Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   LLHP_RS03285 Genome accession   NZ_CP120921
Coordinates   644396..645097 (+) Length   233 a.a.
NCBI ID   WP_011676802.1    Uniprot ID   A0A0M2ZUZ8
Organism   Lactococcus cremoris subsp. cremoris HP     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 639396..650097
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLHP_RS03270 (LLHP_03285) - 641794..642702 (+) 909 WP_014572147.1 diacylglycerol kinase family protein -
  LLHP_RS03275 (LLHP_03290) - 642848..643534 (+) 687 WP_014572148.1 amino acid ABC transporter permease -
  LLHP_RS03280 (LLHP_03295) - 643534..644268 (+) 735 WP_011676803.1 amino acid ABC transporter ATP-binding protein -
  LLHP_RS03285 (LLHP_03300) mecA 644396..645097 (+) 702 WP_011676802.1 adaptor protein MecA Regulator
  LLHP_RS03290 (LLHP_03305) - 645100..646425 (+) 1326 WP_032950445.1 glycosyltransferase family 4 protein -
  LLHP_RS03295 (LLHP_03310) sufC 646601..647371 (+) 771 WP_011676800.1 Fe-S cluster assembly ATPase SufC -
  LLHP_RS03300 (LLHP_03315) sufD 647511..648767 (+) 1257 WP_032950449.1 Fe-S cluster assembly protein SufD -
  LLHP_RS03305 (LLHP_03320) - 648767..649987 (+) 1221 WP_021213770.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27046.46 Da        Isoelectric Point: 4.1802

>NTDB_id=809323 LLHP_RS03285 WP_011676802.1 644396..645097(+) (mecA) [Lactococcus cremoris subsp. cremoris HP]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGAKKEEAEHEPDFIYYSIRYDDMMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKAKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLITTRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=809323 LLHP_RS03285 WP_011676802.1 644396..645097(+) (mecA) [Lactococcus cremoris subsp. cremoris HP]
ATGAAGTATGAGGATATAAATGAAAACACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAGTT
ATCTGACTTTTTTGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTAGTTGATGAACTTGGCTTAGAAAATCGTT
TTGGAAATGTAGGGATGTTAACTTTCCAAATTCAACCCTTCCCACAAGGCGTCCATATGATTGTTCATGAAGAAGCAATG
TTGGGTGAAGGCGGAGAGATTCCAGATGATCCTGAAGAATTTGAAGAATTAATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGACTTGGTTTACCAGGGGCTAAAAAAGAAG
AAGCCGAACATGAGCCAGACTTTATATACTACTCTATTCGTTATGATGACATGATGTCTGTCTTGACTGGAATAAAAAAT
GTGAAATTCGCAGATGAAGAGTCAGAATTTTATCGTTATGATGGTAATTTTTATCTTGTTGTTTTAGATAATCAAAAAGC
AAAAGGTAAAATGCATGTTGAAAGCACACGTTCACGGATGATGGAATATGGTGAAGCGACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGCCTAATCACAACGCGTGCTTTAGACGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M2ZUZ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

100

100

1
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

96.567

100

0.966