal protein S15 -
  QA593_RS07940 - 1695086..1696057 (-) 972 WP_001832563.1 bifunctional riboflavin kinase/FAD synthetase -
  QA593_RS07945 truB 1696073..1696990 (-) 918 WP_002456563.1 tRNA pseudouridine(55) synthase TruB -
  QA593_RS07950 rbfA 1697128..1697478 (-) 351 WP_001829509.1 30S ribosome-binding factor RbfA -
  QA593_RS07955 infB 1697781..1699943 (-) 2163 WP_002468903.1 translation initiation factor IF-2 -
  QA593_RS07960 - 1699948..1700265 (-) 318 WP_002439520.1 YlxQ family RNA-binding protein -
  QA593_RS07965 - 1700265..1700549 (-) 285 WP_001829465.1 YlxR family protein -
  QA593_RS07970 nusA 1700567..1701790 (-) 1224 WP_002456565.1 transcription termination factor NusA -
  QA593_RS07975 rimP 1701811..1702278 (-) 468 WP_002439519.1 ribosome maturation factor RimP -
  QA593_RS07980 - 1702457..1706767 (-) 4311 WP_002456566.1 PolC-type DNA polymerase III -
  QA593_RS07985 - 1707017..1708720 (-) 1704 WP_001829513.1 proline--tRNA ligase -
  QA593_RS07990 rseP 1708739..1710025 (-) 1287 WP_001829501.1 RIP metalloprotease RseP -
  QA593_RS07995 - 1710259..1711041 (-) 783 WP_001829499.1 phosphatidate cytidylyltransferase -
  QA593_RS08000 - 1711045..1711815 (-) 771 WP_001832561.1 isoprenyl transferase -
  QA593_RS08005 frr 1712036..1712590 (-) 555 WP_001829472.1 ribosome recycling factor -
  QA593_RS08010 pyrH 1712607..1713329 (-) 723 WP_002439511.1 UMP kinase -
  QA593_RS08015 tsf 1713470..1714348 (-) 879 WP_002439509.1 translation elongation factor Ts -
  QA593_RS08020 rpsB 1714500..1715288 (-) 789 WP_001832557.1 30S ribosomal protein S2 -
  QA593_RS08025 codY 1715651..1716421 (-) 771 WP_002439506.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  QA593_RS08030 hslU 1716445..1717848 (-) 1404 WP_001829474.1 ATP-dependent protease ATPase subunit HslU -
  QA593_RS08035 hslV 1717917..1718459 (-) 543 WP_001829498.1 ATP-dependent protease subunit HslV -
  QA593_RS08040 xerC 1718463..1719353 (-) 891 WP_002456225.1 tyrosine recombinase XerC -
  QA593_RS08045 trmFO 1719578..1720885 (-) 1308 WP_278276732.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  QA593_RS08050 topA 1720910..1722979 (-) 2070 WP_001829508.1 type I DNA topoisomerase -
  QA593_RS08055 dprA 1723162..1724034 (-) 873 WP_002484839.1 DNA-processing protein DprA Machinery gene
  QA593_RS08060 - 1724374..1724589 (-) 216 Protein_1554 transposase -
  QA593_RS08065 sucD 1724839..1725747 (-) 909 WP_002446283.1 succinate--CoA ligase subunit alpha -
  QA593_RS08070 sucC 1725769..1726935 (-) 1167 WP_002439496.1 ADP-forming succinate--CoA ligase subunit beta -
  QA593_RS08075 - 1727043..1727813 (-) 771 WP_001829514.1 ribonuclease HII -
  QA593_RS08080 ylqF 1727818..1728681 (-) 864 WP_002468554.1 ribosome biogenesis GTPase YlqF -
  QA593_RS08085 - 1729010..1731610 (+) 2601 WP_010959172.1 YfhO family protein -
  QA593_RS08090 - 1731603..1734206 (+) 2604 WP_020368058.1 YfhO family protein -
  QA593_RS08095 rplS 1734736..1735086 (-) 351 WP_002436293.1 50S ribosomal protein L19 -
  QA593_RS08100 trmD 1735192..1735929 (-) 738 WP_001829466.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  QA593_RS08105 rimM 1735929..1736432 (-) 504 WP_001832559.1 ribosome maturation factor RimM -
  QA593_RS08110 rpsP 1736559..1736834 (-) 276 WP_002439483.1 30S ribosomal protein S16 -
  QA593_RS08115 ffh 1737142..1738509 (-) 1368 WP_001830113.1 signal recognition particle protein -
  QA593_RS08120 - 1738540..1738872 (-) 333 WP_002457379.1 putative DNA-binding protein -
  QA593_RS08125 ftsY 1738874..1740100 (-) 1227 WP_001830080.1 signal recognition particle-docking protein FtsY -
  QA593_RS08130 smc 1740097..1743666 (-) 3570 WP_002502436.1 chromosome segregation protein SMC -
  QA593_RS08135 rnc 1743793..1744530 (-) 738 WP_002470220.1 ribonuclease III -
  QA593_RS08140 - 1744645..1744878 (-) 234 WP_001830184.1 acyl carrier protein -
  QA593_RS08145 fabG 1745105..1745839 (-) 735 WP_001830161.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  QA593_RS08150 fabD 1745832..1746758 (-) 927 WP_278276733.1 ACP S-malonyltransferase -
  QA593_RS08155 plsX 1746760..1747737 (-) 978 WP_001830112.1 phosphate acyltransferase PlsX -
  QA593_RS08160 fapR 1747739..1748299 (-) 561 WP_001830099.1 transcription factor FapR -
  QA593_RS08165 recG 1748458..1750506 (-) 2049 WP_020368084.1 ATP-dependent DNA helicase RecG -
  QA593_RS08170 fakA 1750710..1752368 (-) 1659 WP_002489351.1 fatty acid kinase catalytic subunit FakA -
  QA593_RS08175 - 1752383..1752757 (-) 375 WP_001830156.1 Asp23/Gls24 family envelope stress response protein -
  QA593_RS08180 rpmB 1753115..1753303 (+) 189 WP_001830107.1 50S ribosomal protein L28 -
  QA593_RS08185 - 1753386..1754021 (-) 636 WP_002489340.1 thiamine diphosphokinase -
  QA593_RS08190 rpe 1754026..1754670 (-) 645 WP_001830173.1 ribulose-phosphate 3-epimerase -
  QA593_RS08195 rsgA 1754671..1755546 (-) 876 WP_002456227.1 ribosome small subunit-dependent GTPase A -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33717.61 Da        Isoelectric Point: 9.3616

>NTDB_id=812734 QA593_RS08055 WP_002484839.1 1723162..1724034(-) (dprA) [Staphylococcus epidermidis strain 1DSE05]
MIQQTMLKLYWANFTTAQLHHLTSTYPDFLSENVFHQHDMIKRWLTERNSERLWNKYERFKELKLMDIIKEMKKANVSFT
TYFDDNYPSLCKEMYDYPYVIFYKGNPQFFNHSHSLAVIGSRNATQYTSQSLNYLFPSFRQLNMAIVSGLARGADSVAHQ
TALKYLLPTIGVLGFGHCYHYPKATLNLRTKVERNGLVISEYPPFSPISKHKFPERNRLISGLSRGVLITEAEERSGSQI
TIDCALEQNRNVYVLPGSMFNKMTKGNLRRINEGAQVVIDESSILYDYLF

Nucleotide


Download         Length: 873 bp        

>NTDB_id=812734 QA593_RS08055 WP_002484839.1 1723162..1724034(-) (dprA) [Staphylococcus epidermidis strain 1DSE05]
TTGATACAACAGACGATGTTAAAACTATATTGGGCAAATTTCACTACGGCACAACTTCATCATCTTACAAGTACATATCC
TGACTTTCTATCAGAAAACGTATTTCATCAACATGACATGATAAAAAGGTGGCTTACAGAGCGTAATTCTGAAAGGCTAT
GGAACAAATATGAACGTTTCAAAGAATTAAAGCTGATGGACATTATTAAAGAAATGAAAAAAGCAAATGTTAGTTTTACA
ACATACTTTGATGATAACTACCCTTCTCTTTGCAAAGAAATGTATGATTATCCTTATGTGATATTCTACAAAGGAAATCC
ACAGTTCTTTAATCATTCTCACTCTTTAGCTGTAATTGGCTCACGTAATGCCACACAATATACAAGTCAATCTTTAAACT
ATCTTTTTCCTTCATTTAGACAATTAAATATGGCGATTGTTTCTGGATTAGCGCGCGGTGCAGATAGTGTAGCACATCAA
ACCGCACTTAAATACCTATTACCAACTATTGGCGTACTTGGATTTGGCCATTGTTATCATTATCCTAAAGCAACCTTAAA
TTTAAGAACTAAAGTTGAAAGGAATGGCTTAGTGATAAGTGAATATCCACCATTTTCTCCTATAAGTAAGCATAAATTTC
CTGAAAGAAACAGGCTTATAAGTGGTCTGTCCAGAGGGGTACTTATAACTGAGGCTGAAGAAAGAAGTGGTAGTCAAATC
ACTATCGATTGTGCTTTAGAGCAAAATAGAAATGTTTATGTTCTACCTGGTTCAATGTTCAACAAAATGACTAAAGGTAA
TTTAAGAAGGATAAATGAAGGTGCTCAAGTTGTTATAGATGAAAGTAGTATATTATATGATTATCTATTTTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Y7VXK4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

56.944

99.31

0.566
  dprA Staphylococcus aureus N315

56.944

99.31

0.566