Detailed information NTG0812263

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: RS157_RS18420
• Genome accession: NZ_CP135719
• Coordinates: 3825221..3828043 (-)
• Length: 940 a.a.
• NCBI ID: WP_315747377.1
• Uniprot ID: -
• Organism: Escherichia coli strain TUM1226
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3820221..3833043

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RS157_RS18395 (RS157_18395)	tyrB	3821267..3822460 (+)	1194	WP_000486939.1	aromatic amino acid transaminase	-
RS157_RS18400 (RS157_18400)	-	3822823..3823185 (-)	363	Protein_3595	hypothetical protein	-
RS157_RS18405 (RS157_18405)	aphA	3823586..3824299 (+)	714	WP_001226926.1	acid phosphatase AphA	-
RS157_RS18410 (RS157_18410)	yjbQ	3824410..3824826 (+)	417	WP_000270375.1	secondary thiamine-phosphate synthase enzyme YjbQ	-
RS157_RS18415 (RS157_18415)	yjbR	3824830..3825186 (+)	357	WP_000155657.1	MmcQ/YjbR family DNA-binding protein	-
RS157_RS18420 (RS157_18420)	uvrA	3825221..3828043 (-)	2823	WP_315747377.1	excinuclease ABC subunit UvrA	Machinery gene
RS157_RS18425 (RS157_18425)	ssb	3828298..3828834 (+)	537	WP_000168305.1	single-stranded DNA-binding protein SSB1	Machinery gene
RS157_RS18430 (RS157_18430)	yjcB	3828933..3829214 (-)	282	WP_001295689.1	YjcB family protein	-
RS157_RS18435 (RS157_18435)	pdeC	3829644..3831230 (+)	1587	WP_000019577.1	c-di-GMP phosphodiesterase PdeC	-
RS157_RS18440 (RS157_18440)	soxS	3831233..3831556 (-)	324	WP_000019358.1	superoxide response transcriptional regulator SoxS	-
RS157_RS18445 (RS157_18445)	soxR	3831642..3832106 (+)	465	WP_000412424.1	redox-sensitive transcriptional activator SoxR	-

Sequence

Protein

• Length: 940 a.a.
• Molecular weight: 103807.39 Da
• Isoelectric Point: 6.5109

>NTDB_id=812263 RS157_RS18420 WP_315747377.1 3825221..3828043(-) (uvrA) [Escherichia coli strain TUM1226]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLSQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGAHGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHTLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide

• Length: 2823 bp

>NTDB_id=812263 RS157_RS18420 WP_315747377.1 3825221..3828043(-) (uvrA) [Escherichia coli strain TUM1226]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAGCTCAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAAAAGCCGGACGTCGACCATATTGAGGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGTTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTTTGTTGTTCGCCCGCGTTGGCGAGCCGCGCTGTCCGGACCACGACGTCCCGCTGGCGGCGCAAACCGTCAGCC
AGATGGTGGATAACGTGCTGTCGCAGCCGGAAGGCAAGCGTCTGATGCTACTCGCGCCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAAAATCTGGCAAGCCAGGGTTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAACTGCAAAAGAAACATACCATTGAAGTGGTGGTTGATCGCTTCAAGGTGCGTGATGATCTTT
CCCAACGTCTTGCCGAGTCGTTTGAAACTGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTTGCGGATATGGACGACCCG
AAAGCGGAAGAGCTGCTGTTCTCCGCTAATTTCGCCTGCCCAATTTGCGGCTACAGTATGCGCGAGCTGGAGCCGCGACT
GTTTTCGTTTAACAACCCGGCAGGGGCCTGCCCGACCTGTGACGGCCTTGGCGTGCAGCAATATTTCGATCCTGACCGCG
TGATCCAGAATCCGGAACTGTCGCTGGCTGGCGGTGCGATCCGAGGCTGGGATCGCCGCAACTTCTATTACTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCGTGGGGCAGCCTGAGCGCGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAACATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACGGAATCCAGTGCGGTACGCGAAGAATTAGCCAAGTTT
ATCAGCAATCGCCCGTGCGCCAGCTGCGAAGGGACGCGTCTGCGTCGGGAAGCGCGCCATGTGTATGTCGAGAATACGCC
GCTGCCTGCTATCTCCGACATGAGCATCGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCAGGTCAGCGAGCTA
AGATTGCGGAAAAAATTCTTAAAGAGATTGGCGATCGCCTGAAATTCCTCGTTAACGTAGGCCTGAATTACCTGACACTT
TCCCGCTCGGCAGAGACACTTTCTGGCGGTGAAGCCCAGCGTATCCGTCTGGCGAGCCAGATTGGTGCGGGCCTGGTTGG
CGTTATGTACGTGCTGGACGAGCCGTCTATCGGCCTGCACCAGCGCGATAACGAGCGCCTGTTGGGTACGCTTATCCATC
TGCGCGATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCCGCTGACCATGTGATCGACATT
GGCCCGGGCGCAGGTGTACACGGCGGTGAAGTGGTCGCAGAAGGTCCACTGGAAGCGATTATGGCAGTGCCTGAGTCGTT
GACCGGGCAGTACATGAGCGGTAAACGCAAGATTGAAGTGCCGAAGAAACGCGTTCCGGCGAATCCGGAAAAAGTGCTGA
AGCTGACAGGCGCACACGGTAATAACCTGAAAGACGTGACGCTGACGCTGCCAGTCGGTCTGTTTACCTGCATCACAGGG
GTTTCAGGTTCCGGTAAATCGACACTGATTAACGACACACTGTTCCCGATTGCCCAACGCCAGTTGAATGGGGCGACCAT
CGCCGAACCGGCACCGTATCGCGATATTCAGGGGCTGGAGCATTTCGATAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCGCGTTCTAACCCGGCGACCTATACCGGCGTGTTTACGCCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGCGGTTATACGCCAGGACGTTTCAGCTTTAACGTCCGTGGCGGACGCTGCGAAGCCTGTCAGGGCGACGG
CGTGATCAAAGTGGAGATGCACTTCCTGCCGGATATCTACGTGCCGTGCGACCAGTGCAAAGGTAAACGCTATAACCGTG
AAACGCTGGAGATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCGGTGCCAGCTCTGGCGCGTAAGCTGCAAACGTTGATGGACGTTGGCCTGACGTACATTCGCCTCGGGCAGTCCGC
AACCACCCTTTCTGGTGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACACTGT
ATATTCTTGATGAGCCGACCACCGGTCTGCACTTCGCCGATATTCAGCAACTGCTCGACGTACTGCATACACTGCGCGAT
CAGGGCAATACCATTGTGGTGATTGAACACAATCTCGACGTGATCAAAACCGCTGACTGGATTGTCGACCTGGGACCGGA
AGGCGGCAGTGGTGGCGGCGAGATCCTCGTCTCCGGTACGCCAGAAACCGTCGCGGAGTGCGAAGCTTCGCATACGGCAC
GCTTCCTCAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (130-237)

• UvrA DNA-binding domain (UvrA_DNA-bind) (290-399)

• ABC transporter (ABC_tran) (806-860)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	57.264	100	0.574
uvrA	Streptococcus pneumoniae TIGR4	57.264	100	0.574
uvrA	Streptococcus pneumoniae D39	57.264	100	0.574