Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   QA611_RS08300 Genome accession   NZ_CP121497
Coordinates   1756792..1757664 (-) Length   290 a.a.
NCBI ID   WP_001829468.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain 24FSE04     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1718334..1791117 1756792..1757664 within 0


Gene organization within MGE regions


Location: 1718334..1791117
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QA611_RS08155 - 1719374..1720645 (-) 1272 WP_002439538.1 pitrilysin family protein -
  QA611_RS08160 - 1720676..1721389 (-) 714 WP_002439536.1 GntR family transcriptional regulator -
  QA611_RS08165 - 1721392..1723785 (-) 2394 WP_002439534.1 DNA translocase FtsK -
  QA611_RS08170 - 1724051..1725724 (-) 1674 WP_002457357.1 ribonuclease J -
  QA611_RS08175 pnp 1726092..1728197 (-) 2106 WP_001832554.1 polyribonucleotide nucleotidyltransferase -
  QA611_RS08180 rpsO 1728329..1728598 (-) 270 WP_002439528.1 30S ribosomal protein S15 -
  QA611_RS08185 - 1728718..1729689 (-) 972 WP_001832563.1 bifunctional riboflavin kinase/FAD synthetase -
  QA611_RS08190 truB 1729705..1730622 (-) 918 WP_002456563.1 tRNA pseudouridine(55) synthase TruB -
  QA611_RS08195 rbfA 1730760..1731110 (-) 351 WP_001829509.1 30S ribosome-binding factor RbfA -
  QA611_RS08200 infB 1731413..1733575 (-) 2163 WP_002468903.1 translation initiation factor IF-2 -
  QA611_RS08205 - 1733580..1733897 (-) 318 WP_002439520.1 YlxQ family RNA-binding protein -
  QA611_RS08210 - 1733897..1734181 (-) 285 WP_001829465.1 YlxR family protein -
  QA611_RS08215 nusA 1734199..1735422 (-) 1224 WP_002456565.1 transcription termination factor NusA -
  QA611_RS08220 rimP 1735443..1735910 (-) 468 WP_002439519.1 ribosome maturation factor RimP -
  QA611_RS08225 - 1736089..1740399 (-) 4311 WP_002456566.1 PolC-type DNA polymerase III -
  QA611_RS08230 - 1740649..1742352 (-) 1704 WP_001829513.1 proline--tRNA ligase -
  QA611_RS08235 rseP 1742371..1743657 (-) 1287 WP_001829501.1 RIP metalloprotease RseP -
  QA611_RS08240 - 1743891..1744673 (-) 783 WP_001829499.1 phosphatidate cytidylyltransferase -
  QA611_RS08245 - 1744677..1745447 (-) 771 WP_001832561.1 isoprenyl transferase -
  QA611_RS08250 frr 1745668..1746222 (-) 555 WP_001829472.1 ribosome recycling factor -
  QA611_RS08255 pyrH 1746239..1746961 (-) 723 WP_002439511.1 UMP kinase -
  QA611_RS08260 tsf 1747102..1747980 (-) 879 WP_002439509.1 translation elongation factor Ts -
  QA611_RS08265 rpsB 1748132..1748920 (-) 789 WP_278269714.1 30S ribosomal protein S2 -
  QA611_RS08270 codY 1749279..1750052 (-) 774 WP_002446289.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  QA611_RS08275 hslU 1750076..1751479 (-) 1404 WP_002469380.1 ATP-dependent protease ATPase subunit HslU -
  QA611_RS08280 hslV 1751548..1752090 (-) 543 WP_001829498.1 ATP-dependent protease subunit HslV -
  QA611_RS08285 xerC 1752094..1752984 (-) 891 WP_002456225.1 tyrosine recombinase XerC -
  QA611_RS08290 trmFO 1753208..1754515 (-) 1308 WP_001832560.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  QA611_RS08295 topA 1754540..1756609 (-) 2070 WP_001829508.1 type I DNA topoisomerase -
  QA611_RS08300 dprA 1756792..1757664 (-) 873 WP_001829468.1 DNA-processing protein DprA Machinery gene
  QA611_RS08305 - 1758005..1758220 (-) 216 Protein_1582 IS200/IS605 family transposase -
  QA611_RS08310 sucD 1758470..1759378 (-) 909 WP_002446283.1 succinate--CoA ligase subunit alpha -
  QA611_RS08315 sucC 1759400..1760566 (-) 1167 WP_002456569.1 ADP-forming succinate--CoA ligase subunit beta -
  QA611_RS08320 - 1760674..1761444 (-) 771 WP_001829514.1 ribonuclease HII -
  QA611_RS08325 ylqF 1761449..1762312 (-) 864 WP_001829495.1 ribosome biogenesis GTPase YlqF -
  QA611_RS08330 - 1762333..1762482 (-) 150 WP_162154119.1 hypothetical protein -
  QA611_RS08335 - 1762641..1765241 (+) 2601 WP_002456571.1 YfhO family protein -
  QA611_RS08340 - 1765234..1767837 (+) 2604 WP_002456572.1 YfhO family protein -
  QA611_RS08345 rplS 1768367..1768717 (-) 351 WP_002436293.1 50S ribosomal protein L19 -
  QA611_RS08350 trmD 1768823..1769560 (-) 738 WP_001829466.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  QA611_RS08355 rimM 1769560..1770063 (-) 504 WP_001832559.1 ribosome maturation factor RimM -
  QA611_RS08360 rpsP 1770190..1770465 (-) 276 WP_002439483.1 30S ribosomal protein S16 -
  QA611_RS08365 ffh 1770773..1772140 (-) 1368 WP_001830113.1 signal recognition particle protein -
  QA611_RS08370 - 1772171..1772503 (-) 333 WP_002457379.1 putative DNA-binding protein -
  QA611_RS08375 ftsY 1772505..1773731 (-) 1227 WP_002456573.1 signal recognition particle-docking protein FtsY -
  QA611_RS08380 smc 1773728..1777297 (-) 3570 WP_002497629.1 chromosome segregation protein SMC -
  QA611_RS08385 rnc 1777424..1778161 (-) 738 WP_002456575.1 ribonuclease III -
  QA611_RS08390 - 1778276..1778509 (-) 234 WP_001830184.1 acyl carrier protein -
  QA611_RS08395 fabG 1778737..1779471 (-) 735 WP_001830161.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  QA611_RS08400 fabD 1779464..1780390 (-) 927 WP_002469385.1 ACP S-malonyltransferase -
  QA611_RS08405 plsX 1780392..1781369 (-) 978 WP_002469384.1 phosphate acyltransferase PlsX -
  QA611_RS08410 fapR 1781371..1781931 (-) 561 WP_001830099.1 transcription factor FapR -
  QA611_RS08415 recG 1782090..1784138 (-) 2049 WP_002456579.1 ATP-dependent DNA helicase RecG -
  QA611_RS08420 fakA 1784342..1786000 (-) 1659 WP_002456580.1 fatty acid kinase catalytic subunit FakA -
  QA611_RS08425 - 1786015..1786389 (-) 375 WP_001830156.1 Asp23/Gls24 family envelope stress response protein -
  QA611_RS08430 rpmB 1786747..1786935 (+) 189 WP_001830107.1 50S ribosomal protein L28 -
  QA611_RS08435 - 1786925..1788652 (-) 1728 WP_278269719.1 IS1182-like element ISSep1 family transposase -
  QA611_RS08440 - 1788927..1789562 (-) 636 WP_001830164.1 thiamine diphosphokinase -
  QA611_RS08445 rpe 1789567..1790211 (-) 645 WP_001830173.1 ribulose-phosphate 3-epimerase -
  QA611_RS08450 rsgA 1790212..1791087 (-) 876 WP_002469378.1 ribosome small subunit-dependent GTPase A -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33726.62 Da        Isoelectric Point: 9.3618

>NTDB_id=812530 QA611_RS08300 WP_001829468.1 1756792..1757664(-) (dprA) [Staphylococcus epidermidis strain 24FSE04]
MIQHTMLKLYWANFTTAQLHHLTSTYPDFLSENVFHQHDMIKRWLTERNSERLWNKYERFKELKLMDIIKEMKKANVSFT
TYFDDNYPSLCKEMYDYPYVIFYKGNPQFFNHSHSLAVIGSRNATQYTSQSLNYLFPSFRQLNMAIVSGLARGADSVAHQ
TALKYLLPTIGVLGFGHCYHYPKATLNLRTKVERNGLVISEYPPFSPISKHKFPERNRLISGLSRGVLITEAEERSGSQI
TIDCALEQNRNVYVLPGSMFNKMTKGNLRRINEGAQVVIDESSILYDYLF

Nucleotide


Download         Length: 873 bp        

>NTDB_id=812530 QA611_RS08300 WP_001829468.1 1756792..1757664(-) (dprA) [Staphylococcus epidermidis strain 24FSE04]
TTGATACAACATACGATGTTAAAACTATATTGGGCAAATTTCACTACGGCACAACTTCATCATCTTACAAGTACATATCC
TGACTTTCTATCAGAAAACGTATTTCATCAACATGACATGATAAAAAGGTGGCTTACAGAGCGTAATTCTGAAAGGCTAT
GGAACAAATATGAACGTTTCAAAGAATTAAAGCTGATGGACATTATTAAAGAAATGAAAAAAGCAAATGTTAGTTTTACA
ACATACTTTGATGATAACTACCCTTCTCTTTGCAAAGAAATGTATGATTATCCTTATGTGATATTCTACAAAGGAAATCC
ACAGTTCTTTAATCATTCTCACTCTTTAGCTGTAATTGGCTCACGTAATGCCACACAATATACAAGTCAATCTTTAAACT
ATCTTTTTCCTTCATTTAGACAATTAAATATGGCGATTGTTTCTGGATTAGCGCGCGGTGCAGATAGTGTAGCACATCAA
ACCGCACTTAAATACCTATTACCAACTATTGGCGTACTTGGATTTGGCCATTGTTATCATTATCCTAAAGCAACCTTAAA
TTTAAGAACTAAAGTTGAAAGGAATGGCTTAGTGATAAGTGAATATCCACCATTTTCTCCTATAAGTAAGCATAAATTTC
CTGAAAGAAACAGGCTTATAAGTGGTCTGTCCAGAGGGGTACTTATAACTGAGGCTGAAGAAAGAAGTGGTAGTCAAATC
ACTATCGATTGTGCTTTAGAGCAAAATAGAAATGTTTATGTTCTACCTGGTTCAATGTTCAACAAAATGACTAAAGGTAA
TTTAAGAAGGATAAATGAAGGTGCTCAAGTTGTTATAGATGAAAGTAGTATATTATATGATTATCTATTTTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus N315

56.944

99.31

0.566
  dprA Staphylococcus aureus MW2

56.944

99.31

0.566