Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   QA588_RS08675 Genome accession   NZ_CP121507
Coordinates   1857912..1858784 (-) Length   290 a.a.
NCBI ID   WP_001829468.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain 23DSE01     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1819453..1890329 1857912..1858784 within 0


Gene organization within MGE regions


Location: 1819453..1890329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QA588_RS08530 - 1820493..1821764 (-) 1272 WP_002439538.1 pitrilysin family protein -
  QA588_RS08535 - 1821795..1822508 (-) 714 WP_002439536.1 GntR family transcriptional regulator -
  QA588_RS08540 - 1822511..1824904 (-) 2394 WP_002439534.1 DNA translocase FtsK -
  QA588_RS08545 - 1825170..1826843 (-) 1674 WP_002457357.1 ribonuclease J -
  QA588_RS08550 pnp 1827211..1829316 (-) 2106 WP_001832554.1 polyribonucleotide nucleotidyltransferase -
  QA588_RS08555 rpsO 1829448..1829717 (-) 270 WP_002439528.1 30S ribosomal protein S15 -
  QA588_RS08560 - 1829837..1830808 (-) 972 WP_001832563.1 bifunctional riboflavin kinase/FAD synthetase -
  QA588_RS08565 truB 1830824..1831741 (-) 918 WP_002456563.1 tRNA pseudouridine(55) synthase TruB -
  QA588_RS08570 rbfA 1831879..1832229 (-) 351 WP_001829509.1 30S ribosome-binding factor RbfA -
  QA588_RS08575 infB 1832532..1834694 (-) 2163 WP_002468903.1 translation initiation factor IF-2 -
  QA588_RS08580 - 1834699..1835016 (-) 318 WP_002439520.1 YlxQ family RNA-binding protein -
  QA588_RS08585 - 1835016..1835300 (-) 285 WP_001829465.1 YlxR family protein -
  QA588_RS08590 nusA 1835318..1836541 (-) 1224 WP_002456565.1 transcription termination factor NusA -
  QA588_RS08595 rimP 1836562..1837029 (-) 468 WP_002439519.1 ribosome maturation factor RimP -
  QA588_RS08600 - 1837208..1841518 (-) 4311 WP_002456566.1 PolC-type DNA polymerase III -
  QA588_RS08605 - 1841768..1843471 (-) 1704 WP_001829513.1 proline--tRNA ligase -
  QA588_RS08610 rseP 1843490..1844776 (-) 1287 WP_001829501.1 RIP metalloprotease RseP -
  QA588_RS08615 - 1845010..1845792 (-) 783 WP_001829499.1 phosphatidate cytidylyltransferase -
  QA588_RS08620 - 1845796..1846566 (-) 771 WP_001832561.1 isoprenyl transferase -
  QA588_RS08625 frr 1846787..1847341 (-) 555 WP_001829472.1 ribosome recycling factor -
  QA588_RS08630 pyrH 1847358..1848080 (-) 723 WP_002439511.1 UMP kinase -
  QA588_RS08635 tsf 1848221..1849099 (-) 879 WP_002439509.1 translation elongation factor Ts -
  QA588_RS08640 rpsB 1849251..1850039 (-) 789 WP_001832557.1 30S ribosomal protein S2 -
  QA588_RS08645 codY 1850398..1851171 (-) 774 WP_002446289.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  QA588_RS08650 hslU 1851195..1852598 (-) 1404 WP_002469380.1 ATP-dependent protease ATPase subunit HslU -
  QA588_RS08655 hslV 1852667..1853209 (-) 543 WP_001829498.1 ATP-dependent protease subunit HslV -
  QA588_RS08660 xerC 1853213..1854103 (-) 891 WP_002456225.1 tyrosine recombinase XerC -
  QA588_RS08665 trmFO 1854328..1855635 (-) 1308 WP_001832560.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  QA588_RS08670 topA 1855660..1857729 (-) 2070 WP_001829508.1 type I DNA topoisomerase -
  QA588_RS08675 dprA 1857912..1858784 (-) 873 WP_001829468.1 DNA-processing protein DprA Machinery gene
  QA588_RS08680 - 1859125..1859340 (-) 216 Protein_1660 IS200/IS605 family transposase -
  QA588_RS08685 sucD 1859590..1860498 (-) 909 WP_002446283.1 succinate--CoA ligase subunit alpha -
  QA588_RS08690 sucC 1860520..1861686 (-) 1167 WP_002456569.1 ADP-forming succinate--CoA ligase subunit beta -
  QA588_RS08695 - 1861794..1862564 (-) 771 WP_001829514.1 ribonuclease HII -
  QA588_RS08700 ylqF 1862569..1863432 (-) 864 WP_001829495.1 ribosome biogenesis GTPase YlqF -
  QA588_RS08705 - 1863761..1866361 (+) 2601 WP_278267382.1 YfhO family protein -
  QA588_RS08710 - 1866354..1868957 (+) 2604 WP_002456572.1 YfhO family protein -
  QA588_RS08715 rplS 1869487..1869837 (-) 351 WP_002436293.1 50S ribosomal protein L19 -
  QA588_RS08720 trmD 1869944..1870681 (-) 738 WP_001829466.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  QA588_RS08725 rimM 1870681..1871184 (-) 504 WP_001832559.1 ribosome maturation factor RimM -
  QA588_RS08730 rpsP 1871311..1871586 (-) 276 WP_002439483.1 30S ribosomal protein S16 -
  QA588_RS08735 ffh 1871894..1873261 (-) 1368 WP_001830113.1 signal recognition particle protein -
  QA588_RS08740 - 1873292..1873624 (-) 333 WP_002457379.1 putative DNA-binding protein -
  QA588_RS08745 ftsY 1873626..1874852 (-) 1227 WP_002456573.1 signal recognition particle-docking protein FtsY -
  QA588_RS08750 smc 1874849..1878418 (-) 3570 WP_278267393.1 chromosome segregation protein SMC -
  QA588_RS08755 rnc 1878545..1879282 (-) 738 WP_002456575.1 ribonuclease III -
  QA588_RS08760 - 1879397..1879630 (-) 234 WP_001830184.1 acyl carrier protein -
  QA588_RS08765 fabG 1879858..1880592 (-) 735 WP_001830161.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  QA588_RS08770 fabD 1880585..1881511 (-) 927 WP_002469385.1 ACP S-malonyltransferase -
  QA588_RS08775 plsX 1881513..1882490 (-) 978 WP_002469384.1 phosphate acyltransferase PlsX -
  QA588_RS08780 fapR 1882492..1883052 (-) 561 WP_001830099.1 transcription factor FapR -
  QA588_RS08785 recG 1883211..1885259 (-) 2049 WP_002456579.1 ATP-dependent DNA helicase RecG -
  QA588_RS08790 fakA 1885463..1887121 (-) 1659 WP_002456580.1 fatty acid kinase catalytic subunit FakA -
  QA588_RS08795 - 1887136..1887510 (-) 375 WP_001830156.1 Asp23/Gls24 family envelope stress response protein -
  QA588_RS08800 rpmB 1887868..1888056 (+) 189 WP_001830107.1 50S ribosomal protein L28 -
  QA588_RS08805 - 1888139..1888774 (-) 636 WP_001830164.1 thiamine diphosphokinase -
  QA588_RS08810 rpe 1888779..1889423 (-) 645 WP_002469381.1 ribulose-phosphate 3-epimerase -
  QA588_RS08815 rsgA 1889424..1890299 (-) 876 WP_002469378.1 ribosome small subunit-dependent GTPase A -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33726.62 Da        Isoelectric Point: 9.3618

>NTDB_id=812598 QA588_RS08675 WP_001829468.1 1857912..1858784(-) (dprA) [Staphylococcus epidermidis strain 23DSE01]
MIQHTMLKLYWANFTTAQLHHLTSTYPDFLSENVFHQHDMIKRWLTERNSERLWNKYERFKELKLMDIIKEMKKANVSFT
TYFDDNYPSLCKEMYDYPYVIFYKGNPQFFNHSHSLAVIGSRNATQYTSQSLNYLFPSFRQLNMAIVSGLARGADSVAHQ
TALKYLLPTIGVLGFGHCYHYPKATLNLRTKVERNGLVISEYPPFSPISKHKFPERNRLISGLSRGVLITEAEERSGSQI
TIDCALEQNRNVYVLPGSMFNKMTKGNLRRINEGAQVVIDESSILYDYLF

Nucleotide


Download         Length: 873 bp        

>NTDB_id=812598 QA588_RS08675 WP_001829468.1 1857912..1858784(-) (dprA) [Staphylococcus epidermidis strain 23DSE01]
TTGATACAACATACGATGTTAAAACTATATTGGGCAAATTTCACTACGGCACAACTTCATCATCTTACAAGTACATATCC
TGACTTTCTATCAGAAAACGTATTTCATCAACATGACATGATAAAAAGGTGGCTTACAGAGCGTAATTCTGAAAGGCTAT
GGAACAAATATGAACGTTTCAAAGAATTAAAGCTGATGGACATTATTAAAGAAATGAAAAAAGCAAATGTTAGTTTTACA
ACATACTTTGATGATAACTACCCTTCTCTTTGCAAAGAAATGTATGATTATCCTTATGTGATATTCTACAAAGGAAATCC
ACAGTTCTTTAATCATTCTCACTCTTTAGCTGTAATTGGCTCACGTAATGCCACACAATATACAAGTCAATCTTTAAACT
ATCTTTTTCCTTCATTTAGACAATTAAATATGGCGATTGTTTCTGGATTAGCGCGCGGTGCAGATAGTGTAGCACATCAA
ACCGCACTTAAATACCTATTACCAACTATTGGCGTACTTGGATTTGGCCATTGTTATCATTATCCTAAAGCAACCTTAAA
TTTAAGAACTAAAGTTGAAAGGAATGGCTTAGTGATAAGTGAATATCCACCATTTTCTCCTATAAGTAAGCATAAATTTC
CTGAAAGAAACAGGCTTATAAGTGGTCTGTCCAGAGGGGTACTTATAACTGAGGCTGAAGAAAGAAGTGGTAGTCAAATC
ACTATCGATTGTGCTTTAGAGCAAAATAGAAATGTTTATGTTCTACCTGGTTCAATGTTCAACAAAATGACTAAAGGTAA
TTTAAGAAGGATAAATGAAGGTGCTCAAGTTGTTATAGATGAAAGTAGTATATTATATGATTATCTATTTTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus N315

56.944

99.31

0.566
  dprA Staphylococcus aureus MW2

56.944

99.31

0.566