Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   RJ646_RS09620 Genome accession   NZ_CP134358
Coordinates   2012800..2013456 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain TUM13936     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2007800..2018456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJ646_RS09585 (RJ646_09585) dcyD 2008679..2009665 (+) 987 WP_310984128.1 D-cysteine desulfhydrase -
  RJ646_RS09590 (RJ646_09590) tcyL 2009680..2010348 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  RJ646_RS09595 (RJ646_09595) tcyN 2010345..2011097 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  RJ646_RS09600 (RJ646_09600) sdiA 2011327..2012049 (+) 723 WP_024231281.1 transcriptional regulator SdiA -
  RJ646_RS09605 (RJ646_09605) yecF 2012117..2012341 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  RJ646_RS09610 (RJ646_09610) yecU 2012328..2012504 (-) 177 WP_000590347.1 protein YecU -
  RJ646_RS09615 (RJ646_09615) - 2012587..2012658 (-) 72 Protein_1874 transcriptional regulator -
  RJ646_RS09620 (RJ646_09620) letA 2012800..2013456 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  RJ646_RS09625 (RJ646_09625) uvrC 2013453..2015285 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  RJ646_RS09630 (RJ646_09630) pgsA 2015342..2015890 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  RJ646_RS09650 (RJ646_09650) - 2016474..2017490 (-) 1017 WP_021560873.1 tyrosine-type recombinase/integrase -
  RJ646_RS09655 (RJ646_09655) - 2017459..2017722 (-) 264 WP_112925015.1 DUF4224 domain-containing protein -
  RJ646_RS09665 (RJ646_09665) - 2017932..2018114 (-) 183 WP_000916333.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=802844 RJ646_RS09620 WP_000611328.1 2012800..2013456(+) (letA) [Escherichia coli strain TUM13936]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=802844 RJ646_RS09620 WP_000611328.1 2012800..2013456(+) (letA) [Escherichia coli strain TUM13936]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482