Detailed information NTG0080742

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: HXS58_RS01065
• Genome accession: NZ_AP023036
• Coordinates: 201263..203698 (-)
• Length: 811 a.a.
• NCBI ID: WP_034375719.1
• Uniprot ID: -
• Organism: Helicobacter suis strain NHP19-0020
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 196263..208698

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HXS58_RS01045 (NHP190020_02200)	comB10	197173..198432 (-)	1260	WP_176486095.1	DNA type IV secretion system protein ComB10	Machinery gene
HXS58_RS01050 (NHP190020_02210)	-	198422..199951 (-)	1530	WP_006564108.1	TrbG/VirB9 family P-type conjugative transfer protein	-
HXS58_RS01055 (NHP190020_02220)	-	199948..201039 (-)	1092	WP_176485135.1	type IV secretion system protein	-
HXS58_RS09660 (NHP190020_02230)	-	201049..201258 (-)	210	WP_141556969.1	hypothetical protein	-
HXS58_RS01065 (NHP190020_02240)	comB4	201263..203698 (-)	2436	WP_034375719.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
HXS58_RS01070 (NHP190020_02250)	-	203711..204031 (-)	321	WP_034375717.1	hypothetical protein	-
HXS58_RS01075 (NHP190020_02260)	comB3	204051..204314 (-)	264	WP_034375715.1	hypothetical protein	Machinery gene
HXS58_RS01080 (NHP190020_02270)	comB2	204325..204564 (-)	240	WP_050780158.1	TrbC/VirB2 family protein	Machinery gene
HXS58_RS01085 (NHP190020_02280)	-	204597..205367 (-)	771	WP_034375711.1	hypothetical protein	-
HXS58_RS01090 (NHP190020_02290)	-	205537..206403 (-)	867	WP_064430216.1	CfrBI family restriction endonuclease	-
HXS58_RS01095 (NHP190020_02300)	-	206390..207565 (-)	1176	WP_064430215.1	DNA-methyltransferase	-

Sequence

Protein

• Length: 811 a.a.
• Molecular weight: 93635.15 Da
• Isoelectric Point: 8.2514

>NTDB_id=80742 HXS58_RS01065 WP_034375719.1 201263..203698(-) (comB4) [Helicobacter suis strain NHP19-0020]
MLSDLFTFCKHKSIDYLAGLMPKTYSMVEENNILGIYDSQFLITKQENLVGLLELQGLSYLNLMQQDLEHYFNARQSALD
SIPLGVHLRIVAKRRKEQIKQNTQIDNPYARAIIAGFESKEIYDNRYYLVFESTTGTLKSFFEKKKLEMSTSIAESQDNQ
ERSKQKNITFINKHSMLKATMQRISHALKDFNPRELNSQEALRFYAEYINGFNIPLKPKMGILSDSYIASDVEFRKDYFL
INFKGKTTYQRFVGVKNYENQTITSVALSCLLHYACELDIIFSIEPLGIFESLHFLKVRKKFSFVNFVKEELDRYIDLVQ
ASRLSMQKIALNVLIRAESKESLDRHTEAVLNLLNNEGLVSKEETIGMIPSYFSFFPGRMDLNYRARYQTSSVMAALILF
EKNNRGFKANSWGDMPLSVFKNLDHSPYLFNFHNQEVQHKGVLAHNIARVNGHTMIIGATGAGKTTLMSYLMMSALKYPN
LDILALDRLNGLYSFTKYFGGVYNNDEEFYINPLTLEDSKENVEFLWSFYTYMLGIESTNKRDKELTEDQNAVRNAIGSM
YADHKKKSKQQEAYEPYTLEEFTNTFIKTQSEQIKGTLEPYLQNPIFNAREDCLEFKSRITTINMDSVINNQKDAGLLAY
YIFYKLIHRALHTNRGFFCFIDEFKSYAQNALMNDKINLIITQARKVNGVVALALQDIHQLDEVKNADSFIKNMGTLIFY
PQKNINTDKLKDQFGIKLSDLERHFLENTNVSSHQILIKNMNDSTSNVVDVSLAALGKYLPIFSSNASTMAHIKHLIKQY
PTSWREVFVHG

Nucleotide

• Length: 2436 bp

>NTDB_id=80742 HXS58_RS01065 WP_034375719.1 201263..203698(-) (comB4) [Helicobacter suis strain NHP19-0020]
ATGCTAAGTGATTTGTTTACATTTTGCAAACACAAGAGCATTGACTATCTAGCAGGCTTGATGCCTAAAACCTACTCTAT
GGTTGAGGAAAATAATATTCTAGGCATCTACGATTCCCAATTTTTAATCACCAAACAAGAGAATTTAGTAGGGTTGTTGG
AATTGCAGGGCTTGAGTTACTTGAATTTGATGCAACAGGATTTAGAACATTACTTTAATGCCCGCCAGAGTGCATTAGAT
AGTATCCCTCTAGGTGTGCATCTAAGAATTGTGGCTAAAAGAAGAAAAGAGCAAATCAAGCAGAATACACAGATAGATAA
TCCTTATGCTAGGGCTATCATTGCAGGATTTGAGAGCAAAGAGATTTATGATAACCGCTACTATCTTGTCTTTGAGAGCA
CAACAGGCACGCTTAAGAGCTTTTTTGAAAAGAAAAAGCTAGAGATGAGCACTTCTATAGCAGAGAGCCAAGATAATCAA
GAGCGCTCCAAGCAAAAAAACATCACCTTTATTAACAAGCACTCCATGCTCAAAGCAACCATGCAGAGAATAAGCCATGC
ACTCAAAGACTTCAACCCTAGAGAGCTTAACAGCCAAGAAGCCCTTAGATTTTATGCCGAATATATCAATGGCTTTAACA
TTCCTTTAAAACCTAAAATGGGCATTCTCAGCGATAGTTATATTGCTAGTGATGTAGAATTTAGAAAAGATTACTTCCTG
ATCAATTTTAAGGGCAAAACCACCTACCAACGCTTTGTAGGCGTGAAAAACTATGAAAACCAAACCATCACTTCTGTGGC
TCTCTCTTGCTTGTTACACTATGCATGTGAGCTAGACATTATCTTTTCTATAGAGCCTTTGGGCATTTTTGAGAGTTTGC
ATTTCTTAAAAGTACGCAAGAAATTTAGTTTTGTTAATTTTGTCAAAGAGGAGTTAGATAGATACATTGATCTGGTGCAA
GCTTCTAGACTCTCTATGCAAAAAATTGCCTTGAATGTGCTCATCAGAGCAGAAAGCAAAGAGAGTTTAGACAGACACAC
TGAGGCGGTTTTAAACTTGCTTAACAATGAAGGCTTGGTGAGCAAAGAGGAGACTATCGGGATGATACCCTCTTACTTTT
CTTTCTTTCCGGGTCGGATGGACTTAAACTATAGAGCTAGATACCAGACTTCTAGCGTGATGGCGGCCTTGATCTTGTTT
GAAAAGAATAACAGGGGCTTTAAAGCCAACTCTTGGGGGGATATGCCCTTGAGCGTGTTTAAAAACTTAGATCACTCCCC
TTATTTATTCAATTTCCACAACCAAGAAGTGCAACACAAGGGCGTGTTAGCCCACAATATTGCTAGAGTCAATGGACACA
CGATGATTATCGGAGCAACAGGAGCAGGCAAGACCACCTTGATGAGCTATTTGATGATGAGTGCTTTGAAATACCCAAAT
TTAGACATTTTAGCCCTAGATAGACTCAATGGCTTGTATTCCTTCACTAAATACTTTGGAGGGGTGTATAACAATGATGA
GGAGTTTTACATTAACCCTTTGACTTTAGAGGACTCTAAAGAAAATGTAGAGTTTTTGTGGAGCTTTTATACTTACATGC
TAGGCATTGAATCTACCAACAAAAGAGATAAAGAGCTCACAGAAGATCAAAATGCCGTGCGCAATGCTATTGGGAGTATG
TATGCAGACCACAAGAAAAAGAGCAAGCAGCAAGAAGCCTATGAGCCCTATACCTTAGAAGAGTTCACCAACACCTTTAT
TAAGACACAATCTGAACAAATCAAAGGCACTTTAGAGCCTTATTTGCAAAACCCCATTTTCAATGCCAGAGAGGATTGCC
TAGAGTTTAAAAGCCGCATCACCACCATTAATATGGATTCTGTGATCAACAACCAAAAAGACGCAGGGCTACTTGCTTAT
TACATTTTCTATAAGCTCATCCATAGAGCCTTGCACACCAATCGGGGCTTTTTTTGCTTCATTGATGAGTTTAAATCCTA
TGCGCAAAATGCGCTGATGAATGACAAGATTAATCTCATCATCACCCAAGCGCGCAAGGTCAATGGGGTGGTTGCTTTGG
CTTTGCAAGACATCCACCAGTTAGATGAAGTGAAAAATGCCGACAGCTTTATTAAAAATATGGGCACACTGATCTTCTAT
CCCCAAAAGAACATCAATACAGACAAGCTCAAAGACCAGTTTGGCATCAAACTTAGCGATTTAGAACGCCATTTCCTAGA
AAACACCAATGTTTCTAGCCACCAGATTTTAATTAAAAATATGAATGATAGCACTTCTAATGTGGTGGATGTGAGTTTGG
CTGCTCTAGGTAAGTATTTGCCTATCTTTAGTTCTAATGCCAGCACTATGGCACATATCAAGCATTTAATCAAACAATAC
CCAACTAGCTGGAGAGAAGTGTTTGTGCATGGGTAA

Domains

Predicted by InterproScan.

• Helicase HerA, central domain (DUF87) (450-629)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (187-385)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	51.673	99.507	0.514