Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   P8P68_RS05795 Genome accession   NZ_CP121467
Coordinates   1205588..1206412 (-) Length   274 a.a.
NCBI ID   WP_000358998.1    Uniprot ID   K0ZXQ9
Organism   Streptococcus sp. D7B5     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1200588..1211412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS05780 (P8P68_05780) amiA 1201640..1203619 (-) 1980 WP_070696075.1 peptide ABC transporter substrate-binding protein Regulator
  P8P68_RS05790 (P8P68_05790) - 1204121..1205452 (-) 1332 WP_070696073.1 hemolysin family protein -
  P8P68_RS05795 (P8P68_05795) endA 1205588..1206412 (-) 825 WP_000358998.1 DNA/RNA non-specific endonuclease Machinery gene
  P8P68_RS05800 (P8P68_05800) - 1206453..1206647 (-) 195 WP_000739701.1 DNA-directed RNA polymerase subunit beta -
  P8P68_RS05805 (P8P68_05805) murA 1206634..1207917 (-) 1284 WP_278275754.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  P8P68_RS05810 (P8P68_05810) - 1207941..1208171 (-) 231 WP_009013716.1 DUF1146 family protein -
  P8P68_RS05815 (P8P68_05815) sepM 1208227..1209264 (-) 1038 WP_000730765.1 SepM family pheromone-processing serine protease Regulator
  P8P68_RS05820 (P8P68_05820) coaD 1209248..1209736 (-) 489 WP_001280710.1 pantetheine-phosphate adenylyltransferase -
  P8P68_RS05825 (P8P68_05825) rsmD 1209726..1210265 (-) 540 WP_278275755.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  P8P68_RS05830 (P8P68_05830) asnA 1210330..1211322 (-) 993 WP_000747998.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29985.68 Da        Isoelectric Point: 9.8219

>NTDB_id=812225 P8P68_RS05795 WP_000358998.1 1205588..1206412(-) (endA) [Streptococcus sp. D7B5]
MDKKTRQALIGLLIFLLLAAGSYYIKQMQTAPNTPRTKVSQKKQASEAPSQELAESVLTELIKNQIKGGLEWNGAGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKALDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYRTGQVTVTD

Nucleotide


Download         Length: 825 bp        

>NTDB_id=812225 P8P68_RS05795 WP_000358998.1 1205588..1206412(-) (endA) [Streptococcus sp. D7B5]
ATGGATAAAAAAACAAGACAAGCTCTGATAGGGTTACTTATATTCTTACTCTTGGCTGCTGGAAGCTACTATATCAAGCA
GATGCAGACAGCGCCAAACACCCCTAGAACCAAGGTTAGTCAGAAAAAACAAGCTTCAGAAGCTCCCAGTCAGGAGCTGG
CTGAAAGTGTCTTAACTGAGTTAATCAAAAACCAAATCAAGGGGGGGCTTGAGTGGAATGGAGCAGGAGCCTTTATTGTC
AATGGCAATAAAACCAATCTAGATGCCAAGGTTTCTAGCAAACCCTATGCGGATAATAAAACAAAGACAGTGGGAAAAGA
AACAGTTCCAACGGTTGCCAATGCCATCTTATCCAAAGCGACTCGGCAGTATAAAAATCGTGAAGAGACTGGAAATGGCT
CCACCTCTTGGACGCCACCAGGATGGCATCAGGTCAAGAATCTAAAGGGGTCCTATACACATGCAGTTGATAGAGGACAC
CTGCTGGGTTATGCTTTGATAGGTGGTTTGGATGGTTTTGATGCCTCTACCAGCAATCCCAAGAATATTGCAGTTCAGAC
AGCTTGGGCTAACCAAGCGCAGGCTGAGGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGCCTTGGACC
AAAACAAGAGGGTCCGTTATCGCGTGACGCTCCACTATGCGACAAATGAGGACCTAGTTCCATCCGCTTCACAAATCGAA
GCCAAGTCTTCAGATGGCGAATTGGAATTCAATGTCCTAATCCCCAATGTTCAAAAGGGAATCCAGCTTGATTACCGAAC
AGGGCAAGTAACAGTGACGGACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K0ZXQ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

89.744

99.635

0.894
  endA Streptococcus pneumoniae D39

89.744

99.635

0.894
  endA Streptococcus pneumoniae R6

89.744

99.635

0.894
  endA Streptococcus pneumoniae TIGR4

89.744

99.635

0.894