Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RJW53_RS08885 Genome accession   NZ_CP134488
Coordinates   1760097..1760738 (-) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain NLS50     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1755097..1765738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW53_RS08860 (RJW53_08860) comFA/cflA 1755248..1756540 (-) 1293 WP_012774986.1 DEAD/DEAH box helicase Machinery gene
  RJW53_RS08865 (RJW53_08865) - 1756597..1757229 (+) 633 WP_014636235.1 YigZ family protein -
  RJW53_RS08870 (RJW53_08870) cysK 1757322..1758248 (+) 927 WP_012774985.1 cysteine synthase A -
  RJW53_RS08875 (RJW53_08875) - 1758274..1758645 (-) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  RJW53_RS08880 (RJW53_08880) - 1758647..1760047 (-) 1401 WP_024406021.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  RJW53_RS08885 (RJW53_08885) vraR 1760097..1760738 (-) 642 WP_002937025.1 response regulator transcription factor Regulator
  RJW53_RS08890 (RJW53_08890) - 1760710..1761726 (-) 1017 WP_074389315.1 sensor histidine kinase -
  RJW53_RS08895 (RJW53_08895) liaF 1761723..1762418 (-) 696 WP_012774984.1 cell wall-active antibiotics response protein LiaF -
  RJW53_RS08900 (RJW53_08900) stkP 1762839..1764833 (-) 1995 WP_024406019.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  RJW53_RS08905 (RJW53_08905) - 1764833..1765570 (-) 738 WP_012774983.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=804127 RJW53_RS08885 WP_002937025.1 1760097..1760738(-) (vraR) [Streptococcus suis strain NLS50]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=804127 RJW53_RS08885 WP_002937025.1 1760097..1760738(-) (vraR) [Streptococcus suis strain NLS50]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGCCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCGTTAGAGGTTAAACCTGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACTCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413