Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   P4831_RS09425 Genome accession   NZ_CP120842
Coordinates   1874657..1875358 (-) Length   233 a.a.
NCBI ID   WP_004255173.1    Uniprot ID   S6FFV7
Organism   Lactococcus lactis strain ZFM559     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1869657..1880358
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P4831_RS09405 - 1869767..1870984 (-) 1218 WP_023164477.1 cysteine desulfurase -
  P4831_RS09410 sufD 1870984..1872240 (-) 1257 WP_023164478.1 Fe-S cluster assembly protein SufD -
  P4831_RS09415 sufC 1872378..1873148 (-) 771 WP_023164479.1 Fe-S cluster assembly ATPase SufC -
  P4831_RS09420 - 1873323..1874654 (-) 1332 WP_023164480.1 MraY family glycosyltransferase -
  P4831_RS09425 mecA 1874657..1875358 (-) 702 WP_004255173.1 adaptor protein MecA Regulator
  P4831_RS09430 - 1875488..1876222 (-) 735 WP_004255171.1 amino acid ABC transporter ATP-binding protein -
  P4831_RS09435 - 1876222..1876908 (-) 687 WP_004255158.1 amino acid ABC transporter permease -
  P4831_RS09440 - 1877056..1877964 (-) 909 WP_023164481.1 diacylglycerol kinase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27077.46 Da        Isoelectric Point: 4.1246

>NTDB_id=808785 P4831_RS09425 WP_004255173.1 1874657..1875358(-) (mecA) [Lactococcus lactis strain ZFM559]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=808785 P4831_RS09425 WP_004255173.1 1874657..1875358(-) (mecA) [Lactococcus lactis strain ZFM559]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTCGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FFV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.571

100

0.996
  mecA Lactococcus lactis subsp. cremoris KW2

96.996

100

0.97