Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   RHN94_RS09615 Genome accession   NZ_CP133811
Coordinates   1959879..1960535 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EC2001     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1954879..1965535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RHN94_RS09580 (RHN94_09555) dcyD 1955758..1956744 (+) 987 WP_001128227.1 D-cysteine desulfhydrase -
  RHN94_RS09585 (RHN94_09560) tcyL 1956759..1957427 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  RHN94_RS09590 (RHN94_09565) tcyN 1957424..1958176 (+) 753 WP_001273015.1 L-cystine ABC transporter ATP-binding protein TcyN -
  RHN94_RS09595 (RHN94_09570) sdiA 1958406..1959128 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  RHN94_RS09600 (RHN94_09575) yecF 1959196..1959420 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  RHN94_RS09605 (RHN94_09580) yecU 1959407..1959583 (-) 177 WP_000590344.1 protein YecU -
  RHN94_RS09610 (RHN94_09585) - 1959621..1959737 (-) 117 WP_001302039.1 hypothetical protein -
  RHN94_RS09615 (RHN94_09590) letA 1959879..1960535 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  RHN94_RS09620 (RHN94_09595) uvrC 1960532..1962364 (+) 1833 WP_001283412.1 excinuclease ABC subunit UvrC Machinery gene
  RHN94_RS09625 (RHN94_09600) pgsA 1962421..1962969 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  RHN94_RS09645 (RHN94_09620) yecA 1963619..1964284 (+) 666 WP_000847876.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=800993 RHN94_RS09615 WP_000611328.1 1959879..1960535(+) (letA) [Escherichia coli strain EC2001]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=800993 RHN94_RS09615 WP_000611328.1 1959879..1960535(+) (letA) [Escherichia coli strain EC2001]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482