Detailed information NTG0812226

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: P8P68_RS05815
• Genome accession: NZ_CP121467
• Coordinates: 1208227..1209264 (-)
• Length: 345 a.a.
• NCBI ID: WP_000730765.1
• Uniprot ID: A0AAX3THV2
• Organism: Streptococcus sp. D7B5
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1203227..1214264

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P8P68_RS05790 (P8P68_05790)	-	1204121..1205452 (-)	1332	WP_070696073.1	hemolysin family protein	-
P8P68_RS05795 (P8P68_05795)	endA	1205588..1206412 (-)	825	WP_000358998.1	DNA/RNA non-specific endonuclease	Machinery gene
P8P68_RS05800 (P8P68_05800)	-	1206453..1206647 (-)	195	WP_000739701.1	DNA-directed RNA polymerase subunit beta	-
P8P68_RS05805 (P8P68_05805)	murA	1206634..1207917 (-)	1284	WP_278275754.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
P8P68_RS05810 (P8P68_05810)	-	1207941..1208171 (-)	231	WP_009013716.1	DUF1146 family protein	-
P8P68_RS05815 (P8P68_05815)	sepM	1208227..1209264 (-)	1038	WP_000730765.1	SepM family pheromone-processing serine protease	Regulator
P8P68_RS05820 (P8P68_05820)	coaD	1209248..1209736 (-)	489	WP_001280710.1	pantetheine-phosphate adenylyltransferase	-
P8P68_RS05825 (P8P68_05825)	rsmD	1209726..1210265 (-)	540	WP_278275755.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
P8P68_RS05830 (P8P68_05830)	asnA	1210330..1211322 (-)	993	WP_000747998.1	aspartate--ammonia ligase	-
P8P68_RS05835 (P8P68_05835)	-	1211432..1212115 (-)	684	WP_125389242.1	Bax inhibitor-1/YccA family protein	-
P8P68_RS05840 (P8P68_05840)	-	1212170..1212910 (-)	741	WP_278275756.1	RNA methyltransferase	-
P8P68_RS05845 (P8P68_05845)	-	1212944..1213222 (+)	279	WP_001174609.1	acylphosphatase	-
P8P68_RS05850 (P8P68_05850)	yidC	1213300..1214229 (+)	930	WP_049479479.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.77 Da
• Isoelectric Point: 5.5304

>NTDB_id=812226 P8P68_RS05815 WP_000730765.1 1208227..1209264(-) (sepM) [Streptococcus sp. D7B5]
MKKKTRWPLYVILALILTFLAFVVPLPYYIEVPGGAEDIRRVLKVNETEDTEAGAYQFVTVGIRHATLSHLVYAWLTPFT
DIRSAKETTGGSTDAEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYLGVYVLTVTDNSTFKGILNIADTVTAVNDKTF
DSSKDLVDYVNSQQLGDTVKVTYEEDGKVKSAEGKIITLENGKNGIGIGLIDRTEVTSDVPIRFSTAGIGGPSAGLMFSL
AIYTQIADPGLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVAASRQGANIFFAPDNPVTEEAKKADPNAKSNYETALEAAK
TIKTEMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=812226 P8P68_RS05815 WP_000730765.1 1208227..1209264(-) (sepM) [Streptococcus sp. D7B5]
ATGAAGAAAAAAACTAGATGGCCCTTATATGTCATCCTAGCACTAATATTGACGTTTTTAGCCTTTGTAGTACCTTTACC
ATACTACATAGAAGTTCCAGGTGGAGCGGAAGATATTCGTCGCGTTTTGAAAGTCAATGAAACAGAAGACACAGAAGCAG
GAGCTTACCAGTTTGTAACAGTCGGTATTCGACACGCAACCCTATCGCATCTTGTCTATGCTTGGTTAACGCCTTTCACA
GATATTAGAAGTGCCAAGGAGACTACGGGTGGCTCTACTGATGCAGAGTTTATGCGGATCAATCAGTTCTACATGCAAAC
TTCTCAAAACATGGCCAAGTATCAAGGATTGAAGACGGCTGGGAAAGATATTGAACTCAAGTATCTGGGAGTTTATGTCT
TGACCGTGACGGACAATTCAACTTTTAAGGGCATTCTGAACATTGCAGATACCGTGACGGCTGTTAATGACAAAACATTT
GACAGTTCAAAAGACTTGGTCGACTATGTCAACTCTCAACAATTAGGAGATACGGTCAAGGTAACCTATGAAGAAGACGG
AAAAGTCAAGTCTGCAGAAGGTAAAATTATCACTCTCGAAAACGGAAAAAACGGGATTGGAATTGGTTTGATTGACCGTA
CGGAAGTGACCAGTGACGTTCCAATTCGCTTTTCAACAGCTGGTATCGGCGGCCCAAGTGCCGGTCTCATGTTTAGTCTC
GCTATTTATACCCAGATAGCAGATCCAGGACTTCGTAATGGCCGCATCGTTGCGGGAACGGGAACTATTGATCGCGATGG
AAATGTTGGCGACATCGGTGGAATTGATAAAAAAGTAGTTGCAGCCTCTCGTCAGGGAGCCAACATCTTTTTTGCTCCTG
ACAATCCAGTCACCGAGGAAGCAAAAAAAGCAGATCCCAATGCGAAAAGCAACTATGAAACAGCCCTAGAAGCTGCTAAA
ACGATCAAAACAGAGATGAAAATCGTTCCCGTTAAGACTTTGCAGGATGCAATTGATTACCTTAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.234	99.13	0.597