Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RJD14_RS37395 Genome accession   NZ_CP134493
Coordinates   8239688..8240350 (+) Length   220 a.a.
NCBI ID   WP_189724460.1    Uniprot ID   A0ABZ1MFP5
Organism   Streptomyces sp. CGMCC 4.1456     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8234688..8245350
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJD14_RS37370 (RJD14_37370) mug 8235687..8236232 (+) 546 WP_311130153.1 G/U mismatch-specific DNA glycosylase -
  RJD14_RS37375 (RJD14_37375) - 8236237..8236668 (-) 432 WP_311130154.1 hypothetical protein -
  RJD14_RS37380 (RJD14_37380) - 8236738..8237466 (-) 729 WP_311130155.1 ABC transporter permease -
  RJD14_RS37385 (RJD14_37385) - 8237469..8238389 (-) 921 WP_311130156.1 ABC transporter ATP-binding protein -
  RJD14_RS37390 (RJD14_37390) - 8238498..8239673 (+) 1176 WP_311130157.1 histidine kinase -
  RJD14_RS37395 (RJD14_37395) vraR 8239688..8240350 (+) 663 WP_189724460.1 response regulator transcription factor Regulator
  RJD14_RS37400 (RJD14_37400) - 8240440..8241597 (+) 1158 WP_311130158.1 ROK family transcriptional regulator -
  RJD14_RS37405 (RJD14_37405) - 8241664..8242425 (-) 762 WP_311130159.1 GntR family transcriptional regulator -
  RJD14_RS37410 (RJD14_37410) - 8242594..8243478 (-) 885 WP_311130160.1 RNA polymerase sigma-70 factor -
  RJD14_RS37415 (RJD14_37415) - 8243588..8244241 (+) 654 WP_311130529.1 NAD(P)-binding domain-containing protein -
  RJD14_RS37420 (RJD14_37420) - 8244349..8245179 (+) 831 WP_311130161.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23638.25 Da        Isoelectric Point: 4.7792

>NTDB_id=804232 RJD14_RS37395 WP_189724460.1 8239688..8240350(+) (vraR) [Streptomyces sp. CGMCC 4.1456]
MPVTVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRRLRPDVVAMDVRMPLLDGIEATRALLRTVDEPPRI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLIAEGESLLFPASVRQLAAEYGDDGGNRAARAVMERAQLTER
EAEVLRLMARGLSNAEIAARLVVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=804232 RJD14_RS37395 WP_189724460.1 8239688..8240350(+) (vraR) [Streptomyces sp. CGMCC 4.1456]
ATGCCGGTCACCGTTCTCCTCGTCGACGACGAACCCCTGGTACGCGCGGGTCTGCGGGCCGTGCTGGAGGCACAGCCCGA
CATCGAGGTCGTCGGGGAGGCCGCGGACGGGGCGGCGGTGATCCCGCTCGTGCGGCGGCTGCGGCCCGACGTGGTCGCCA
TGGACGTACGGATGCCGCTGCTGGACGGCATCGAGGCCACCCGGGCGCTGCTGCGGACGGTCGACGAGCCGCCGCGGATC
CTGGTGGTGACGACCTTCGAGAACGACGAGTACGTGTACGAGGCGCTGCGGGCCGGGGCCGACGGGTTTCTGCTCAAGCG
GGCCCGGCCGGCCGAGATCGTGCACGCGGTGCGGCTGATCGCCGAGGGCGAGTCGCTGCTGTTCCCGGCCTCGGTGCGGC
AGCTCGCCGCCGAGTACGGCGACGACGGCGGGAACCGCGCGGCGCGGGCCGTGATGGAGCGGGCCCAGCTGACCGAGCGC
GAGGCCGAGGTGCTGCGGCTGATGGCGCGGGGTCTGTCGAACGCGGAGATCGCGGCCCGGCTGGTCGTCGGGACGGAGAC
CGTGAAGTCGCATGTGAGCGCGGTACTGGCGAAGTTGGGGGCGCGGGACCGGACCCAGGCGGTGATCGCCGCGTACGAGT
CGGGGTTCGTGGCACCGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.826

99.091

0.405
  degU Bacillus subtilis subsp. subtilis str. 168

35.965

100

0.373