Detailed information NTG0800011

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: P1K34_RS03525
• Genome accession: NZ_CP119598
• Coordinates: 706926..708155 (+)
• Length: 409 a.a.
• NCBI ID: WP_009880296.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1042
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 701926..713155

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1K34_RS03500 (P1K34_03500)	-	702542..703819 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
P1K34_RS03505 (P1K34_03505)	-	703806..704981 (-)	1176	WP_010922171.1	hydroxymethylglutaryl-CoA synthase	-
P1K34_RS03510 (P1K34_03510)	-	705190..706029 (+)	840	WP_002990167.1	thymidylate synthase	-
P1K34_RS03515 (P1K34_03515)	-	706109..706606 (+)	498	WP_002984955.1	dihydrofolate reductase	-
P1K34_RS03520 (P1K34_03520)	-	706626..706796 (+)	171	WP_002990165.1	hypothetical protein	-
P1K34_RS03525 (P1K34_03525)	clpX	706926..708155 (+)	1230	WP_009880296.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
P1K34_RS03530 (P1K34_03530)	yihA	708165..708764 (+)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
P1K34_RS03535 (P1K34_03535)	-	708912..709655 (+)	744	WP_002984942.1	hypothetical protein	-
P1K34_RS03540 (P1K34_03540)	-	709714..711631 (-)	1918	Protein_650	ATP-dependent Clp protease ATP-binding subunit	-
P1K34_RS03545 (P1K34_03545)	rpiA	712013..712696 (+)	684	WP_009881270.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45020.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=800011 P1K34_RS03525 WP_009880296.1 706926..708155(+) (clpX) [Streptococcus pyogenes strain 1042]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=800011 P1K34_RS03525 WP_009880296.1 706926..708155(+) (clpX) [Streptococcus pyogenes strain 1042]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTTGAATTAGAATTTGATAA
AGCAGCTCTTGAAGCTATCGCAACTAAAGCGATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CAATGCTTGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575