Detailed information NTG0800038

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: P1Y72_RS00825
• Genome accession: NZ_CP119599
• Coordinates: 177260..178489 (+)
• Length: 409 a.a.
• NCBI ID: WP_009880296.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1133
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 172260..183489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1Y72_RS00800 (P1Y72_00800)	-	172876..174153 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
P1Y72_RS00805 (P1Y72_00805)	-	174140..175315 (-)	1176	WP_010922171.1	hydroxymethylglutaryl-CoA synthase	-
P1Y72_RS00810 (P1Y72_00810)	-	175524..176363 (+)	840	WP_002990167.1	thymidylate synthase	-
P1Y72_RS00815 (P1Y72_00815)	-	176443..176940 (+)	498	WP_002984955.1	dihydrofolate reductase	-
P1Y72_RS00820 (P1Y72_00820)	-	176960..177130 (+)	171	WP_002990165.1	hypothetical protein	-
P1Y72_RS00825 (P1Y72_00825)	clpX	177260..178489 (+)	1230	WP_009880296.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
P1Y72_RS00830 (P1Y72_00830)	yihA	178499..179098 (+)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
P1Y72_RS00835 (P1Y72_00835)	-	179246..179989 (+)	744	WP_002984942.1	hypothetical protein	-
P1Y72_RS00840 (P1Y72_00840)	-	180048..181965 (-)	1918	Protein_166	ATP-dependent Clp protease ATP-binding subunit	-
P1Y72_RS00845 (P1Y72_00845)	rpiA	182347..183030 (+)	684	WP_009881270.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45020.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=800038 P1Y72_RS00825 WP_009880296.1 177260..178489(+) (clpX) [Streptococcus pyogenes strain 1133]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=800038 P1Y72_RS00825 WP_009880296.1 177260..178489(+) (clpX) [Streptococcus pyogenes strain 1133]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTTGAATTAGAATTTGATAA
AGCAGCTCTTGAAGCTATCGCAACTAAAGCGATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CAATGCTTGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575