Detailed information NTG0800287

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: P1X13_RS03465
• Genome accession: NZ_CP119678
• Coordinates: 694553..695782 (+)
• Length: 409 a.a.
• NCBI ID: WP_009880296.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1004
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 689553..700782

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1X13_RS03440 (P1X13_03440)	-	690169..691446 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
P1X13_RS03445 (P1X13_03445)	-	691433..692608 (-)	1176	WP_010922171.1	hydroxymethylglutaryl-CoA synthase	-
P1X13_RS03450 (P1X13_03450)	-	692817..693656 (+)	840	WP_002990167.1	thymidylate synthase	-
P1X13_RS03455 (P1X13_03455)	-	693736..694233 (+)	498	WP_002984955.1	dihydrofolate reductase	-
P1X13_RS03460 (P1X13_03460)	-	694253..694423 (+)	171	WP_002990165.1	hypothetical protein	-
P1X13_RS03465 (P1X13_03465)	clpX	694553..695782 (+)	1230	WP_009880296.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
P1X13_RS03470 (P1X13_03470)	yihA	695792..696391 (+)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
P1X13_RS03475 (P1X13_03475)	-	696539..697282 (+)	744	WP_002984942.1	hypothetical protein	-
P1X13_RS03480 (P1X13_03480)	-	697341..699258 (-)	1918	Protein_638	ATP-dependent Clp protease ATP-binding subunit	-
P1X13_RS03485 (P1X13_03485)	rpiA	699640..700323 (+)	684	WP_009881270.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45020.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=800287 P1X13_RS03465 WP_009880296.1 694553..695782(+) (clpX) [Streptococcus pyogenes strain 1004]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=800287 P1X13_RS03465 WP_009880296.1 694553..695782(+) (clpX) [Streptococcus pyogenes strain 1004]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTTGAATTAGAATTTGATAA
AGCAGCTCTTGAAGCTATCGCAACTAAAGCGATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CAATGCTTGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575