Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   P3T86_RS00245 Genome accession   NZ_CP120099
Coordinates   55397..56746 (-) Length   449 a.a.
NCBI ID   WP_207606747.1    Uniprot ID   -
Organism   Staphylococcus nepalensis strain Dog109     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Genomic Context

Location: 50397..61746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3T86_RS00220 (P3T86_00220) - 51478..51681 (-) 204 WP_119521786.1 hypothetical protein -
  P3T86_RS00225 (P3T86_00225) - 52007..52513 (-) 507 WP_107628103.1 DUF1643 domain-containing protein -
  P3T86_RS00230 (P3T86_00230) - 52529..52840 (-) 312 WP_046207795.1 DUF960 family protein -
  P3T86_RS00235 (P3T86_00235) - 52936..53274 (-) 339 WP_011302037.1 SAUGI family uracil-DNA glycosylase inhibitor -
  P3T86_RS00240 (P3T86_00240) ccrB 53748..55376 (-) 1629 WP_071331188.1 cassette chromosome recombinase CcrB Machinery gene
  P3T86_RS00245 (P3T86_00245) ccrA 55397..56746 (-) 1350 WP_207606747.1 cassette chromosome recombinase CcrA Machinery gene
  P3T86_RS00250 (P3T86_00250) - 56938..57213 (-) 276 WP_038679385.1 hypothetical protein -
  P3T86_RS00255 (P3T86_00255) cch1 57284..59074 (-) 1791 WP_207606748.1 cassette chromosome replicative helicase -
  P3T86_RS00260 (P3T86_00260) - 59074..59223 (-) 150 WP_167330439.1 hypothetical protein -
  P3T86_RS00265 (P3T86_00265) - 59406..60398 (-) 993 WP_323702575.1 hypothetical protein -
  P3T86_RS00270 (P3T86_00270) - 60530..60751 (+) 222 WP_323703393.1 GNAT family N-acetyltransferase -
  P3T86_RS00275 (P3T86_00275) - 61247..61594 (-) 348 WP_323702576.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52301.14 Da        Isoelectric Point: 10.2145

>NTDB_id=802925 P3T86_RS00245 WP_207606747.1 55397..56746(-) (ccrA) [Staphylococcus nepalensis strain Dog109]
MKQAMGYLRQSTTKQQSLPAQKQAIKTLAKKHNIQHITFYSDKQSGRTDKRNGYQQITQLIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVSNGIKEKARQGKLITTHAPFGYHYK
RGTFTINKNESPTVIAVFNYYLQGNGYKKITQFLEEDNKLIDRKPYQVRNIIMNPNYCGRVINHYGQYDNMFPSIVSTNM
YEQAQALRSQKQIKRTPSDNQLKQKIKCPYCGSTLTNMTIRKKNHTLRYYVCSRNMNASHFVCEFKGINAPKLETQVLTT
CQDFFQNQQLYLKINDVIQKRIKKQRALETKSTLTQQQLIDKLAKGSIDAETFRKQSQSLLQQSKPTLSINEQQIQRSFE
NVIQQRFTLNMLYPYIDEIHISKNKSLVGIYFKNEPLNIVNQATQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=802925 P3T86_RS00245 WP_207606747.1 55397..56746(-) (ccrA) [Staphylococcus nepalensis strain Dog109]
ATGAAACAAGCAATGGGTTACTTACGTCAAAGTACAACAAAACAACAATCACTTCCGGCACAGAAACAAGCCATCAAGAC
ATTAGCTAAAAAACACAATATTCAACACATCACATTTTATAGTGATAAGCAATCAGGACGCACTGATAAGCGAAACGGTT
ACCAGCAAATTACTCAACTGATTCAACAAGGACAATGTGACGTACTATGTTGCTATCGGCTGAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAACTCATGAAATTGTGCCAAAAATATCATGTTCATATCTTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTTAAACTCAATATTTTCATCAGCTTGGCCGAATTAGAATCTGATAATATTGGCGAAC
AAGTAAGCAACGGGATAAAAGAAAAAGCGCGTCAGGGTAAATTGATAACTACACACGCCCCCTTTGGTTACCACTACAAA
CGTGGTACATTCACGATAAATAAGAATGAATCACCAACGGTAATTGCCGTATTCAATTACTATCTTCAAGGTAATGGCTA
TAAAAAAATTACACAGTTCTTAGAAGAAGATAACAAACTAATAGACCGTAAACCTTATCAAGTACGTAATATTATTATGA
ATCCCAATTACTGTGGTCGTGTTATCAATCACTACGGACAATATGACAACATGTTCCCGTCTATTGTTTCTACAAATATG
TACGAACAAGCGCAAGCTCTACGGTCACAAAAACAAATCAAACGAACACCTTCAGACAATCAACTCAAACAAAAAATCAA
ATGCCCTTATTGCGGATCGACGCTTACCAATATGACAATTAGAAAAAAGAACCATACATTACGTTACTATGTCTGTTCTC
GAAATATGAATGCATCTCATTTTGTCTGTGAATTCAAAGGGATTAATGCGCCAAAACTAGAAACTCAAGTCTTAACTACA
TGTCAGGACTTCTTTCAAAATCAACAACTTTACTTAAAAATCAACGATGTAATTCAAAAAAGGATCAAAAAACAAAGGGC
CCTAGAAACTAAGAGCACACTTACACAACAACAATTGATAGATAAATTAGCTAAAGGATCCATCGATGCAGAAACGTTCA
GAAAACAATCTCAATCGTTACTTCAACAATCAAAACCAACACTATCAATAAATGAGCAACAAATTCAAAGATCATTTGAA
AATGTAATTCAACAACGCTTCACGTTAAACATGTTATACCCATATATTGATGAAATTCATATTTCTAAAAACAAAAGCCT
TGTGGGAATCTATTTCAAAAATGAACCGCTAAACATTGTAAACCAAGCTACGCAATCATCGATTGCTTAA

Domains

Predicted by InterproScan.

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-250)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

81.069

100

0.811
  ccrA Staphylococcus aureus N315

76.169

100

0.762