Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RLT59_RS27455 Genome accession   NZ_CP134612
Coordinates   6020251..6020937 (-) Length   228 a.a.
NCBI ID   WP_311305857.1    Uniprot ID   -
Organism   Streptomyces sp. ITFR-6     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6015251..6025937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RLT59_RS27425 (RLT59_27425) - 6015434..6015907 (+) 474 WP_311305851.1 ATP-binding protein -
  RLT59_RS27430 (RLT59_27430) - 6015873..6016688 (-) 816 WP_311305852.1 serine hydrolase domain-containing protein -
  RLT59_RS27435 (RLT59_27435) - 6016775..6017242 (+) 468 WP_311305853.1 MerR family transcriptional regulator -
  RLT59_RS27440 (RLT59_27440) - 6017242..6018258 (+) 1017 WP_311305854.1 aldo/keto reductase -
  RLT59_RS27445 (RLT59_27445) - 6018302..6018859 (-) 558 WP_311305855.1 RDD family protein -
  RLT59_RS27450 (RLT59_27450) - 6018963..6020042 (-) 1080 WP_311305856.1 alpha/beta hydrolase -
  RLT59_RS27455 (RLT59_27455) vraR 6020251..6020937 (-) 687 WP_311305857.1 response regulator transcription factor Regulator
  RLT59_RS27460 (RLT59_27460) - 6020994..6022328 (-) 1335 WP_311305858.1 sensor histidine kinase -
  RLT59_RS27465 (RLT59_27465) - 6022449..6023411 (-) 963 WP_311305859.1 DUF4429 domain-containing protein -
  RLT59_RS27470 (RLT59_27470) - 6023496..6024707 (-) 1212 WP_311305860.1 alpha/beta hydrolase -
  RLT59_RS27475 (RLT59_27475) - 6024930..6025583 (-) 654 Protein_5435 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24053.80 Da        Isoelectric Point: 5.0761

>NTDB_id=806902 RLT59_RS27455 WP_311305857.1 6020251..6020937(-) (vraR) [Streptomyces sp. ITFR-6]
MTIRVIIVDDQAMVRAGFAALLAAQADIDVVGEAPDGRQGIDVSRRVHPDVVLMDVRMPEMDGLAAARELLNPPVGVAHV
PRVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLISAVRVVAAGDALLAPSVTRRLIADFARQRPSGAGSGGAALRLN
GLTPRETEVLGLIARGLSNQEIAGQLVLAEQTVKTHIGRILAKLDLRDRAQAVIFAYEAGVVVPGESP

Nucleotide


Download         Length: 687 bp        

>NTDB_id=806902 RLT59_RS27455 WP_311305857.1 6020251..6020937(-) (vraR) [Streptomyces sp. ITFR-6]
TTGACCATCCGTGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCGGGGTTCGCGGCGCTGCTCGCGGCGCAGGCCGA
TATCGATGTGGTCGGTGAGGCGCCGGACGGGCGCCAGGGCATCGACGTCAGCCGCCGGGTCCATCCGGACGTGGTGCTGA
TGGACGTCCGGATGCCCGAGATGGACGGACTGGCGGCGGCACGCGAGCTGCTGAACCCTCCGGTGGGCGTGGCGCATGTG
CCGAGGGTACTGATGCTGACCACGTTCGACGTGGACGACTACGTGTACGAGGCGCTGCGCGCCGGGGCGTCCGGTTTCCT
GCTGAAGGACGCGCCCCCGGCGGACCTGATCTCGGCGGTACGGGTGGTGGCGGCGGGTGACGCGCTGCTCGCCCCGTCGG
TGACCCGGCGCCTGATCGCGGACTTCGCCCGCCAACGGCCGTCCGGAGCGGGGAGCGGCGGGGCGGCGCTGCGGCTGAAC
GGGCTGACTCCGCGTGAGACGGAGGTGCTGGGGCTGATCGCCCGGGGGCTGTCGAACCAGGAGATCGCGGGGCAGCTGGT
ACTGGCGGAGCAGACGGTGAAGACGCACATCGGGCGGATACTCGCGAAGCTGGATCTGCGCGACCGGGCCCAGGCGGTGA
TCTTCGCGTACGAGGCGGGCGTGGTGGTACCGGGCGAGAGCCCCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(162-216)

Response regulator receiver domain (Response_reg)

(5-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.732

98.246

0.39
  degU Bacillus subtilis subsp. subtilis str. 168

37.555

100

0.377