Detailed information NTG0806586

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: P5661_RS13520
• Genome accession: NZ_CP120600
• Coordinates: 2553587..2555917 (-)
• Length: 776 a.a.
• NCBI ID: WP_249848131.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain PRO112
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2548587..2560917

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P5661_RS13485 (P5661_13485)	yqxA	2548925..2549263 (-)	339	WP_032726189.1	YqxA family protein	-
P5661_RS13490 (P5661_13490)	spoIIP	2549280..2550485 (-)	1206	WP_014477383.1	spore autolysin SpoIIP	-
P5661_RS13495 (P5661_13495)	gpr	2550548..2551654 (-)	1107	WP_014480309.1	GPR endopeptidase	-
P5661_RS13500 (P5661_13500)	rpsT	2551858..2552124 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
P5661_RS13505 (P5661_13505)	holA	2552139..2553182 (-)	1044	WP_029317888.1	DNA polymerase III subunit delta	-
P5661_RS13510 (P5661_13510)	-	2553222..2553335 (-)	114	WP_122060479.1	hypothetical protein	-
P5661_RS13515 (P5661_13515)	yqzM	2553412..2553546 (+)	135	WP_003229983.1	YqzM family protein	-
P5661_RS13520 (P5661_13520)	comEC	2553587..2555917 (-)	2331	WP_249848131.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
P5661_RS13525 (P5661_13525)	comEB	2555921..2556490 (-)	570	WP_072174291.1	ComE operon protein 2	-
P5661_RS13530 (P5661_13530)	comEA	2556557..2557174 (-)	618	WP_277708803.1	competence protein ComEA	Machinery gene
P5661_RS13535 (P5661_13535)	comER	2557258..2558079 (+)	822	WP_021480064.1	late competence protein ComER	-
P5661_RS13540 (P5661_13540)	yqeM	2558145..2558888 (-)	744	WP_070547553.1	class I SAM-dependent methyltransferase	-
P5661_RS13545 (P5661_13545)	rsfS	2558885..2559241 (-)	357	WP_014480315.1	ribosome silencing factor	-
P5661_RS13550 (P5661_13550)	yqeK	2559259..2559819 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
P5661_RS13555 (P5661_13555)	nadD	2559809..2560378 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
P5661_RS13560 (P5661_13560)	yhbY	2560390..2560680 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86643.24 Da
• Isoelectric Point: 7.1784

>NTDB_id=806586 P5661_RS13520 WP_249848131.1 2553587..2555917(-) (comEC) [Bacillus subtilis strain PRO112]
MRNSRLLLPMAAASATVGITAAAYFPAIFLFILFLLIMLIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVKTPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIIIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFHQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVEVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGG
ICCTVMFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAEILLKHHKVKRLVIPKGFVSEPKDEKVLQAAREEGVAIEEVKRGDVLQIKDLQFHVLSPE
APDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMNVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGIN
NRYHHPHHEVLQLLQRHSIRVLRTDQNGTIQYRYKNRGGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=806586 P5661_RS13520 WP_249848131.1 2553587..2555917(-) (comEC) [Bacillus subtilis strain PRO112]
ATGCGTAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGTTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATGTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTAAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATCCAAAACTGCAGCGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTCTGCCTCCTGATTCGGCAGGAATTGTACAGGCACTTACAGTCGGTGACAGAT
TTTATGTGGAGGACGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCGATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATAATCCGTCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGTCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCATCA
GGTTAAAACCTCCTTGGGGCAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTCCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCAGATGTTGAAGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACCGGAGGC
ATTTGCTGCACGGTGATGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAGCAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGATTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGGCAGCCAGGGAAG
AGGGAGTGGCAATTGAAGAGGTGAAGCGAGGCGATGTGTTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCGGAA
GCACCTGATCCGGCAAGCAAAAATAATTCATCTCTCGTTCTTTGGATGGAGACGGGCGGTATGAGCTGGATCTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAAGAGGTGATGAACGTGTTTCCGAATATAAAAGCAGATGTGTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGATAAAC
AATCGGTACCACCATCCTCATCATGAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGACCAAAA
CGGAACGATCCAATATAGATATAAAAACAGAGGTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	98.325	100	0.983