Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   RJ646_RS21565 Genome accession   NZ_CP134358
Coordinates   4519737..4522559 (+) Length   940 a.a.
NCBI ID   WP_000357740.1    Uniprot ID   Q3YUS6
Organism   Escherichia coli strain TUM13936     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4514737..4527559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJ646_RS21540 (RJ646_21540) soxR 4515675..4516139 (-) 465 WP_000412428.1 redox-sensitive transcriptional activator SoxR -
  RJ646_RS21545 (RJ646_21545) soxS 4516225..4516548 (+) 324 WP_000019358.1 superoxide response transcriptional regulator SoxS -
  RJ646_RS21550 (RJ646_21550) pdeC 4516551..4518137 (-) 1587 WP_045177302.1 c-di-GMP phosphodiesterase PdeC -
  RJ646_RS21555 (RJ646_21555) yjcB 4518566..4518847 (+) 282 WP_001295689.1 YjcB family protein -
  RJ646_RS21560 (RJ646_21560) ssb 4518946..4519482 (-) 537 WP_000168305.1 single-stranded DNA-binding protein SSB1 Machinery gene
  RJ646_RS21565 (RJ646_21565) uvrA 4519737..4522559 (+) 2823 WP_000357740.1 excinuclease ABC subunit UvrA Machinery gene
  RJ646_RS21570 (RJ646_21570) yjbR 4522594..4522950 (-) 357 WP_000155657.1 MmcQ/YjbR family DNA-binding protein -
  RJ646_RS21575 (RJ646_21575) yjbQ 4522954..4523370 (-) 417 WP_000270375.1 secondary thiamine-phosphate synthase enzyme YjbQ -
  RJ646_RS21580 (RJ646_21580) aphA 4523481..4524194 (-) 714 WP_001226928.1 acid phosphatase AphA -
  RJ646_RS21585 (RJ646_21585) - 4524612..4524834 (+) 223 Protein_4223 hypothetical protein -
  RJ646_RS21590 (RJ646_21590) - 4524864..4525115 (+) 252 WP_122986486.1 hypothetical protein -
  RJ646_RS21595 (RJ646_21595) tyrB 4525339..4526532 (-) 1194 WP_276270054.1 aromatic amino acid transaminase -

Sequence

Protein


Download         Length: 940 a.a.        Molecular weight: 103867.54 Da        Isoelectric Point: 6.6066

>NTDB_id=802873 RJ646_RS21565 WP_000357740.1 4519737..4522559(+) (uvrA) [Escherichia coli strain TUM13936]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide


Download         Length: 2823 bp        

>NTDB_id=802873 RJ646_RS21565 WP_000357740.1 4519737..4522559(+) (uvrA) [Escherichia coli strain TUM13936]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAGCTCAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAAAAGCCGGACGTCGATCATATTGAGGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGTTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTTTGTTGTTCGCCCGCGTCGGCGAACCGCGCTGTCCGGACCACGACGTCCCGCTGGCGGCGCAAACCGTCAGCC
AGATGGTGGATAACGTGCTGTCGCAGCCGGAAGGCAAGCGTCTGATGCTGCTCGCGCCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAGAACCTGGCAAGCCAGGGTTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAACTGCAAAAGAAACATACCATTGAAGTGGTGGTTGATCGCTTCAAGGTGCGTGACGATCTTA
CCCAACGTCTTGCCGAGTCGTTTGAAACCGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTTGCGGATATGGACGACCCG
AAAGCGGAAGAGCTGCTGTTCTCCGCTAATTTCGCCTGCCCAATTTGCGGCTACAGTATGCGTGAACTGGAGCCGCGACT
GTTTTCGTTTAACAACCCGGCAGGGGCCTGCCCGACCTGTGACGGCCTTGGCGTACAGCAATATTTCGATCCTGACCGCG
TGATCCAGAATCCGGAACTGTCGCTGGCAGGTGGTGCGATCCGTGGCTGGGATCGCCGCAACTTCTATTATTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCGTGGGGCAGCCTGAGCGCGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAACATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACGGAGTCCAGCGCGGTACGCGAAGAATTAGCCAAGTTT
ATCAGTAATCGTCCGTGTGCCAGCTGCGAAGGGACGCGTCTGCGTCGGGAAGCGCGCCACGTGTATGTCGAGAATACGCC
GCTGCCCGCCATCTCCGACATGAGCATTGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCAGGTCAGCGGGCGA
AGATTGCGGAAAAAATCCTTAAAGAGATCGGCGATCGTCTGAAATTCCTCGTTAACGTCGGCCTGAATTACCTGACACTT
TCCCGCTCGGCAGAAACGCTTTCTGGCGGTGAAGCACAGCGTATTCGTCTGGCGAGCCAGATTGGTGCGGGCCTGGTTGG
TGTTATGTATGTACTGGACGAGCCGTCTATCGGCCTGCACCAGCGCGATAACGAGCGCCTGTTGGGTACACTTATCCATC
TGCGCGATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCCGCTGACCATGTGATCGATATC
GGTCCTGGTGCAGGTGTACATGGCGGTGAAGTGGTCGCAGAAGGTCCGCTGGAAGCGATTATGGCGGTGCCGGAGTCGTT
GACCGGACAGTACATGAGCGGTAAACGCAAGATTGAAGTGCCGAAGAAACGCGTTCCGGCGAATCCGGAAAAAGTACTTA
AGCTGACTGGCGCACGCGGCAACAACCTGAAAGACGTGACGCTAACGCTGCCAGTCGGTCTGTTTACCTGCATCACAGGG
GTTTCAGGTTCCGGTAAATCGACGCTGATTAACGACACACTGTTCCCGATTGCCCAACGCCAGTTGAATGGTGCGACCAT
CGCCGAACCGGCACCGTATCGCGATATTCAGGGGCTGGAGCATTTCGATAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCGCGTTCTAACCCGGCGACCTATACCGGCGTGTTTACACCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGCGGCTATACGCCGGGACGTTTCAGCTTTAACGTCCGTGGCGGACGCTGCGAGGCCTGTCAGGGCGATGG
CGTGATCAAAGTGGAGATGCACTTCCTGCCGGATATCTACGTGCCGTGCGACCAGTGCAAAGGTAAACGCTATAACCGTG
AAACGCTGGAGATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCGGTGCCAGCTCTGGCGCGTAAGCTGCAAACGTTGATGGACGTTGGCCTGACGTACATTCGCCTGGGGCAGTCCGC
AACCACACTTTCTGGTGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACACTGT
ATATTCTCGACGAGCCGACCACCGGTTTGCACTTCGCCGATATTCAGCAACTGCTCGACGTGCTGCATAAACTGCGCGAT
CAGGGCAATACCATCGTGGTGATTGAGCACAATCTCGACGTGATCAAAACTGCTGACTGGATTGTCGACCTGGGTCCGGA
AGGCGGCAGTGGCGGCGGCGAGATCCTCGTCTCCGGTACACCAGAAACCGTCGCGGAGTGCGAAGCATCACACACGGCAC
GCTTCCTTAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(290-399)

ABC transporter (ABC_tran)

(806-860)

UvrA interaction domain (UvrA_inter)

(130-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YUS6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.37

100

0.576
  uvrA Streptococcus pneumoniae TIGR4

57.37

100

0.576
  uvrA Streptococcus pneumoniae D39

57.37

100

0.576