Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RIU97_RS22460 Genome accession   NZ_CP134201
Coordinates   4900945..4901568 (-) Length   207 a.a.
NCBI ID   WP_361759020.1    Uniprot ID   -
Organism   Streptomyces sp. 147326     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4895945..4906568
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIU97_RS22425 (RIU97_22365) - 4896158..4896316 (+) 159 WP_404959381.1 hypothetical protein -
  RIU97_RS22430 (RIU97_22370) - 4896365..4897270 (+) 906 WP_404959382.1 aminoglycoside phosphotransferase family protein -
  RIU97_RS22435 (RIU97_22375) - 4897316..4897789 (+) 474 WP_404959383.1 GNAT family N-acetyltransferase -
  RIU97_RS22440 (RIU97_22380) - 4897804..4898799 (-) 996 WP_404962900.1 zinc-binding dehydrogenase -
  RIU97_RS22445 (RIU97_22385) - 4898879..4899553 (+) 675 WP_404959384.1 pentapeptide repeat-containing protein -
  RIU97_RS22450 (RIU97_22390) - 4899483..4899947 (-) 465 WP_404959385.1 hypothetical protein -
  RIU97_RS22455 (RIU97_22395) - 4900265..4900768 (-) 504 WP_030718823.1 hypothetical protein -
  RIU97_RS22460 (RIU97_22400) vraR 4900945..4901568 (-) 624 WP_361759020.1 response regulator transcription factor Regulator
  RIU97_RS22465 (RIU97_22405) - 4901565..4902728 (-) 1164 WP_404959386.1 sensor histidine kinase -
  RIU97_RS22470 (RIU97_22410) - 4903077..4903646 (+) 570 WP_404959387.1 heme-binding protein -
  RIU97_RS22475 (RIU97_22415) - 4903688..4905136 (+) 1449 WP_404959388.1 M1 family metallopeptidase -
  RIU97_RS22480 (RIU97_22420) - 4905149..4905673 (-) 525 WP_404959389.1 GNAT family N-acetyltransferase -
  RIU97_RS22485 (RIU97_22425) - 4905837..4906412 (-) 576 WP_030718836.1 TerD family protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 21876.11 Da        Isoelectric Point: 5.6407

>NTDB_id=802495 RIU97_RS22460 WP_361759020.1 4900945..4901568(-) (vraR) [Streptomyces sp. 147326]
MTTILLCDDHVVVRAGLLALLGSEPDIEVLGEAGSGEEAVALAAKLRPDVVLMDLQLGEGIDGVEATRRITAAPNPPHVL
VLTTYDTDADITRAIGAGATGYLLKAERPEELFAAIHSAAQGRTTLSAPVASRVMAHMRGTRPTLTDRELDILGQLARGL
GNRDIARALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLPS

Nucleotide


Download         Length: 624 bp        

>NTDB_id=802495 RIU97_RS22460 WP_361759020.1 4900945..4901568(-) (vraR) [Streptomyces sp. 147326]
ATGACGACGATCCTGCTCTGCGACGACCACGTGGTGGTCCGCGCCGGCCTGCTCGCCCTCCTCGGCAGCGAGCCGGACAT
CGAGGTCCTCGGCGAGGCGGGCAGCGGCGAGGAGGCGGTGGCCCTGGCCGCCAAACTCCGCCCCGACGTGGTCCTCATGG
ACCTCCAGCTCGGCGAGGGCATCGACGGGGTGGAAGCCACCCGCCGCATCACCGCCGCCCCCAACCCGCCGCACGTCCTG
GTCCTCACCACGTACGACACCGACGCGGACATCACGCGGGCCATCGGCGCGGGCGCCACCGGCTACCTCCTGAAGGCCGA
GCGCCCGGAGGAGCTCTTCGCCGCCATCCACTCGGCCGCGCAGGGCCGCACCACCCTGTCCGCGCCGGTCGCCAGCCGCG
TGATGGCCCACATGCGCGGTACCCGCCCCACGCTGACCGACCGCGAGCTGGACATCCTCGGCCAGCTGGCCCGCGGCCTC
GGCAACCGCGACATCGCCCGCGCCCTGTTCATCAGCGAAGCCACGGTCAAGACGCACCTGGGCCGCATCTACGACAAACT
CGGCGTCGACACCCGCGCGGGCGCGGTGTCAGTGGCGAAGGAACAACGCCTCCTCCCTTCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(144-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.537

99.034

0.382
  degU Bacillus subtilis subsp. subtilis str. 168

34.562

100

0.362