Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RJW49_RS02090 Genome accession   NZ_CP134477
Coordinates   413273..413914 (+) Length   213 a.a.
NCBI ID   WP_014735510.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS40     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 408273..418914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW49_RS02070 (RJW49_02070) - 408573..409310 (+) 738 WP_014735507.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  RJW49_RS02075 (RJW49_02075) stkP 409310..411304 (+) 1995 WP_074393508.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  RJW49_RS02080 (RJW49_02080) liaF 411629..412288 (+) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  RJW49_RS02085 (RJW49_02085) - 412285..413301 (+) 1017 WP_014735509.1 sensor histidine kinase -
  RJW49_RS02090 (RJW49_02090) vraR 413273..413914 (+) 642 WP_014735510.1 response regulator transcription factor Regulator
  RJW49_RS02095 (RJW49_02095) - 413964..415364 (+) 1401 WP_074393507.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  RJW49_RS02100 (RJW49_02100) - 415366..415737 (+) 372 WP_074393506.1 S1 RNA-binding domain-containing protein -
  RJW49_RS02105 (RJW49_02105) cysK 415763..416689 (-) 927 WP_012774985.1 cysteine synthase A -
  RJW49_RS02110 (RJW49_02110) - 416779..417411 (-) 633 WP_014735512.1 YigZ family protein -
  RJW49_RS02115 (RJW49_02115) comFA/cflA 417468..418760 (+) 1293 WP_074393504.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23832.44 Da        Isoelectric Point: 4.8970

>NTDB_id=803889 RJW49_RS02090 WP_014735510.1 413273..413914(+) (vraR) [Streptococcus suis strain NLS40]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVIVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILVAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=803889 RJW49_RS02090 WP_014735510.1 413273..413914(+) (vraR) [Streptococcus suis strain NLS40]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTATAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGTAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

55.072

97.183

0.535
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.408