Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   L6480_RS06210 Genome accession   NZ_AP022981
Coordinates   1205448..1208048 (+) Length   866 a.a.
NCBI ID   WP_000365403.1    Uniprot ID   A0A9W4AF42
Organism   Bacillus cereus strain 30048     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 1200448..1213048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6480_RS06170 (BC30048_1134) - 1200451..1200984 (+) 534 WP_002197523.1 hypothetical protein -
  L6480_RS06175 (BC30048_1135) prsA 1201213..1202070 (-) 858 WP_142408726.1 peptidylprolyl isomerase PrsA -
  L6480_RS06180 (BC30048_1136) - 1202199..1202330 (-) 132 WP_001120851.1 DUF3941 domain-containing protein -
  L6480_RS06185 (BC30048_1137) - 1202431..1203288 (+) 858 WP_000364431.1 YitT family protein -
  L6480_RS06190 (BC30048_1138) - 1203314..1203511 (-) 198 WP_000527407.1 DUF3813 domain-containing protein -
  L6480_RS06195 (BC30048_1139) - 1203512..1203652 (-) 141 WP_000516816.1 hypothetical protein -
  L6480_RS06200 (BC30048_1140) - 1203758..1204567 (-) 810 WP_001041232.1 Cof-type HAD-IIB family hydrolase -
  L6480_RS06205 (BC30048_1141) - 1205059..1205238 (+) 180 WP_000531421.1 YjzC family protein -
  L6480_RS06210 (BC30048_1142) clpC 1205448..1208048 (+) 2601 WP_000365403.1 ATP-dependent chaperone ClpB Regulator
  L6480_RS06215 (BC30048_1143) - 1208087..1208269 (-) 183 WP_001211116.1 YjzD family protein -
  L6480_RS06220 (BC30048_1144) - 1208426..1209160 (+) 735 WP_000028712.1 hydrolase -
  L6480_RS06225 (BC30048_1145) - 1209190..1210062 (+) 873 WP_002164601.1 NAD(P)-dependent oxidoreductase -
  L6480_RS06230 (BC30048_1146) comZ 1210117..1210293 (+) 177 WP_001986215.1 ComZ family protein Regulator
  L6480_RS06235 (BC30048_1147) fabH 1210683..1211615 (+) 933 WP_001100547.1 beta-ketoacyl-ACP synthase III -
  L6480_RS06240 (BC30048_1148) fabF 1211647..1212885 (+) 1239 WP_000412656.1 beta-ketoacyl-ACP synthase II -

Sequence

Protein


Download         Length: 866 a.a.        Molecular weight: 97369.35 Da        Isoelectric Point: 5.1561

>NTDB_id=80437 L6480_RS06210 WP_000365403.1 1205448..1208048(+) (clpC) [Bacillus cereus strain 30048]
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLEEQDGLAVRIFQKMNVDIEALKQGAESLIKKKPSVTGSGAE
VGKLYVTSALQQLLVRAGKEAEKLQDDYISVEHVLLAFSEEKGDINQLFTRLHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKETDRGSQERLKTLQRELSDLKEVASGMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNKAAELRHGKIPAIEKELKEAEEMGAHNKQETRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVVLLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEEDGSIKEESRDLVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

Nucleotide


Download         Length: 2601 bp        

>NTDB_id=80437 L6480_RS06210 WP_000365403.1 1205448..1208048(+) (clpC) [Bacillus cereus strain 30048]
ATGGACTTAAATCAAATGACAACAAAAACACAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCATCACCA
AGAGGTGGATACTGTTCATCTATTACTTGCATTATTAGAAGAGCAAGATGGATTAGCAGTACGTATATTTCAAAAAATGA
ATGTTGATATAGAAGCATTAAAGCAAGGTGCTGAAAGTTTAATTAAAAAGAAACCTTCTGTAACGGGGAGCGGTGCAGAA
GTTGGAAAATTGTATGTAACGAGCGCTCTGCAACAACTTCTTGTAAGAGCAGGAAAAGAAGCAGAAAAACTGCAGGATGA
TTACATTTCAGTAGAACATGTATTGCTTGCTTTTTCTGAAGAAAAAGGCGATATAAATCAATTATTTACAAGATTGCATA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACGAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGCCGTGATTTAGTGGCGGAAGTGAGAGCAGGGAAAATCGATCCTGTAATCGGCCGTGA
TAGTGAAATACGACGTGTGATTCGTATTCTTTCACGTAAAACGAAAAACAATCCTGTTTTAATTGGGGAGCCAGGTGTTG
GTAAAACAGCAATCGTTGAAGGGCTAGCACAGCGTATCGTGAAAAAGGATGTACCTGAAGGATTGAAAGATAGAACGATT
TTTGCGTTAGATATGAGTGCGCTCGTAGCAGGTGCGAAATTCCGTGGTGAGTTCGAAGAGCGTCTGCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGACGCATTTTATTATTCATTGATGAACTTCATACAATAGTTGGAGCGGGTAAAACAGAGG
GAGCCATGGATGCAGGAAATATGTTAAAACCGATGCTTGCGCGCGGTGAACTGCATTGTATCGGGGCGACGACGCTCGAT
GAATATCGCAAATATATTGAGAAAGATCCAGCGCTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAACCAACTGTTGA
AGATACAATTTCCATTTTACGTGGATTAAAAGAACGCTTTGAAATTTATCACGGTGTAAATATTCATGACCGTGCGATTG
TAGCAGCGTCAGTTTTATCAGATCGATATATTTCAGATCGCTTCTTACCCGATAAAGCAATTGACCTTGTTGATGAAGCG
TGTGCAACAATTCGTACAGAAATTGATTCTATGCCAACAGAATTAGATGAAGTAACGCGCCGCATTATGCAGCTGGAAAT
TGAAGAAGCGGCTCTTGGGAAAGAAACGGATCGTGGTAGCCAAGAGCGTCTAAAAACATTGCAACGTGAATTATCGGATT
TAAAAGAAGTTGCAAGTGGCATGAGAGCGAAATGGGAGAAAGAAAAAGAAGACATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAACGTTTGCGTCGTGAATTAGAAGAAGCAGAAGGCAATTACGATTTAAATAAAGCAGCCGAACTTCGTCACGG
GAAAATTCCCGCAATTGAAAAAGAGTTAAAAGAAGCGGAAGAAATGGGCGCGCATAATAAACAAGAAACTCGTTTATTAC
GTGAGGAAGTAAGTGAAGAAGAAATTGCAGATATTGTTTCACGCTGGACTGGTATTCCTGTTGCGAAACTCGTGGAAGGT
GAACGCGAGAAATTATTACGCTTAGAGCAAATCTTATCAGAGCGTGTCATCGGACAAGAGGAAGCAGTAAGCTTAGTGTC
AGACGCAGTTCTTCGTGCTCGCGCTGGTATTAAAGATCCGAACCGCCCGATTGGTTCTTTCATCTTCTTAGGACCAACAG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCCCAGTCTTTATTCGATAGTGAAGAGCAAATGATTCGCATTGACATG
TCTGAGTATATGGAAAAACACGCCGTGTCTCGCTTAATTGGTGCACCTCCTGGATATGTAGGATATGAAGAAGGCGGTCA
ATTAACAGAAGCGGTAAGACGTAAACCATATTCCGTTGTTTTATTAGATGAAATTGAAAAAGCACATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGATGGACGCATTACAGATTCACAGGGCCGTACAGTGGACTTTAAAAATACAGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTACTAGATGGATTAGAAGAAGATGGTTCCATTAAAGAGGAATCAAGAGA
CCTTGTAATGGGGCAATTAAGAGGACATTTCCGCCCTGAATTTTTAAACCGTGTGGATGAAATTATTTTATTCAAACCTC
TTACAACGAATGAAATTAAAGGCATTGTTGATAAAATTGTAAAAGAACTACAAGGTCGTCTAGCTGACCGTCACATTACA
GTAGAATTAACAGATGCAGCAAAAGAATTTGTTGTGGAAGCAGGTTTCGACCCAATGTACGGAGCTCGTCCATTAAAACG
ATACGTACAGCGTCAAGTGGAAACGAAATTAGCACGAGAATTAATTGCAGGAACAATTACTGATAATAGTCACGTAGTTG
TTGATGTAGAAAATAACGAGTTAGTCGTTCATGTGAAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(602-768)

AAA lid domain (AAA_lid_9)

(345-447)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(97-148)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(17-68)

ATPase family associated with various cellular activities (AAA) (AAA)

(206-339)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(774-854)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Bacillus subtilis subsp. subtilis str. 168

47.657

100

0.482
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.153

100

0.425
  clpC Lactococcus lactis subsp. cremoris KW2

47.059

82.448

0.388
  clpE Streptococcus pneumoniae Rx1

45.415

79.33

0.36
  clpE Streptococcus pneumoniae D39

45.415

79.33

0.36
  clpE Streptococcus pneumoniae R6

45.415

79.33

0.36
  clpE Streptococcus pneumoniae TIGR4

45.415

79.33

0.36

Multiple sequence alignment