Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QN329_RS00115 Genome accession   NZ_CP135103
Coordinates   21803..22444 (-) Length   213 a.a.
NCBI ID   WP_000357891.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain HU36/21     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 16803..27444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QN329_RS00090 (QN329_00090) - 17203..18186 (-) 984 WP_000764456.1 sugar-binding transcriptional regulator -
  QN329_RS00095 (QN329_00095) - 18305..19060 (-) 756 WP_001080746.1 DeoR/GlpR family DNA-binding transcription regulator -
  QN329_RS00100 (QN329_00100) - 19181..19957 (+) 777 WP_000180537.1 glycyl-radical enzyme activating protein -
  QN329_RS00105 (QN329_00105) - 20003..20359 (-) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -
  QN329_RS00110 (QN329_00110) - 20361..21761 (-) 1401 WP_017647118.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  QN329_RS00115 (QN329_00115) vraR 21803..22444 (-) 642 WP_000357891.1 response regulator transcription factor Regulator
  QN329_RS00120 (QN329_00120) - 22437..23456 (-) 1020 WP_000716168.1 sensor histidine kinase -
  QN329_RS00125 (QN329_00125) liaF 23453..24148 (-) 696 WP_000714456.1 cell wall-active antibiotics response protein LiaF -
  QN329_RS00130 (QN329_00130) pknB 24307..26262 (-) 1956 WP_000614565.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  QN329_RS00135 (QN329_00135) - 26262..26999 (-) 738 WP_000406234.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23634.35 Da        Isoelectric Point: 5.0159

>NTDB_id=809892 QN329_RS00115 WP_000357891.1 21803..22444(-) (vraR) [Streptococcus agalactiae strain HU36/21]
MDKIKIVLVDDHEMVRLGLKSFLNLQADVEVIGEASNGLEGIKKALELRPDVVVMDLVMPEMDGVEATLALLKDWPEAAI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIRKVARGEQAIENEVDKKIKAHDKCPALHEGLTARERDILNLLA
KGYDNQRIADELFISLKTVKTHVSNILGKLNVADRTQAVVYAFQHHLVPQDDE

Nucleotide


Download         Length: 642 bp        

>NTDB_id=809892 QN329_RS00115 WP_000357891.1 21803..22444(-) (vraR) [Streptococcus agalactiae strain HU36/21]
ATGGATAAAATAAAAATTGTACTTGTTGATGACCATGAGATGGTTCGTCTCGGTTTAAAAAGTTTTTTAAACTTACAAGC
TGATGTTGAAGTAATAGGTGAAGCCTCAAATGGTTTAGAAGGCATAAAAAAAGCACTGGAGTTACGTCCAGATGTTGTTG
TTATGGATTTAGTAATGCCTGAAATGGACGGTGTAGAAGCAACCTTAGCATTATTGAAGGATTGGCCAGAAGCTGCTATT
TTAGTCTTAACATCTTACTTGGACAATGAAAAAATTTACCCTGTTATTGAAGCAGGTGCCAAAGGCTATATGTTAAAGAC
CTCAAGTGCAGCAGAGATTCTTAATGCCATTCGTAAAGTTGCAAGGGGAGAACAAGCTATTGAAAATGAAGTAGATAAGA
AAATTAAGGCTCATGATAAATGTCCAGCTTTACATGAGGGCTTAACAGCAAGGGAACGTGATATCCTTAATTTATTAGCC
AAAGGTTATGACAATCAAAGGATTGCTGATGAATTATTTATCTCGTTAAAGACTGTTAAAACTCATGTTTCTAATATTTT
GGGAAAACTAAATGTAGCAGATCGAACTCAAGCGGTTGTCTATGCTTTCCAACACCATTTGGTACCACAAGATGATGAAT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

96.714

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.394