Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RI578_RS30460 Genome accession   NZ_CP134203
Coordinates   6657333..6657974 (+) Length   213 a.a.
NCBI ID   WP_210964716.1    Uniprot ID   -
Organism   Streptomyces sp. BB1-1-1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6652333..6662974
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RI578_RS30440 (RI578_30440) - 6653135..6653851 (-) 717 WP_310874063.1 transglycosylase SLT domain-containing protein -
  RI578_RS30445 (RI578_30445) - 6654239..6655282 (-) 1044 WP_310874064.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  RI578_RS30450 (RI578_30450) - 6655279..6655977 (-) 699 WP_310874065.1 SDR family NAD(P)-dependent oxidoreductase -
  RI578_RS30455 (RI578_30455) - 6656195..6657340 (+) 1146 WP_310874066.1 GAF domain-containing sensor histidine kinase -
  RI578_RS30460 (RI578_30460) vraR 6657333..6657974 (+) 642 WP_210964716.1 response regulator transcription factor Regulator
  RI578_RS30465 (RI578_30465) chpE 6658141..6658386 (+) 246 WP_219188938.1 chaplin ChpE -
  RI578_RS30470 (RI578_30470) - 6658731..6659519 (-) 789 WP_310874067.1 hypothetical protein -
  RI578_RS30475 (RI578_30475) - 6659672..6660469 (+) 798 WP_310874068.1 ABC transporter ATP-binding protein -
  RI578_RS30480 (RI578_30480) - 6660526..6660957 (+) 432 WP_310874069.1 NfeD family protein -
  RI578_RS30485 (RI578_30485) - 6661126..6662076 (+) 951 WP_310874070.1 SPFH domain-containing protein -
  RI578_RS30490 (RI578_30490) - 6662145..6662651 (-) 507 WP_310874071.1 HNH endonuclease -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23055.29 Da        Isoelectric Point: 5.1644

>NTDB_id=802706 RI578_RS30460 WP_210964716.1 6657333..6657974(+) (vraR) [Streptomyces sp. BB1-1-1]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVDRAEELKPDVILMDVKMPGMDGVDALRRLRELDNRAR
VLVVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEENNSGQGRAGALTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVTG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=802706 RI578_RS30460 WP_210964716.1 6657333..6657974(+) (vraR) [Streptomyces sp. BB1-1-1]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGACCACCAGGTGGTCCGCCGGGGCCTGCGCACCTTCCTGGAGGTGCA
GGACGACATCGAGGTGGTGGGCGAGGCCGCCGACGGAGCCGAGGGCGTCGACCGCGCCGAGGAACTGAAACCCGACGTGA
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGCGTCGACGCGCTGCGCAGACTCCGCGAGCTGGACAACCGCGCGCGC
GTGCTGGTCGTCACCAGCTTCACCGAGCAGCGCACCGTCGTCCCGGCCCTGCGGGCGGGCGCGGCCGGTTACGTCTACAA
GGACGTCGACCCCGACGCGCTGGCGGGCGCCATCCGCTCCGTCCACGCCGGCCACATCCTGCTCCAGCCCGAGGTCGCGG
GCGCCCTGCTGTCCCAGGAGGAGAACAACTCCGGGCAGGGCAGAGCGGGTGCCCTCACGGAGCGGGAGCGCGAGGTGCTG
GGCCTGATAGCGGACGGCCGCTCCAACCGGGAGATCGCGCGCGCCCTCGTCCTCTCCGAGAAGACGGTGAAGACCCACGT
CTCGAACATCCTGATGAAACTCGATCTGGCGGACCGCACCCAGGCCGCACTGTGGGCCGTGCGCCACGGTGTGACCGGCT
GA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-206)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.919

99.061

0.465
  degU Bacillus subtilis subsp. subtilis str. 168

37.557

100

0.39