Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RMQ61_RS02490 Genome accession   NZ_CP135090
Coordinates   490918..491559 (+) Length   213 a.a.
NCBI ID   WP_024413700.1    Uniprot ID   -
Organism   Streptococcus suis strain ID48908     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 485918..496559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMQ61_RS02470 (RMQ61_02470) - 486219..486956 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  RMQ61_RS02475 (RMQ61_02475) pknB 486956..488614 (+) 1659 Protein_449 Stk1 family PASTA domain-containing Ser/Thr kinase -
  RMQ61_RS11760 - 488735..488950 (+) 216 Protein_450 serine/threonine protein kinase -
  RMQ61_RS02480 (RMQ61_02480) liaF 489274..489933 (+) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  RMQ61_RS02485 (RMQ61_02485) - 489930..490946 (+) 1017 WP_024417018.1 sensor histidine kinase -
  RMQ61_RS02490 (RMQ61_02490) vraR 490918..491559 (+) 642 WP_024413700.1 response regulator transcription factor Regulator
  RMQ61_RS02495 (RMQ61_02495) - 491609..493009 (+) 1401 WP_029173958.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  RMQ61_RS02500 (RMQ61_02500) - 493011..493382 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  RMQ61_RS02505 (RMQ61_02505) cysK 493409..494335 (-) 927 WP_002937015.1 cysteine synthase A -
  RMQ61_RS02510 (RMQ61_02510) - 494425..495057 (-) 633 WP_014636235.1 YigZ family protein -
  RMQ61_RS02515 (RMQ61_02515) comFA/cflA 495114..496406 (+) 1293 WP_012774986.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23818.41 Da        Isoelectric Point: 4.8970

>NTDB_id=809012 RMQ61_RS02490 WP_024413700.1 490918..491559(+) (vraR) [Streptococcus suis strain ID48908]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILVAIRKVAIGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=809012 RMQ61_RS02490 WP_024413700.1 490918..491559(+) (vraR) [Streptococcus suis strain ID48908]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGCCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCGTTAGAGGTTAAACCTGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGGTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGTAGCCATCCGCAAGGTAGCTATTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACACATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413