Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   RJW49_RS00345 Genome accession   NZ_CP134477
Coordinates   62188..64125 (+) Length   645 a.a.
NCBI ID   WP_014735250.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS40     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 57188..69125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW49_RS00330 (RJW49_00330) - 58062..58999 (-) 938 Protein_45 IS4 family transposase -
  RJW49_RS00335 (RJW49_00335) - 59136..60356 (+) 1221 WP_074393600.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  RJW49_RS00340 (RJW49_00340) - 60547..62070 (+) 1524 WP_014735249.1 Heme/copper-type cytochrome/quinol oxidase subunit 1 -
  RJW49_RS00345 (RJW49_00345) hexB 62188..64125 (+) 1938 WP_014735250.1 DNA mismatch repair endonuclease MutL Machinery gene
  RJW49_RS00350 (RJW49_00350) ruvA 64164..64754 (+) 591 WP_014735251.1 Holliday junction branch migration protein RuvA Machinery gene
  RJW49_RS00355 (RJW49_00355) - 65128..65697 (+) 570 WP_014735252.1 DNA-3-methyladenine glycosylase I -
  RJW49_RS00360 (RJW49_00360) cinA 65734..66915 (+) 1182 WP_074393601.1 competence/damage-inducible protein A Machinery gene
  RJW49_RS00365 (RJW49_00365) recA 66967..68118 (+) 1152 WP_024387809.1 recombinase RecA Machinery gene
  RJW49_RS00370 (RJW49_00370) spx 68354..68752 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  RJW49_RS00375 (RJW49_00375) - 68852..69118 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72851.04 Da        Isoelectric Point: 5.1710

>NTDB_id=803864 RJW49_RS00345 WP_014735250.1 62188..64125(+) (hexB) [Streptococcus suis strain NLS40]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKNQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEALDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPAENK
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=803864 RJW49_RS00345 WP_014735250.1 62188..64125(+) (hexB) [Streptococcus suis strain NLS40]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTTAAAA
TGATTCAAATCACGGATAACGGTGAGGGAATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCTACTAGTAAG
ATAAAAAATCAATCGGATTTGTTTCGTATTCGCACCCTAGGTTTTCGTGGAGAAGCTCTGCCTTCCATTGCTTCTGTCAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCTTT
TGCCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGCTCTGGATTTTCAGATTTCAGGTTACGTTTCCTTGCCA
GAGTTGACTCGCGCCAACCGCAACTACATTTCCATTTTCATCAACGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTATGGCAGTAAGTTGATGGTAGGACGTTTTCCATTGGCAGTGATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTACATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCACTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGCCGAAAATAAA
CCTACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGTGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCACAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAGCAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTTGTCCACAAAATGGATGCCCTCCGTCAAGTTGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATCTGGATGAAGGAAGAGGAGATTGAGTCTGGTATCTACGAGATGTGCGACATGTTGCTTCTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCAATCAAGGCCAACCA
TGCTTTGGATGATTATTCGGCGCGTGATTTACTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCACACGGTC
GCCCAGTCTTAGTGCATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAGGAAAATCACACGAGTTTGCGA
GAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(447-589)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.462

100

0.73