Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   Q2K21_RS21625 Genome accession   NZ_CP134053
Coordinates   4987325..4987999 (+) Length   224 a.a.
NCBI ID   WP_310773504.1    Uniprot ID   A0ABV7SKD2
Organism   Streptomyces sp. CGMCC 4.7035     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4982325..4992999
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q2K21_RS21605 (Q2K21_21605) - 4983045..4984589 (+) 1545 WP_310773493.1 alpha/beta fold hydrolase -
  Q2K21_RS21610 (Q2K21_21610) - 4985016..4985588 (+) 573 WP_310773495.1 helix-turn-helix domain-containing protein -
  Q2K21_RS21615 (Q2K21_21615) - 4985585..4986028 (+) 444 WP_310773499.1 transposase -
  Q2K21_RS21620 (Q2K21_21620) - 4986186..4987328 (+) 1143 WP_310773501.1 histidine kinase -
  Q2K21_RS21625 (Q2K21_21625) vraR 4987325..4987999 (+) 675 WP_310773504.1 response regulator transcription factor Regulator
  Q2K21_RS21630 (Q2K21_21630) - 4988185..4988601 (+) 417 WP_310773506.1 hypothetical protein -
  Q2K21_RS21635 (Q2K21_21635) - 4988634..4989398 (+) 765 WP_310781154.1 ABC transporter ATP-binding protein -
  Q2K21_RS21640 (Q2K21_21640) - 4989395..4992016 (+) 2622 WP_310773508.1 FtsX-like permease family protein -
  Q2K21_RS21645 (Q2K21_21645) - 4992271..4992849 (-) 579 WP_310773509.1 ATP-binding protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 24009.73 Da        Isoelectric Point: 4.7115

>NTDB_id=802022 Q2K21_RS21625 WP_310773504.1 4987325..4987999(+) (vraR) [Streptomyces sp. CGMCC 4.7035]
MNEMSGPIRVVVVDDQPLIRAGFAMVLAAQSDIEVVGEAENGADALRLLAATKADVVIMDIRMPVMDGVEATRRLTGLPE
APRVLVLTTFDTDEDAFAALQAGASGFLLKNTPPQEVVTAIRVVAGGESVVAPRITRQLLDRFAGKLDPSPRHDARLDLL
TTRERDVLGLIAEGLSNSEIAARLFIAEATVKTHFGKILTKLDLRDRVQAVIFAYDVGLVSPAS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=802022 Q2K21_RS21625 WP_310773504.1 4987325..4987999(+) (vraR) [Streptomyces sp. CGMCC 4.7035]
ATGAATGAGATGAGCGGGCCGATCCGTGTCGTCGTGGTGGACGACCAGCCACTGATCCGGGCGGGATTCGCCATGGTGCT
GGCCGCGCAGAGTGACATCGAGGTCGTGGGCGAGGCGGAGAACGGCGCGGACGCCCTGAGGCTGCTGGCAGCCACCAAGG
CCGATGTCGTCATCATGGACATCCGCATGCCCGTCATGGACGGGGTCGAGGCGACGCGCCGATTGACCGGACTCCCGGAA
GCCCCCCGGGTGCTGGTGCTCACCACCTTCGACACCGATGAGGACGCCTTCGCCGCACTGCAGGCGGGAGCGAGTGGCTT
CCTGCTGAAGAACACCCCACCGCAGGAAGTCGTGACGGCGATCCGTGTCGTGGCGGGCGGCGAGTCCGTCGTGGCCCCGC
GCATCACCCGCCAGCTCCTGGACCGGTTCGCGGGCAAGCTGGACCCTTCGCCCCGCCACGACGCACGGCTGGACCTGTTG
ACCACGCGCGAACGGGACGTGCTCGGGCTGATAGCCGAGGGCCTCTCCAACAGTGAGATCGCCGCTCGCCTGTTCATCGC
CGAGGCGACCGTGAAGACCCACTTCGGAAAGATCCTCACCAAGCTGGACCTGCGCGACCGCGTGCAGGCCGTCATCTTCG
CCTACGACGTGGGCCTCGTCAGCCCCGCGAGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(10-122)

Bacterial regulatory proteins, luxR family (GerE)

(159-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.187

95.536

0.384
  degU Bacillus subtilis subsp. subtilis str. 168

37.5

100

0.375