Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   P8R99_RS11600 Genome accession   NZ_CP121160
Coordinates   2229961..2231187 (+) Length   408 a.a.
NCBI ID   WP_000918415.1    Uniprot ID   A0A0H1T4M5
Organism   Streptococcus agalactiae strain S5     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2224961..2236187
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8R99_RS11575 - 2225178..2225627 (-) 450 WP_001039194.1 DUF1836 domain-containing protein -
  P8R99_RS11580 - 2225719..2227002 (-) 1284 WP_278043302.1 hydroxymethylglutaryl-CoA reductase, degradative -
  P8R99_RS11585 - 2227004..2228176 (-) 1173 WP_079265808.1 hydroxymethylglutaryl-CoA synthase -
  P8R99_RS11590 - 2228330..2229169 (+) 840 WP_000158595.1 thymidylate synthase -
  P8R99_RS11595 - 2229249..2229743 (+) 495 WP_000166043.1 dihydrofolate reductase -
  P8R99_RS11600 clpX 2229961..2231187 (+) 1227 WP_000918415.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  P8R99_RS11605 yihA 2231198..2231794 (+) 597 WP_000796925.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  P8R99_RS11610 - 2231856..2232404 (-) 549 WP_000140664.1 TetR/AcrR family transcriptional regulator -
  P8R99_RS11615 - 2232496..2233146 (+) 651 WP_000645478.1 HXXEE domain-containing protein -
  P8R99_RS11620 - 2233158..2233808 (+) 651 WP_000120089.1 HXXEE domain-containing protein -
  P8R99_RS11625 - 2233938..2235314 (+) 1377 WP_278043303.1 amino acid permease -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44836.25 Da        Isoelectric Point: 4.4424

>NTDB_id=810701 P8R99_RS11600 WP_000918415.1 2229961..2231187(+) (clpX) [Streptococcus agalactiae strain S5]
MAGNRNNDMNVYCSFCGKSQDEVKKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLEILNQYVVGQDR
AKRALAVAVYNHYKRVSYTESSDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTKN
ILFIVGGAFDGIEDLVKQRLGEKVIGFGQTSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALELLTAEDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALLAIADKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGT
DKPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=810701 P8R99_RS11600 WP_000918415.1 2229961..2231187(+) (clpX) [Streptococcus agalactiae strain S5]
ATGGCTGGGAATCGTAATAACGATATGAATGTCTATTGTTCATTTTGTGGCAAAAGCCAAGATGAAGTAAAAAAAATTAT
TGCAGGTAATGGTGTTTTCATTTGTAATGAATGTGTGGCCTTATCACAAGAAATTATTAAGGAAGAATTAGCTGAGGAAG
TACTTGCTGATTTAGCAGAAGTACCAAAACCTAAGGAACTATTAGAAATATTAAATCAATATGTTGTAGGGCAAGATCGT
GCTAAACGTGCTTTAGCAGTTGCTGTCTACAATCATTACAAGCGTGTTAGTTATACCGAGAGTAGTGATGATGATGTAGA
TTTGCAAAAATCCAACATTTTGATGATTGGTCCAACTGGCTCAGGAAAAACCTTCTTAGCACAAACACTAGCTAAAAGCC
TTAATGTACCGTTTGCTATTGCAGATGCGACTTCATTGACCGAAGCAGGATACGTTGGAGAAGATGTTGAGAATATTCTT
CTTAAATTGATTCAAGCTGCTGATTATAATGTCGAACGTGCTGAGCGTGGTATTATCTACGTTGATGAAATAGATAAAAT
TGCTAAGAAAGGCGAAAATGTTTCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTATTG
AGGGTACGGTAGCAAGTGTTCCCCCACAGGGTGGGCGTAAACATCCTAACCAAGAAATGATTCAAATTAATACCAAGAAC
ATCCTTTTTATTGTCGGTGGTGCTTTTGATGGTATTGAAGACCTTGTGAAGCAACGTTTAGGCGAAAAAGTTATTGGTTT
TGGACAGACAAGCCGCAAAATTGATGACAACGCTTCTTATATGCAAGAGATAATTTCTGAGGATATTCAAAAGTTTGGAC
TGATTCCAGAGTTTATTGGCCGTTTACCAGTAGTTGCAGCGTTAGAACTTCTTACTGCAGAAGATCTGGTTCGTATTCTG
ACAGAACCACGCAATGCTTTGGTTAAACAATACCAAACCTTATTATCTTATGATGGTGTAGAATTGGAATTTGATCAGGA
TGCTCTATTAGCTATCGCTGATAAGGCTATCGAGCGCAAGACTGGTGCACGTGGTTTACGTTCTATTATTGAAGAAACGA
TGCTTGATATCATGTTTGAAATTCCAAGCCAAGAAGATGTAACAAAAGTTCGTATCACAAAGGCTGCTGTTGAGGGTACT
GACAAGCCTGTTTTAGAGACGGCTTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H1T4M5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

90.465

100

0.907
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.25

98.039

0.571