Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RPQ02_RS21455 Genome accession   NZ_CP135085
Coordinates   4783308..4783970 (+) Length   220 a.a.
NCBI ID   WP_313938445.1    Uniprot ID   -
Organism   Streptomyces sp. AM2-3-1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4778308..4788970
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RPQ02_RS21435 (RPQ02_21435) - 4778796..4779644 (+) 849 WP_313938441.1 tryptophan 2,3-dioxygenase family protein -
  RPQ02_RS21440 (RPQ02_21440) kynU 4779637..4780875 (+) 1239 WP_313938442.1 kynureninase -
  RPQ02_RS21445 (RPQ02_21445) - 4780984..4781859 (+) 876 WP_313938443.1 alpha/beta hydrolase family protein -
  RPQ02_RS21450 (RPQ02_21450) - 4781992..4783311 (+) 1320 WP_313938444.1 sensor histidine kinase -
  RPQ02_RS21455 (RPQ02_21455) vraR 4783308..4783970 (+) 663 WP_313938445.1 response regulator transcription factor Regulator
  RPQ02_RS21460 (RPQ02_21460) - 4784009..4785238 (+) 1230 WP_313938446.1 cytochrome P450 -
  RPQ02_RS21465 (RPQ02_21465) - 4785455..4787050 (-) 1596 WP_313938447.1 ABC transporter permease -
  RPQ02_RS21470 (RPQ02_21470) - 4787047..4787970 (-) 924 WP_030977738.1 ABC transporter ATP-binding protein -
  RPQ02_RS21475 (RPQ02_21475) - 4788084..4788617 (+) 534 WP_389741320.1 GbsR/MarR family transcriptional regulator -
  RPQ02_RS21480 (RPQ02_21480) - 4788662..4788934 (-) 273 WP_313938448.1 DUF1876 domain-containing protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23549.33 Da        Isoelectric Point: 4.9350

>NTDB_id=808672 RPQ02_RS21455 WP_313938445.1 4783308..4783970(+) (vraR) [Streptomyces sp. AM2-3-1]
MNDIRVLIVDDQMMVREGFSVLLGAMPGIEVVGEAVDGRQAIAQAAALRPDVVLMDIRMPELNGIEATREIVANDAAAKV
LVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVAAGEALLAPTVTRRLITEFSRLAGAPRPPALARIGDLTER
ETEVLVLIAQGLSNAEIASHLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPA

Nucleotide


Download         Length: 663 bp        

>NTDB_id=808672 RPQ02_RS21455 WP_313938445.1 4783308..4783970(+) (vraR) [Streptomyces sp. AM2-3-1]
ATGAACGACATCCGTGTCCTGATCGTCGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTACTCCTGGGGGCGATGCC
GGGCATCGAGGTCGTCGGCGAGGCGGTCGACGGCCGGCAGGCCATCGCCCAGGCCGCCGCGCTGCGGCCCGACGTGGTGC
TGATGGACATCCGGATGCCGGAGCTCAACGGCATCGAGGCGACCCGTGAGATCGTCGCGAACGACGCGGCCGCCAAGGTG
CTCGTGCTGACCACGTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCCGGGGCGTCAGGGTTCCTGCTGAAGGA
CGCCTCCGCCCGGCAGCTCGCCGACGGGGTACGGGTGGTGGCGGCCGGGGAGGCGCTGCTGGCGCCGACCGTCACAAGGC
GGTTGATCACCGAGTTCTCCCGGCTCGCGGGGGCCCCGCGGCCGCCCGCGCTCGCCCGGATCGGCGATCTGACGGAGCGC
GAGACGGAGGTGCTCGTCCTCATCGCCCAGGGCCTGTCGAACGCGGAGATCGCCTCGCATCTGGTGGTCGCCGAGTCCAC
CATCAAGACGCATGTGAGCCGAATCCTGGTGAAGCTGGGGCTGCGGGACCGTACGCAGGCGGCGGTGTTCGCGTACGAGG
CGAGGCTGGTCACCCCGGCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-115)

Bacterial regulatory proteins, luxR family (GerE)

(157-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.393

97.273

0.432
  degU Bacillus subtilis subsp. subtilis str. 168

42.727

100

0.427