Detailed information NTG0803302

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: P3U19_RS09645
• Genome accession: NZ_CP120128
• Coordinates: 1956793..1957836 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Dog049
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1951793..1962836

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3U19_RS09615 (P3U19_09615)	-	1952215..1953471 (-)	1257	WP_001793428.1	aminopeptidase	-
P3U19_RS09620 (P3U19_09620)	-	1953474..1953674 (-)	201	WP_000180460.1	DUF1128 family protein	-
P3U19_RS09625 (P3U19_09625)	-	1953821..1954285 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
P3U19_RS09630 (P3U19_09630)	-	1954292..1954567 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
P3U19_RS09635 (P3U19_09635)	-	1954845..1956062 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
P3U19_RS09640 (P3U19_09640)	vraR	1956174..1956803 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
P3U19_RS09645 (P3U19_09645)	vraS	1956793..1957836 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
P3U19_RS09650 (P3U19_09650)	liaF	1957833..1958534 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
P3U19_RS09655 (P3U19_09655)	-	1958549..1958935 (-)	387	WP_043044166.1	hypothetical protein	-
P3U19_RS09660 (P3U19_09660)	map	1959152..1959910 (-)	759	WP_000636138.1	type I methionyl aminopeptidase	-
P3U19_RS09665 (P3U19_09665)	-	1960441..1961427 (+)	987	WP_323696056.1	aromatic acid exporter family protein	-
P3U19_RS09670 (P3U19_09670)	-	1961858..1962271 (-)	414	WP_001566709.1	hypothetical protein	-
P3U19_RS09675 (P3U19_09675)	-	1962300..1962410 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=803302 P3U19_RS09645 WP_001017131.1 1956793..1957836(-) (vraS) [Staphylococcus aureus strain Dog049]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=803302 P3U19_RS09645 WP_001017131.1 1956793..1957836(-) (vraS) [Staphylococcus aureus strain Dog049]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1