Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   RPQ07_RS16570 Genome accession   NZ_CP135086
Coordinates   3684584..3685708 (+) Length   374 a.a.
NCBI ID   WP_313944917.1    Uniprot ID   A0ACC6PYI5
Organism   Streptomyces sp. AM8-1-1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3679584..3690708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RPQ07_RS16560 (RPQ07_16560) - 3681185..3682849 (-) 1665 WP_313944915.1 BACON domain-containing protein -
  RPQ07_RS16565 (RPQ07_16565) radA/sms 3683085..3684539 (+) 1455 WP_313944916.1 DNA repair protein RadA Machinery gene
  RPQ07_RS16570 (RPQ07_16570) disA 3684584..3685708 (+) 1125 WP_313944917.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  RPQ07_RS16575 (RPQ07_16575) - 3685778..3686605 (-) 828 WP_313944918.1 hypothetical protein -
  RPQ07_RS16580 (RPQ07_16580) - 3687183..3688088 (+) 906 WP_313944919.1 A/G-specific adenine glycosylase -
  RPQ07_RS16585 (RPQ07_16585) - 3688273..3688878 (+) 606 WP_313944920.1 SigE family RNA polymerase sigma factor -
  RPQ07_RS16590 (RPQ07_16590) - 3688866..3689537 (+) 672 WP_313944921.1 hypothetical protein -
  RPQ07_RS16595 (RPQ07_16595) cseB 3689547..3690254 (+) 708 WP_313944922.1 two-component system response regulator CseB -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40387.25 Da        Isoelectric Point: 4.8731

>NTDB_id=808755 RPQ07_RS16570 WP_313944917.1 3684584..3685708(+) (disA) [Streptomyces sp. AM8-1-1]
MAANDRAAAPGKSGGGSGNEALIRAALSAVAPGQALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSRQCGFPVVSVSQSMRLIALYVDGERRVLEESAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALFELDSLTHTELLELPIVARALGYSGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=808755 RPQ07_RS16570 WP_313944917.1 3684584..3685708(+) (disA) [Streptomyces sp. AM8-1-1]
GTGGCAGCCAACGACCGGGCAGCAGCACCCGGAAAGTCCGGCGGAGGCTCCGGCAACGAAGCACTGATCCGCGCCGCCCT
GAGCGCGGTGGCGCCGGGCCAGGCCCTGCGCGACGGCCTGGAGCGGATCCTCCGCGGCAACACCGGCGGCCTGATCGTCC
TCGGTATGGACAAAACGGTCGAATCGATGTGCACCGGCGGCTTCGTGCTGGATGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTGGACGGCGCGCTGATCCTCGACAAGGACATCACCAAGATCCTCCGGGCCGGTGTGCAGCTGGTTCC
GGACGCGTCCATCCCCACCGAGGAGACCGGCACCCGCCACCGCACGGCGGACCGGGTGTCGCGTCAGTGCGGCTTCCCCG
TGGTGTCCGTGTCGCAGTCCATGCGCCTCATCGCGCTGTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAGTCGGCCGCG
ATCCTGTCCCGCGCGAACCAGGCCCTCGCGACCCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTCGCGGGCACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCACGGCCGTGGCCCAGCGCCTGGAGATGGTGCGACGGATCG
CCACCGAGATCGCCGAGTACGTGGTCGAGTTGGGCACCGACGGACGGCTGCTCTCCCTCCAGCTCGACGAGTTGATCGCG
GGCGTCGAGCCCGAGCGCGAGCTGGTCGTGCGTGACTATGTGCCCGAGCCCACCGCAAAGCGGTCCCGTACGGTCGACGA
GGCCCTGTTCGAGCTGGACTCCCTGACCCACACGGAACTACTGGAACTACCCATAGTGGCCAGGGCTTTGGGCTACAGCG
GCTCGCCCGAGACCCTCGACTCCGCGGTCTCCCCGCGCGGCTACCGGCTGCTGGCGAAGGTGCCGAGACTGCCGGGCGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGCGGGCTGCAGAAGCTGCTCGCGGCGAGCGTCGACGACCTTCAGACGGTCGA
CGGTGTGGGCGAGGCGCGCGCACGCAGCGTCCGCGAGGGCCTGTCACGGCTCGCGGAGTCCTCGATTCTCGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.429

96.524

0.438