Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RJD14_RS15745 Genome accession   NZ_CP134493
Coordinates   3443020..3443706 (+) Length   228 a.a.
NCBI ID   WP_184594412.1    Uniprot ID   A0A7W4ZSY7
Organism   Streptomyces sp. CGMCC 4.1456     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3438020..3448706
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJD14_RS15725 (RJD14_15725) - 3438386..3439252 (+) 867 WP_311126918.1 alpha/beta hydrolase -
  RJD14_RS15730 (RJD14_15730) - 3439428..3440429 (+) 1002 WP_311126919.1 alpha/beta hydrolase -
  RJD14_RS15735 (RJD14_15735) - 3440422..3441642 (+) 1221 WP_311126920.1 acyltransferase -
  RJD14_RS15740 (RJD14_15740) - 3441635..3443023 (+) 1389 WP_311126921.1 sensor histidine kinase -
  RJD14_RS15745 (RJD14_15745) vraR 3443020..3443706 (+) 687 WP_184594412.1 response regulator transcription factor Regulator
  RJD14_RS15750 (RJD14_15750) - 3443806..3445143 (+) 1338 WP_311126922.1 histidine kinase -
  RJD14_RS15755 (RJD14_15755) vraR 3445140..3445805 (+) 666 WP_184594416.1 response regulator transcription factor Regulator
  RJD14_RS15760 (RJD14_15760) - 3445875..3447092 (+) 1218 WP_311126923.1 cytochrome P450 -
  RJD14_RS15765 (RJD14_15765) - 3447076..3447300 (-) 225 WP_230529415.1 hypothetical protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24497.16 Da        Isoelectric Point: 4.6905

>NTDB_id=804183 RJD14_RS15745 WP_184594412.1 3443020..3443706(+) (vraR) [Streptomyces sp. CGMCC 4.1456]
MTSGGTGDPIRVLIVDDQAMVRQGFTVLLGIQPDIEVVGEAREGREAIAKAAETAPDVVLMDIRMPGVGGIEATELITAA
HPDIKVLVLTTFDLDEYVYDALRAGASGFLLKDASSEQLAEAVRVVAAGEALLAPVITRKLIAEFSRLDDRPRAPLKERI
GDLTERETEVLALIAQGLSNGEIARHLFVAEQTVKTHVGRILVKLGLRDRTQAAVFAYESGLVRPSGY

Nucleotide


Download         Length: 687 bp        

>NTDB_id=804183 RJD14_RS15745 WP_184594412.1 3443020..3443706(+) (vraR) [Streptomyces sp. CGMCC 4.1456]
ATGACGAGCGGCGGCACCGGCGATCCCATCCGGGTACTCATCGTCGACGACCAGGCGATGGTCCGGCAGGGCTTCACCGT
GCTGCTCGGCATCCAGCCCGACATAGAGGTCGTCGGCGAGGCGCGGGAGGGCCGGGAAGCCATCGCGAAGGCCGCCGAGA
CCGCACCGGACGTCGTCCTCATGGACATCCGCATGCCCGGGGTCGGCGGTATCGAGGCCACCGAGCTGATCACGGCCGCG
CACCCGGACATCAAGGTGCTGGTGCTCACCACCTTCGACCTCGACGAGTACGTGTACGACGCGCTGCGCGCCGGGGCCTC
CGGGTTCCTGCTGAAGGACGCGTCCTCGGAGCAGCTCGCCGAGGCGGTCCGGGTAGTGGCGGCCGGGGAGGCGCTGCTCG
CCCCGGTCATCACCCGCAAGCTGATCGCCGAGTTCTCCCGGCTGGACGACCGGCCCCGAGCCCCGCTCAAGGAACGCATC
GGCGACCTGACCGAGCGGGAGACGGAGGTGCTCGCCCTGATCGCGCAGGGCCTGTCGAACGGGGAGATCGCCCGGCACCT
CTTCGTCGCCGAGCAGACGGTGAAGACCCACGTGGGCCGGATCCTGGTGAAGCTGGGCCTCAGGGACCGGACGCAGGCGG
CGGTGTTCGCGTACGAGTCGGGGCTGGTACGGCCCTCGGGGTACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(12-124)

Bacterial regulatory proteins, luxR family (GerE)

(163-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7W4ZSY7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

47.442

94.298

0.447
  degU Bacillus subtilis subsp. subtilis str. 168

41.256

97.807

0.404