Detailed information NTG0080815

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: OW489_RS07905
• Genome accession: NZ_AP026446
• Coordinates: 1643950..1646532 (+)
• Length: 860 a.a.
• NCBI ID: WP_120856479.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain CHC155
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1638950..1651532

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OW489_RS07875 (CHC155_15390)	-	1640481..1641646 (-)	1166	Protein_1542	DHH family protein	-
OW489_RS07880 (CHC155_15410)	-	1641777..1642565 (+)	789	WP_120856481.1	integrase	-
OW489_RS07885 (CHC155_15420)	-	1642669..1643148 (+)	480	WP_162966579.1	hypothetical protein	-
OW489_RS07890 (CHC155_15430)	comB2	1643145..1643429 (+)	285	WP_000736478.1	TrbC/VirB2 family protein	Machinery gene
OW489_RS07895 (CHC155_15440)	comB3	1643440..1643703 (+)	264	WP_001177712.1	hypothetical protein	Machinery gene
OW489_RS07900 (CHC155_15450)	-	1643714..1643950 (+)	237	WP_120824245.1	hypothetical protein	-
OW489_RS07905 (CHC155_15460)	comB4	1643950..1646532 (+)	2583	WP_120856479.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
OW489_RS07910	-	1646529..1646663 (+)	135	WP_120856477.1	type IV secretion system protein VirB7	-
OW489_RS07915 (CHC155_15470)	-	1646656..1647825 (+)	1170	WP_120856475.1	VirB8/TrbF family protein	-
OW489_RS07920 (CHC155_15480)	-	1647822..1649498 (+)	1677	WP_120856473.1	TrbG/VirB9 family P-type conjugative transfer protein	-
OW489_RS07925 (CHC155_15490)	comB10	1649495..1650697 (+)	1203	WP_120856471.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 860 a.a.
• Molecular weight: 99012.01 Da
• Isoelectric Point: 8.2869

>NTDB_id=80815 OW489_RS07905 WP_120856479.1 1643950..1646532(+) (comB4) [Helicobacter pylori strain CHC155]
MFENALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDIRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNETHSNTSSNKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGIYNEGENFHINPFSLEDSATNRAFLLHFYAQM
AKVDSYDDHKDKVEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALRINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLCPT

Nucleotide

• Length: 2583 bp

>NTDB_id=80815 OW489_RS07905 WP_120856479.1 1643950..1646532(+) (comB4) [Helicobacter pylori strain CHC155]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGTTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATATAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCCATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAGACCCATTCAAATACAAGCTCTAACAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGTGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTT
TCTTTTTTTCCTAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCAAATTCATGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGACAT
ACCATGATTATTGGCGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGTGCTTTAAAATACCCTAA
CATTGACATTCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATGAAGGCG
AAAACTTTCATATTAACCCTTTTTCATTAGAAGATAGCGCAACTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTGGATAGTTATGATGACCATAAGGATAAAGTAGAAGATAGAACAGCCCTTTTAAACGCTATTGATACGATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCACTCCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGACAGCATTTTACATAATGATGATGACGCTGG
GCTTTTAGCCTATTATGTCTTTCATAAGATGATTGATAGAGCCTTGAGAATCAATCGTGGGTTTTTGTGTTTTATTGATG
AGTTTAAATCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTGATTGTTTTAGCCTTACAAGACATTAACCAACTTAGTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCT
TATTAAACACTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTTGCCCAACATGA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-504)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.905	97.674	0.458