Detailed information NTG0081144

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: HT073_RS08540
• Genome accession: NZ_AP023075
• Coordinates: 1638767..1639627 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain TUM16691
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1633767..1644627

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HT073_RS08525 (TUM16691C_16430)	dapD	1634277..1635098 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
HT073_RS08530 (TUM16691C_16440)	pgi	1635308..1636951 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
HT073_RS08535 (TUM16691C_16450)	pilG	1637461..1638693 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
HT073_RS08540 (TUM16691C_16460)	pilD	1638767..1639627 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
HT073_RS08545 (TUM16691C_16470)	coaE	1639624..1640256 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
HT073_RS08550	-	1640249..1640458 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
HT073_RS08555 (TUM16691C_16480)	pilF	1640544..1642220 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
HT073_RS08565 (TUM16691C_16490)	-	1642558..1643004 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
HT073_RS08570 (TUM16691C_16500)	-	1643008..1643982 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
HT073_RS08580 (TUM16691C_16510)	rplU	1644206..1644514 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=81144 HT073_RS08540 WP_003689814.1 1638767..1639627(+) (pilD) [Neisseria gonorrhoeae strain TUM16691]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=81144 HT073_RS08540 WP_003689814.1 1638767..1639627(+) (pilD) [Neisseria gonorrhoeae strain TUM16691]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441