Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   RJ642_RS10375 Genome accession   NZ_CP134370
Coordinates   2128346..2129002 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain TUM12357     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2123346..2134002
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJ642_RS10340 (RJ642_10320) dcyD 2124225..2125211 (+) 987 WP_310995185.1 D-cysteine desulfhydrase -
  RJ642_RS10345 (RJ642_10325) tcyL 2125226..2125894 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  RJ642_RS10350 (RJ642_10330) tcyN 2125891..2126643 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  RJ642_RS10355 (RJ642_10335) sdiA 2126873..2127595 (+) 723 WP_001152715.1 transcriptional regulator SdiA -
  RJ642_RS10360 (RJ642_10340) yecF 2127663..2127887 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  RJ642_RS10365 (RJ642_10345) yecU 2127874..2128050 (-) 177 WP_000590347.1 protein YecU -
  RJ642_RS10370 (RJ642_10350) - 2128133..2128204 (-) 72 Protein_2027 transcriptional regulator -
  RJ642_RS10375 (RJ642_10355) letA 2128346..2129002 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  RJ642_RS10380 (RJ642_10360) uvrC 2128999..2130831 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  RJ642_RS10385 (RJ642_10365) pgsA 2130888..2131436 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  RJ642_RS10405 (RJ642_10385) yecA 2132086..2132751 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=803098 RJ642_RS10375 WP_000611335.1 2128346..2129002(+) (letA) [Escherichia coli strain TUM12357]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=803098 RJ642_RS10375 WP_000611335.1 2128346..2129002(+) (letA) [Escherichia coli strain TUM12357]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486