Detailed information
Bioinformatically predicted
Overview
| Name | comK/comK1 | Type | Regulator |
| Locus tag | P5W77_RS09200 | Genome accession | NZ_CP120424 |
| Coordinates | 1962257..1962832 (-) | Length | 191 a.a. |
| NCBI ID | WP_001829272.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain 32FSE06 | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1925963..1961720 | 1962257..1962832 | flank | 537 |
Gene organization within MGE regions
Location: 1925963..1962832
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P5W77_RS08975 | - | 1925963..1926883 (-) | 921 | WP_002501737.1 | peptidoglycan recognition family protein | - |
| P5W77_RS08980 | - | 1926936..1927322 (-) | 387 | WP_002446772.1 | phage holin family protein | - |
| P5W77_RS08985 | - | 1927324..1927605 (-) | 282 | WP_002501736.1 | hypothetical protein | - |
| P5W77_RS08990 | - | 1927642..1928052 (-) | 411 | WP_002501735.1 | hypothetical protein | - |
| P5W77_RS08995 | - | 1928073..1931528 (-) | 3456 | WP_002501734.1 | phage tail spike protein | - |
| P5W77_RS09000 | - | 1931525..1932295 (-) | 771 | WP_049392193.1 | tail protein | - |
| P5W77_RS09005 | - | 1932298..1936479 (-) | 4182 | WP_002501731.1 | phage tail tape measure protein | - |
| P5W77_RS09010 | - | 1936543..1936755 (-) | 213 | WP_032606956.1 | hypothetical protein | - |
| P5W77_RS09015 | - | 1936809..1937153 (-) | 345 | WP_002501729.1 | hypothetical protein | - |
| P5W77_RS09020 | - | 1937177..1937881 (-) | 705 | WP_002484613.1 | hypothetical protein | - |
| P5W77_RS09025 | - | 1937887..1938324 (-) | 438 | WP_002501727.1 | hypothetical protein | - |
| P5W77_RS09030 | - | 1938324..1938662 (-) | 339 | WP_002501726.1 | hypothetical protein | - |
| P5W77_RS09035 | - | 1938662..1938991 (-) | 330 | WP_002501725.1 | phage head closure protein | - |
| P5W77_RS09040 | - | 1938963..1939271 (-) | 309 | WP_002484579.1 | phage head-tail connector protein | - |
| P5W77_RS09045 | - | 1939298..1940455 (-) | 1158 | WP_002501724.1 | phage major capsid protein | - |
| P5W77_RS09050 | - | 1940480..1941226 (-) | 747 | WP_002501723.1 | head maturation protease, ClpP-related | - |
| P5W77_RS09055 | - | 1941226..1942362 (-) | 1137 | WP_002501722.1 | phage portal protein | - |
| P5W77_RS09060 | - | 1942378..1944012 (-) | 1635 | WP_002501721.1 | terminase TerL endonuclease subunit | - |
| P5W77_RS09065 | - | 1943996..1944334 (-) | 339 | WP_002501720.1 | hypothetical protein | - |
| P5W77_RS09070 | - | 1944653..1944943 (-) | 291 | WP_002501719.1 | HNH endonuclease | - |
| P5W77_RS09075 | - | 1945226..1945837 (-) | 612 | WP_002501718.1 | hypothetical protein | - |
| P5W77_RS09080 | - | 1946041..1946532 (-) | 492 | WP_002501717.1 | sigma factor-like helix-turn-helix DNA-binding protein | - |
| P5W77_RS09085 | - | 1946856..1948730 (-) | 1875 | WP_002501716.1 | DNA primase family protein | - |
| P5W77_RS09090 | - | 1948760..1948954 (-) | 195 | WP_002501715.1 | hypothetical protein | - |
| P5W77_RS09095 | - | 1949033..1949278 (-) | 246 | WP_002501714.1 | hypothetical protein | - |
| P5W77_RS09100 | - | 1949350..1949565 (+) | 216 | WP_002491630.1 | hypothetical protein | - |
| P5W77_RS09105 | - | 1949583..1949885 (-) | 303 | WP_002501713.1 | MazG-like family protein | - |
| P5W77_RS09110 | - | 1949951..1950490 (+) | 540 | WP_277375010.1 | hypothetical protein | - |
| P5W77_RS09115 | - | 1950653..1951042 (-) | 390 | WP_002501711.1 | hypothetical protein | - |
| P5W77_RS09120 | - | 1951298..1953016 (-) | 1719 | WP_002501710.1 | hypothetical protein | - |
| P5W77_RS09125 | - | 1953066..1953548 (-) | 483 | WP_002501709.1 | DUF669 domain-containing protein | - |
| P5W77_RS09130 | - | 1953600..1953806 (-) | 207 | WP_002501708.1 | hypothetical protein | - |
| P5W77_RS09135 | - | 1953825..1955636 (-) | 1812 | WP_002501707.1 | AAA family ATPase | - |
| P5W77_RS09140 | - | 1955636..1955932 (-) | 297 | WP_002484599.1 | hypothetical protein | - |
| P5W77_RS09145 | - | 1955925..1956242 (-) | 318 | WP_002501706.1 | hypothetical protein | - |
| P5W77_RS09150 | - | 1956245..1957486 (-) | 1242 | WP_002501705.1 | SNF2-related protein | - |
| P5W77_RS09155 | - | 1957634..1957828 (-) | 195 | WP_002491611.1 | DUF1270 family protein | - |
| P5W77_RS09160 | - | 1958313..1958621 (-) | 309 | WP_002501703.1 | DUF771 domain-containing protein | - |
| P5W77_RS09165 | - | 1958675..1958866 (-) | 192 | WP_002501702.1 | helix-turn-helix transcriptional regulator | - |
| P5W77_RS09170 | - | 1959027..1959362 (+) | 336 | WP_002446811.1 | helix-turn-helix transcriptional regulator | - |
| P5W77_RS09175 | - | 1959518..1959892 (+) | 375 | WP_002501701.1 | hypothetical protein | - |
| P5W77_RS09180 | - | 1959905..1960579 (+) | 675 | WP_049392317.1 | Ltp family lipoprotein | - |
| P5W77_RS09185 | - | 1960656..1961720 (+) | 1065 | WP_002491600.1 | site-specific integrase | - |
| P5W77_RS09200 | comK/comK1 | 1962257..1962832 (-) | 576 | WP_001829272.1 | competence protein ComK | Regulator |
Sequence
Protein
Download Length: 191 a.a. Molecular weight: 22782.87 Da Isoelectric Point: 9.2887
>NTDB_id=805649 P5W77_RS09200 WP_001829272.1 1962257..1962832(-) (comK/comK1) [Staphylococcus epidermidis strain 32FSE06]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN
Nucleotide
Download Length: 576 bp
>NTDB_id=805649 P5W77_RS09200 WP_001829272.1 1962257..1962832(-) (comK/comK1) [Staphylococcus epidermidis strain 32FSE06]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comK/comK1 | Staphylococcus aureus MW2 |
76.757 |
96.859 |
0.743 |
| comK/comK1 | Staphylococcus aureus N315 |
76.757 |
96.859 |
0.743 |