Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   Q2K21_RS02515 Genome accession   NZ_CP134053
Coordinates   584495..585163 (-) Length   222 a.a.
NCBI ID   WP_310763659.1    Uniprot ID   A0ABV7SLC0
Organism   Streptomyces sp. CGMCC 4.7035     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 579495..590163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q2K21_RS02500 (Q2K21_02500) - 580269..581072 (+) 804 WP_310763654.1 class I SAM-dependent methyltransferase -
  Q2K21_RS02505 (Q2K21_02505) - 581090..582634 (+) 1545 WP_310763656.1 glycosyltransferase family 39 protein -
  Q2K21_RS02510 (Q2K21_02510) - 582767..584185 (+) 1419 WP_310763657.1 MFS transporter -
  Q2K21_RS02515 (Q2K21_02515) vraR 584495..585163 (-) 669 WP_310763659.1 response regulator transcription factor Regulator
  Q2K21_RS02520 (Q2K21_02520) - 585160..586425 (-) 1266 WP_386276156.1 histidine kinase -
  Q2K21_RS02525 (Q2K21_02525) - 586483..587334 (-) 852 WP_310763664.1 ABC transporter permease -
  Q2K21_RS02530 (Q2K21_02530) - 587331..588269 (-) 939 WP_310763666.1 ATP-binding cassette domain-containing protein -
  Q2K21_RS02535 (Q2K21_02535) - 588541..589374 (+) 834 WP_310763668.1 hypothetical protein -
  Q2K21_RS02540 (Q2K21_02540) - 589527..589823 (+) 297 WP_310763670.1 hypothetical protein -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24024.58 Da        Isoelectric Point: 6.5018

>NTDB_id=801979 Q2K21_RS02515 WP_310763659.1 584495..585163(-) (vraR) [Streptomyces sp. CGMCC 4.7035]
MTTVLIVDDQPLQRYGFRMLLDSVPETDVVGEAAHGTEAVRKAAELRPDVVLMDVRMPGMDGIEATRRIVAAGDRSRVLV
LTTFDLDEYVYAALRAGASGFLLKDARPEELLAGIRAVAAGDAVIAPALTRRLLHEFARLVPPHADGSAEDPRLASLTDR
EREILVAIGKGWSNGEIAARFVLSESTVKTHVGRVLSKIGARDRIQAVIFAYDHGLARPHAG

Nucleotide


Download         Length: 669 bp        

>NTDB_id=801979 Q2K21_RS02515 WP_310763659.1 584495..585163(-) (vraR) [Streptomyces sp. CGMCC 4.7035]
ATGACCACCGTGCTCATCGTGGACGACCAGCCGCTCCAGCGATACGGCTTCCGCATGCTCCTCGACTCCGTACCCGAGAC
GGACGTGGTCGGCGAGGCCGCGCACGGAACCGAGGCCGTGCGCAAGGCCGCCGAACTCCGCCCCGACGTCGTGCTCATGG
ACGTCCGTATGCCGGGCATGGACGGCATCGAGGCCACACGCCGTATCGTCGCCGCCGGCGACCGTTCCCGGGTCCTCGTC
CTGACCACCTTCGACCTCGACGAGTACGTTTATGCGGCCCTGCGCGCAGGGGCCAGCGGCTTCCTGCTCAAGGACGCCCG
TCCCGAGGAACTCCTCGCGGGCATCCGTGCCGTGGCCGCCGGGGACGCCGTGATCGCCCCCGCCCTCACCCGCCGCCTGC
TGCACGAATTCGCCCGGCTCGTGCCGCCCCACGCCGACGGCTCCGCCGAGGACCCGAGGCTGGCCTCCCTCACCGACCGC
GAACGCGAAATCCTCGTCGCCATCGGCAAGGGCTGGTCCAACGGCGAGATCGCCGCCCGCTTCGTGCTGTCGGAATCCAC
GGTGAAGACCCATGTCGGCCGCGTCCTGTCCAAGATCGGCGCCCGCGACCGCATCCAGGCGGTGATCTTCGCCTACGACC
ACGGCCTGGCTCGGCCTCACGCGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(156-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.07

96.847

0.378
  degU Bacillus subtilis subsp. subtilis str. 168

38.182

99.099

0.378