Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   P3R60_RS08840 Genome accession   NZ_CP120510
Coordinates   1707096..1709354 (-) Length   752 a.a.
NCBI ID   WP_218654431.1    Uniprot ID   -
Organism   Streptococcus pluranimalium strain SP21-2     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1705676..1707021 1707096..1709354 flank 75


Gene organization within MGE regions


Location: 1705676..1709354
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3R60_RS08840 clpE 1707096..1709354 (-) 2259 WP_218654431.1 ATP-dependent Clp protease ATP-binding subunit Regulator

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83601.66 Da        Isoelectric Point: 4.8030

>NTDB_id=805874 P3R60_RS08840 WP_218654431.1 1707096..1709354(-) (clpE) [Streptococcus pluranimalium strain SP21-2]
MLCQNCQLNESTIHLYTNVNGKQKQVDLCQNCYQIMKTDPKNNLLSNLGRENASSSMNPFFDDFFGDLNNFRAFSGDLPN
SPKTQSGGQGGNNGIGNRHPNAPLGGAQQKPQGLLEEFGINITDIARQGDIDPVIGRDEEILRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDADVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRQDVILFIDEIHEIVGAG
NAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSA
DAIEAAAILSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPQEIDQRLVEAENLKAQATRDEDYERAAYFRDQIAKYK
EMQAQKIDDHDTPVITEQNIEAIIEQKTNIPVGDLKEKEQSQLIHLADDLKSHVIGQDDAVDKIAKAIRRNRVGLGSPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILL
DEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAREGRTNSVLNQLGDFFSPEFMN
RFDGIIEFKALEKENLLTIVDLMLKDVNDRLATNGLHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLE
NPSEKNLRAIMTSNGNIIIKSNTKAEAVVEEN

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=805874 P3R60_RS08840 WP_218654431.1 1707096..1709354(-) (clpE) [Streptococcus pluranimalium strain SP21-2]
ATGCTTTGTCAAAATTGTCAATTAAACGAATCAACTATCCATTTATATACTAATGTTAATGGCAAACAAAAACAAGTCGA
TCTTTGCCAAAACTGTTATCAAATCATGAAAACAGATCCCAAAAACAACCTTTTATCTAATCTGGGTCGAGAAAACGCAT
CATCTTCTATGAATCCATTTTTTGATGATTTCTTCGGTGACTTAAATAACTTCCGTGCCTTCAGCGGTGACCTTCCAAAC
AGTCCTAAAACACAATCTGGTGGTCAGGGAGGAAACAATGGAATTGGAAATCGTCATCCAAATGCTCCTCTAGGCGGTGC
TCAACAAAAGCCTCAAGGACTCTTAGAAGAGTTCGGTATTAATATCACTGATATTGCACGCCAAGGCGATATTGATCCCG
TTATTGGTCGCGATGAAGAAATCCTTCGTGTTATCGAAATTCTAAACCGTCGTACCAAAAATAATCCTGTCCTCATTGGT
GAGCCAGGTGTTGGTAAAACTGCTGTCGTTGAAGGACTGGCTCAAAAGATTGTTGATGCTGATGTTCCTCAAAAACTCCA
AGGAAAGCAAGTCATCCGTTTGGATGTTGTCAGCCTTGTTCAGGGGACAGGCATCCGTGGACAATTTGAAGAACGTATGC
AAAAACTCATGGAAGAAATCCGTAATCGTCAAGATGTGATTCTCTTCATTGATGAGATTCATGAGATTGTTGGTGCAGGT
AATGCTGGTGATGGAAACATGGACGCCGGCAATATCCTAAAACCTGCTCTAGCTCGTGGTGAGCTACAACTAGTCGGTGC
TACTACTCTCAATGAATATCGTATCATTGAAAAAGATGCTGCTCTGGAACGTCGTATGCAGCCCGTCAAAGTTGATGAGC
CAAGTGTTGAGGAAACTATCACCATCTTAAAAGGTATTCAACCCAAATACGAAGACTATCACCATGTCAAATACAGTGCT
GATGCTATTGAAGCGGCAGCTATCCTTTCAAATCGTTACATTCAAGACCGCTTCCTTCCAGATAAGGCTATCGACCTACT
TGATGAAGCTGGATCAAAAATGAATTTAACCTTAAATTTTGTTGATCCGCAAGAAATCGATCAACGCCTGGTGGAAGCCG
AAAACCTCAAAGCTCAAGCAACTCGAGATGAAGATTATGAACGCGCAGCTTATTTCCGTGACCAAATTGCTAAATACAAA
GAAATGCAAGCGCAAAAAATCGATGACCACGATACTCCAGTCATCACTGAACAAAATATCGAAGCCATCATTGAACAAAA
AACTAATATTCCAGTCGGCGATCTCAAAGAAAAAGAACAAAGTCAATTAATTCATTTGGCTGACGACCTTAAATCACACG
TTATTGGACAAGACGATGCTGTTGATAAAATCGCAAAAGCCATTCGTCGTAACCGTGTCGGACTTGGTTCGCCAAATCGC
CCAATCGGTTCCTTCCTCTTTGTTGGTCCAACTGGTGTCGGTAAAACTGAACTCTCAAAACAACTAGCAATCGAGCTCTT
TGGTTCAGCAGACAGCATGATTCGCTTTGATATGTCCGAGTACATGGAAAAACATGCCGTCGCCAAACTTGTCGGAGCTC
CTCCAGGTTATGTTGGTTATGAAGAAGCTGGTCAATTGACAGAAAAAGTTCGTCGCAATCCATACTCACTCATTCTCTTG
GATGAAGTTGAGAAAGCTCACCCAGATGTTATGCATATGTTCTTACAAGTTCTTGACGATGGTCGTTTGACTGATGGTCA
AGGTCGTACCGTTAGCTTCAAAGATACCATTATCATCATGACCTCGAATGCTGGAACAGGCAAGGTTGAAGCTTCTGTTG
GTTTTGGAGCAGCTCGTGAAGGTCGTACCAACTCCGTTCTTAACCAACTTGGAGACTTCTTTAGCCCAGAATTCATGAAC
CGCTTTGATGGTATTATCGAATTCAAAGCTCTTGAAAAAGAAAATCTCCTTACTATTGTTGATCTCATGCTCAAAGATGT
CAATGATAGACTTGCTACCAACGGTCTTCACCTTGATGTCACCGAGAAAGTTAAGGAAAAATTGGTTGATCTTGGCTATG
ATCCAAAAATGGGAGCTCGTCCACTTCGCAGAACAATTCAAGACCATATCGAAGATGCTATCACAGATTTCTATCTTGAA
AATCCTTCAGAGAAAAATCTCCGTGCCATCATGACTTCTAATGGAAACATCATTATCAAATCAAATACGAAAGCTGAAGC
TGTCGTAGAAGAAAACTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(651-726)

AAA domain (Cdc48 subfamily) (AAA_2)

(480-643)

AAA lid domain (AAA_lid_9)

(295-392)

ATPase family associated with various cellular activities (AAA) (AAA)

(157-276)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

86.418

99.867

0.863
  clpE Streptococcus pneumoniae Rx1

82.649

100

0.83
  clpE Streptococcus pneumoniae D39

82.649

100

0.83
  clpE Streptococcus pneumoniae R6

82.649

100

0.83
  clpE Streptococcus pneumoniae TIGR4

82.649

100

0.83
  clpC Lactococcus lactis subsp. cremoris KW2

75.6

99.734

0.754
  clpC Bacillus subtilis subsp. subtilis str. 168

49.354

92.686

0.457
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.625

84.707

0.395
  clpC Streptococcus pneumoniae Rx1

47.368

83.378

0.395
  clpC Streptococcus pneumoniae D39

47.368

83.378

0.395
  clpC Streptococcus pneumoniae TIGR4

47.209

83.378

0.394
  clpC Streptococcus mutans UA159

47.182

82.58

0.39
  clpC Streptococcus thermophilus LMD-9

46.057

84.309

0.388
  clpC Streptococcus thermophilus LMG 18311

45.728

84.043

0.384