Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   P3R60_RS08475 Genome accession   NZ_CP120510
Coordinates   1643142..1644443 (+) Length   433 a.a.
NCBI ID   WP_218653583.1    Uniprot ID   -
Organism   Streptococcus pluranimalium strain SP21-2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1638142..1649443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3R60_RS08445 - 1638543..1639181 (+) 639 WP_316606211.1 response regulator transcription factor -
  P3R60_RS08450 - 1639229..1640629 (+) 1401 WP_316606212.1 Cof-type HAD-IIB family hydrolase -
  P3R60_RS08455 - 1640629..1640988 (+) 360 WP_316606213.1 S1 RNA-binding domain-containing protein -
  P3R60_RS08460 - 1641064..1641287 (+) 224 Protein_1620 hypothetical protein -
  P3R60_RS08465 cysK 1641439..1642368 (-) 930 WP_316606214.1 cysteine synthase A -
  P3R60_RS08470 - 1642466..1643095 (-) 630 WP_115130708.1 YigZ family protein -
  P3R60_RS08475 comFA/cflA 1643142..1644443 (+) 1302 WP_218653583.1 DEAD/DEAH box helicase Machinery gene
  P3R60_RS08480 - 1644440..1645102 (+) 663 WP_115130706.1 ComF family protein -
  P3R60_RS08485 hpf 1645183..1645731 (+) 549 WP_115130705.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49273.08 Da        Isoelectric Point: 9.4254

>NTDB_id=805873 P3R60_RS08475 WP_218653583.1 1643142..1644443(+) (comFA/cflA) [Streptococcus pluranimalium strain SP21-2]
MKTLKEKSGCWFAGSSITAEEREEAIKIPAFTQENGNLTCNRCSEKITTDWQLPDGTRYCRSCILLGRLTEDDHLYYFPP
KTFPKRNALQWKGKLTSYQKEISGSLVQSLEDRKDSLVHAVTGAGKTEMIYEVVARVIDEGGQVCLASPRIDVCIELYKR
LSKDFSCDIDLLHGDSEPYSCSPLIIATTHQLLKFYHSFDLILVDEVDAFPYVDNKILYHAVRTAKKADGLTIYMTATST
EELDKQVKKGILKKRTLSRRFHGNPLIEPRNIWLTGLEKKVDSGKIPLKLKRYLDRQFQTGYPLLIFVPDIAFGKKIKKV
LCQQYPKVSIGFVSSNSPDRLEEVEMFRHGDLRVLISTTILERGVTFPKVDVFVLLAHHKLFTSSSLIQIGGRVGRSLER
PTGDLFFFHEGVTRAIKKTKKEIRQMNHLGGFK

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=805873 P3R60_RS08475 WP_218653583.1 1643142..1644443(+) (comFA/cflA) [Streptococcus pluranimalium strain SP21-2]
ATGAAAACGCTAAAAGAAAAAAGTGGTTGCTGGTTTGCAGGTTCTAGTATCACGGCAGAGGAAAGAGAAGAAGCCATAAA
GATACCTGCTTTCACTCAAGAAAATGGGAATCTTACTTGTAATAGATGTTCAGAAAAGATTACAACTGACTGGCAGTTGC
CGGATGGGACACGTTATTGTCGCTCCTGTATTTTATTAGGTAGATTGACGGAAGATGACCATCTCTATTATTTTCCACCG
AAAACTTTCCCAAAAAGAAATGCTTTACAATGGAAAGGCAAATTAACTAGTTATCAAAAAGAAATTTCAGGTAGTCTCGT
GCAATCACTTGAGGATAGAAAGGATAGTTTGGTACATGCCGTAACAGGAGCTGGAAAAACGGAAATGATCTATGAAGTAG
TCGCTCGAGTGATTGATGAAGGTGGACAAGTTTGTTTGGCCAGTCCTCGTATAGATGTTTGTATTGAATTATACAAGCGA
CTCAGCAAGGATTTTTCTTGTGATATTGATTTGTTACATGGTGATTCTGAACCATATAGTTGCTCCCCTTTGATTATTGC
AACTACCCATCAGCTGTTAAAGTTTTATCACTCTTTTGATCTTATATTAGTTGATGAAGTAGATGCCTTTCCCTACGTCG
ATAATAAAATACTTTATCATGCTGTTAGAACAGCGAAAAAAGCAGATGGTCTAACCATCTATATGACAGCAACTTCGACA
GAAGAATTAGATAAACAAGTCAAAAAAGGAATCTTAAAAAAACGAACTTTATCGCGAAGATTTCATGGGAATCCCTTAAT
AGAACCACGGAATATTTGGCTAACTGGACTAGAGAAAAAGGTTGACTCTGGTAAGATACCATTGAAACTAAAACGATATC
TAGATAGGCAATTTCAAACAGGCTACCCGCTTTTAATTTTTGTACCAGATATTGCTTTTGGAAAGAAAATAAAGAAAGTT
CTTTGTCAACAATATCCCAAAGTTTCTATAGGTTTTGTCTCTAGTAATAGTCCAGATAGATTAGAAGAAGTAGAAATGTT
CAGACATGGTGATTTAAGAGTTCTCATATCAACGACAATTTTAGAAAGGGGAGTGACATTTCCTAAAGTGGATGTCTTTG
TTTTACTAGCTCATCATAAATTATTTACTAGCTCTAGTCTTATTCAGATAGGTGGTCGAGTAGGACGGTCATTAGAGAGA
CCGACAGGAGATCTATTCTTCTTTCATGAAGGGGTTACAAGGGCTATCAAAAAGACTAAAAAAGAAATTCGACAGATGAA
CCATTTGGGAGGCTTCAAGTGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(297-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

58.333

99.769

0.582
  comFA/cflA Streptococcus pneumoniae D39

58.333

99.769

0.582
  comFA/cflA Streptococcus pneumoniae R6

58.333

99.769

0.582
  comFA/cflA Streptococcus pneumoniae TIGR4

58.333

99.769

0.582
  comFA/cflA Streptococcus mitis NCTC 12261

57.87

99.769

0.577
  comFA/cflA Streptococcus mitis SK321

56.944

99.769

0.568
  comFA Lactococcus lactis subsp. cremoris KW2

46.853

99.076

0.464
  comFA Bacillus subtilis subsp. subtilis str. 168

36.977

99.307

0.367
  comFA Latilactobacillus sakei subsp. sakei 23K

38.916

93.764

0.365