Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   QN328_RS00560 Genome accession   NZ_CP135102
Coordinates   103281..104255 (+) Length   324 a.a.
NCBI ID   WP_410530968.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain HU32/21     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98281..109255
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QN328_RS00520 (QN328_00520) - 98971..99336 (+) 366 WP_000285373.1 DUF1033 family protein -
  QN328_RS00525 (QN328_00525) comGA 99509..100480 (+) 972 WP_000250805.1 competence type IV pilus ATPase ComGA Machinery gene
  QN328_RS00530 (QN328_00530) comGB 100374..101417 (+) 1044 WP_223295889.1 competence type IV pilus assembly protein ComGB Machinery gene
  QN328_RS00535 (QN328_00535) comGC/cglC 101414..101743 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  QN328_RS00540 (QN328_00540) comGD 101718..102131 (+) 414 WP_017646959.1 competence type IV pilus minor pilin ComGD Machinery gene
  QN328_RS00545 (QN328_00545) comGE 102103..102402 (+) 300 WP_025195478.1 competence type IV pilus minor pilin ComGE Machinery gene
  QN328_RS00550 (QN328_00550) comGF 102356..102817 (+) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF Machinery gene
  QN328_RS00555 (QN328_00555) comGG 102795..103166 (+) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG Machinery gene
  QN328_RS00560 (QN328_00560) comGH 103281..104255 (+) 975 WP_410530968.1 class I SAM-dependent methyltransferase Machinery gene
  QN328_RS00565 (QN328_00565) - 104287..105480 (+) 1194 WP_000047534.1 acetate kinase -
  QN328_RS00570 (QN328_00570) - 105632..105838 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  QN328_RS00575 (QN328_00575) - 105897..106034 (+) 138 WP_001865900.1 hypothetical protein -
  QN328_RS00580 (QN328_00580) - 106075..106530 (+) 456 WP_000905673.1 hypothetical protein -
  QN328_RS00585 (QN328_00585) - 106599..107264 (+) 666 WP_000008113.1 CPBP family intramembrane glutamic endopeptidase -
  QN328_RS00590 (QN328_00590) proC 107285..108055 (-) 771 WP_001865901.1 pyrroline-5-carboxylate reductase -
  QN328_RS00595 (QN328_00595) pepA 108125..109192 (-) 1068 WP_001281323.1 glutamyl aminopeptidase -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 37060.05 Da        Isoelectric Point: 4.5224

>NTDB_id=809801 QN328_RS00560 WP_410530968.1 103281..104255(+) (comGH) [Streptococcus agalactiae strain HU32/21]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADIIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK

Nucleotide


Download         Length: 975 bp        

>NTDB_id=809801 QN328_RS00560 WP_410530968.1 103281..104255(+) (comGH) [Streptococcus agalactiae strain HU32/21]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATATCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(70-303)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA159

67.619

97.222

0.657
  comGH Streptococcus mutans UA140

67.619

97.222

0.657