Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   Q2K21_RS06870 Genome accession   NZ_CP134053
Coordinates   1639427..1640068 (-) Length   213 a.a.
NCBI ID   WP_310767018.1    Uniprot ID   A0ABV7SHB1
Organism   Streptomyces sp. CGMCC 4.7035     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1634427..1645068
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q2K21_RS06850 (Q2K21_06850) atpD 1634745..1636181 (+) 1437 WP_310767007.1 F0F1 ATP synthase subunit beta -
  Q2K21_RS06855 (Q2K21_06855) - 1636418..1636792 (+) 375 WP_310767009.1 F0F1 ATP synthase subunit epsilon -
  Q2K21_RS06860 (Q2K21_06860) - 1636956..1637402 (+) 447 WP_310767012.1 DUF2550 domain-containing protein -
  Q2K21_RS06865 (Q2K21_06865) - 1637483..1639309 (-) 1827 WP_310767015.1 glycoside hydrolase family 18 chitinase -
  Q2K21_RS06870 (Q2K21_06870) vraR 1639427..1640068 (-) 642 WP_310767018.1 response regulator transcription factor Regulator
  Q2K21_RS06875 (Q2K21_06875) - 1640065..1641236 (-) 1172 Protein_1355 sensor histidine kinase -
  Q2K21_RS06880 (Q2K21_06880) - 1641837..1642433 (-) 597 WP_310767021.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
  Q2K21_RS06885 (Q2K21_06885) - 1642447..1643196 (-) 750 WP_310767025.1 ABC transporter permease -
  Q2K21_RS06890 (Q2K21_06890) - 1643219..1644001 (-) 783 WP_310767027.1 ATP-binding cassette domain-containing protein -
  Q2K21_RS06895 (Q2K21_06895) - 1644082..1644723 (+) 642 WP_310767029.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22686.37 Da        Isoelectric Point: 4.6549

>NTDB_id=801992 Q2K21_RS06870 WP_310767018.1 1639427..1640068(-) (vraR) [Streptomyces sp. CGMCC 4.7035]
MIRVLVAEDQAAVRAGLVLILRSAPDIDVVGEAADGERAVALARELRPDLVLMDVQMPCLDGVSATRQIVVERLADVLVL
TTFDLDEYVFGALRAGAAGFLLKNTEAKDLIAAVRTVAGGEGLIAPAVTRRLIAEFAAGPVREPAADQSALEVLTRRERE
VLSCLGEGLSNAEIALRLEMAEATVKTHVSRLLGKLELRNRAQAAVMAQELGL

Nucleotide


Download         Length: 642 bp        

>NTDB_id=801992 Q2K21_RS06870 WP_310767018.1 1639427..1640068(-) (vraR) [Streptomyces sp. CGMCC 4.7035]
ATGATCCGCGTGCTCGTCGCCGAGGACCAGGCCGCCGTGCGCGCCGGGCTGGTCCTCATCCTGCGCAGCGCGCCCGACAT
CGACGTGGTCGGGGAGGCGGCGGACGGCGAGCGGGCGGTGGCGCTCGCCCGTGAGCTGCGGCCGGACCTGGTCCTGATGG
ATGTTCAGATGCCGTGCCTGGACGGGGTCTCGGCGACCCGGCAGATCGTCGTGGAGCGCCTCGCCGACGTGCTGGTGCTC
ACCACGTTCGACCTCGACGAGTACGTGTTCGGGGCGCTGCGGGCGGGCGCGGCAGGGTTCCTGCTGAAGAACACGGAGGC
GAAGGATCTGATCGCCGCCGTGCGGACGGTGGCGGGCGGCGAGGGGCTGATCGCGCCGGCGGTGACGCGGCGGCTGATCG
CGGAGTTCGCCGCCGGGCCCGTCCGGGAGCCGGCGGCCGACCAGTCGGCCCTGGAGGTACTGACGCGACGCGAGCGCGAG
GTGCTGTCCTGTCTCGGCGAGGGGCTCTCCAACGCCGAGATCGCCCTTCGCCTGGAGATGGCGGAGGCCACCGTGAAGAC
CCACGTCAGCCGGCTCCTCGGCAAGCTGGAGCTGCGCAACCGGGCCCAAGCAGCCGTGATGGCACAGGAGTTGGGACTCT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.056

100

0.423
  degU Bacillus subtilis subsp. subtilis str. 168

38.288

100

0.399