Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   QA590_RS04630 Genome accession   NZ_CP121483
Coordinates   1000327..1000902 (-) Length   191 a.a.
NCBI ID   WP_001829272.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain 32FSE07     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 993261..999926 1000327..1000902 flank 401


Gene organization within MGE regions


Location: 993261..1000902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QA590_RS04570 - 993273..993506 (-) 234 Protein_871 AAA family ATPase -
  QA590_RS04575 - 993878..994204 (+) 327 WP_278269417.1 hypothetical protein -
  QA590_RS04580 - 994335..994547 (-) 213 Protein_873 DUF771 domain-containing protein -
  QA590_RS04585 - 994551..995309 (-) 759 Protein_874 phage regulatory protein/antirepressor Ant -
  QA590_RS04590 - 995359..995913 (+) 555 WP_151515939.1 hypothetical protein -
  QA590_RS04595 - 996264..996455 (-) 192 WP_318835800.1 helix-turn-helix domain-containing protein -
  QA590_RS04600 - 996666..996998 (+) 333 WP_151515938.1 helix-turn-helix transcriptional regulator -
  QA590_RS04605 - 997004..997473 (+) 470 Protein_878 ImmA/IrrE family metallo-endopeptidase -
  QA590_RS04610 - 997489..998814 (+) 1326 WP_151515937.1 DUF4041 domain-containing protein -
  QA590_RS04615 - 998877..999926 (+) 1050 WP_151516768.1 site-specific integrase -
  QA590_RS04630 comK/comK1 1000327..1000902 (-) 576 WP_001829272.1 competence protein ComK Regulator

Sequence

Protein


Download         Length: 191 a.a.        Molecular weight: 22782.87 Da        Isoelectric Point: 9.2887

>NTDB_id=812454 QA590_RS04630 WP_001829272.1 1000327..1000902(-) (comK/comK1) [Staphylococcus epidermidis strain 32FSE07]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN

Nucleotide


Download         Length: 576 bp        

>NTDB_id=812454 QA590_RS04630 WP_001829272.1 1000327..1000902(-) (comK/comK1) [Staphylococcus epidermidis strain 32FSE07]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
GACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(7-158)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

76.757

96.859

0.743
  comK/comK1 Staphylococcus aureus N315

76.757

96.859

0.743