Detailed information NTG0804374

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3U53_RS04180
• Genome accession: NZ_CP120189
• Coordinates: 928358..929401 (+)
• Length: 347 a.a.
• NCBI ID: WP_014613481.1
• Uniprot ID: -
• Organism: Staphylococcus pseudintermedius strain Dog012
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 923358..934401

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3U53_RS04155 (P3U53_04155)	-	923614..924336 (+)	723	WP_014613476.1	type 1 glutamine amidotransferase	-
P3U53_RS04160 (P3U53_04160)	-	925304..926302 (-)	999	WP_014613477.1	FUSC family protein	-
P3U53_RS04165 (P3U53_04165)	map	926399..927160 (+)	762	WP_323693631.1	type I methionyl aminopeptidase	-
P3U53_RS04170 (P3U53_04170)	-	927258..927647 (+)	390	WP_014613479.1	hypothetical protein	-
P3U53_RS04175 (P3U53_04175)	liaF	927660..928361 (+)	702	WP_014613480.1	cell wall-active antibiotics response protein LiaF	-
P3U53_RS04180 (P3U53_04180)	vraS	928358..929401 (+)	1044	WP_014613481.1	sensor histidine kinase	Regulator
P3U53_RS04185 (P3U53_04185)	vraR	929391..930020 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
P3U53_RS04190 (P3U53_04190)	-	930587..931168 (-)	582	WP_063278570.1	beta-class carbonic anhydrase	-
P3U53_RS04195 (P3U53_04195)	-	931201..932538 (-)	1338	WP_015729387.1	YihY/virulence factor BrkB family protein	-
P3U53_RS04200 (P3U53_04200)	-	932754..933041 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
P3U53_RS04205 (P3U53_04205)	-	933049..933507 (-)	459	WP_014613486.1	low molecular weight protein-tyrosine-phosphatase	-
P3U53_RS04210 (P3U53_04210)	-	933641..933844 (+)	204	WP_014613487.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39939.24 Da
• Isoelectric Point: 5.0435

>NTDB_id=804374 P3U53_RS04180 WP_014613481.1 928358..929401(+) (vraS) [Staphylococcus pseudintermedius strain Dog012]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWLKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDEKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=804374 P3U53_RS04180 WP_014613481.1 928358..929401(+) (vraS) [Staphylococcus pseudintermedius strain Dog012]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATTGACAA
AGTGTTCACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGTATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATTGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGCTCAAGCAA
CAAATCGTTCGTGCCTTTGAAGGTGAAACAGTGGGCATCAATGATCAACAACTCGAGCTGTATAATGAAACGATTGAATT
ATATCAAGCACTCGTCCCATTAAATCAAGAATTGCATAAAATGCGAATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGACAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAAGAAACAGATTTAGCACCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGCGCTCTGTTACTTCACTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGAATTAAATCGCTTGTGACGGATCTACAACGTAAAGTACCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTACCTAAAGGCATTGAGGATCACCTTTTTAGAATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGGACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGAAAAGTTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACA
TTTCATATCGTCTCATTACCTGATGCGGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.862	100	0.839