Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   RL453_RS12685 Genome accession   NZ_CP134618
Coordinates   2588237..2589499 (+) Length   420 a.a.
NCBI ID   WP_000472302.1    Uniprot ID   P63789
Organism   Staphylococcus aureus strain IPLA15     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2583237..2594499
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RL453_RS12650 (RL453_12635) infC 2583765..2584292 (+) 528 WP_001791162.1 translation initiation factor IF-3 -
  RL453_RS12655 (RL453_12640) rpmI 2584321..2584521 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  RL453_RS12660 (RL453_12645) rplT 2584568..2584924 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  RL453_RS12665 (RL453_12650) - 2585066..2585674 (+) 609 WP_000032657.1 NUDIX domain-containing protein -
  RL453_RS12670 (RL453_12655) - 2585693..2586622 (+) 930 WP_001280022.1 hypothetical protein -
  RL453_RS12675 (RL453_12660) - 2586627..2586737 (+) 111 WP_001790560.1 hypothetical protein -
  RL453_RS12680 (RL453_12665) tig 2586785..2588086 (+) 1302 WP_000127573.1 trigger factor -
  RL453_RS12685 (RL453_12670) clpX 2588237..2589499 (+) 1263 WP_000472302.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  RL453_RS12690 (RL453_12675) yihA 2589653..2590243 (+) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  RL453_RS12695 (RL453_12680) hemA 2590460..2591806 (+) 1347 WP_000545466.1 glutamyl-tRNA reductase -
  RL453_RS12700 (RL453_12685) ccsA 2591828..2592643 (+) 816 WP_001157329.1 cytochrome c biogenesis protein -
  RL453_RS12705 (RL453_12690) hemC 2592685..2593611 (+) 927 WP_001230226.1 hydroxymethylbilane synthase -
  RL453_RS12710 (RL453_12695) - 2593633..2594301 (+) 669 WP_000805950.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46297.48 Da        Isoelectric Point: 4.2645

>NTDB_id=807079 RL453_RS12685 WP_000472302.1 2588237..2589499(+) (clpX) [Staphylococcus aureus strain IPLA15]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=807079 RL453_RS12685 WP_000472302.1 2588237..2589499(+) (clpX) [Staphylococcus aureus strain IPLA15]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATGACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63789

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531