Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LLHP_RS04405 Genome accession   NZ_CP120921
Coordinates   866357..867829 (+) Length   490 a.a.
NCBI ID   WP_032950293.1    Uniprot ID   A0A1V0PFR7
Organism   Lactococcus cremoris subsp. cremoris HP     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 861357..872829
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLHP_RS04375 (LLHP_04395) - 861800..862648 (+) 849 WP_231099822.1 CHAP domain-containing protein -
  LLHP_RS04380 (LLHP_04400) - 862885..863247 (+) 363 Protein_852 TIGR02328 family protein -
  LLHP_RS04385 (LLHP_04405) - 863571..863816 (+) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LLHP_RS04390 (LLHP_04410) - 863921..864811 (-) 891 WP_396424831.1 IS982 family transposase -
  LLHP_RS04395 (LLHP_04415) - 864965..865495 (+) 531 WP_011834860.1 DUF177 domain-containing protein -
  LLHP_RS04400 (LLHP_04420) covR 865652..866344 (+) 693 WP_011676631.1 response regulator transcription factor Regulator
  LLHP_RS04405 (LLHP_04425) covS 866357..867829 (+) 1473 WP_032950293.1 HAMP domain-containing histidine kinase Regulator
  LLHP_RS04410 (LLHP_04430) - 868015..869256 (+) 1242 WP_015082643.1 ammonium transporter -
  LLHP_RS04415 (LLHP_04435) - 869340..869681 (+) 342 WP_011676628.1 P-II family nitrogen regulator -
  LLHP_RS04420 (LLHP_04440) murD 869850..871199 (+) 1350 WP_032950291.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLHP_RS04425 (LLHP_04445) murG 871442..872515 (+) 1074 WP_011676626.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55890.81 Da        Isoelectric Point: 4.7784

>NTDB_id=809333 LLHP_RS04405 WP_032950293.1 866357..867829(+) (covS) [Lactococcus cremoris subsp. cremoris HP]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRRDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAKEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKI

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=809333 LLHP_RS04405 WP_032950293.1 866357..867829(+) (covS) [Lactococcus cremoris subsp. cremoris HP]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACGTGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCAAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTGGCTCGTTTAGCCGAAAATTATCAAGGAGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATATGA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

HAMP domain (HAMP)

(208-258)

ArlS sensor domain (ArlS_N)

(54-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0PFR7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.49

100

0.945