Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   P8P68_RS08835 Genome accession   NZ_CP121467
Coordinates   1828166..1828855 (+) Length   229 a.a.
NCBI ID   WP_000518004.1    Uniprot ID   K0ZJP2
Organism   Streptococcus sp. D7B5     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1823166..1833855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS08810 (P8P68_08810) gpsB 1823224..1823553 (+) 330 WP_000146523.1 cell division regulator GpsB -
  P8P68_RS08820 (P8P68_08820) - 1824039..1825196 (+) 1158 WP_000662905.1 class I SAM-dependent RNA methyltransferase -
  P8P68_RS08825 (P8P68_08825) - 1825209..1826654 (+) 1446 WP_000039240.1 cell division site-positioning protein MapZ family protein -
  P8P68_RS08830 (P8P68_08830) gndA 1826730..1828154 (+) 1425 WP_000158764.1 NADP-dependent phosphogluconate dehydrogenase -
  P8P68_RS08835 (P8P68_08835) covR 1828166..1828855 (+) 690 WP_000518004.1 response regulator transcription factor Regulator
  P8P68_RS08840 (P8P68_08840) cbpJ 1828955..1829959 (+) 1005 WP_008292544.1 choline-binding protein CbpJ -
  P8P68_RS08845 (P8P68_08845) mvk 1830077..1830955 (+) 879 WP_000163296.1 mevalonate kinase -
  P8P68_RS08850 (P8P68_08850) mvaD 1830937..1831890 (+) 954 WP_278275886.1 diphosphomevalonate decarboxylase -
  P8P68_RS08855 (P8P68_08855) - 1831877..1832884 (+) 1008 WP_278275887.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26813.96 Da        Isoelectric Point: 7.4140

>NTDB_id=812264 P8P68_RS08835 WP_000518004.1 1828166..1828855(+) (covR) [Streptococcus sp. D7B5]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDDLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=812264 P8P68_RS08835 WP_000518004.1 1828166..1828855(+) (covR) [Streptococcus sp. D7B5]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGGACAAAACCAGCCTCAGTGATTATGGTCTTA
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATGATCTAGTTGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATTTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTCTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGGTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K0ZJP2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467