Detailed information NTG0799674

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PZ486_RS06425
• Genome accession: NZ_CP119571
• Coordinates: 1248298..1249341 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain N08CSA36
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1243298..1254341

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PZ486_RS06395 (PZ486_06395)	-	1243720..1244976 (-)	1257	WP_001789555.1	aminopeptidase	-
PZ486_RS06400 (PZ486_06400)	-	1244979..1245179 (-)	201	WP_000180460.1	DUF1128 family protein	-
PZ486_RS06405 (PZ486_06405)	-	1245326..1245790 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
PZ486_RS06410 (PZ486_06410)	-	1245797..1246072 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
PZ486_RS06415 (PZ486_06415)	-	1246350..1247567 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
PZ486_RS06420 (PZ486_06420)	vraR	1247679..1248308 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
PZ486_RS06425 (PZ486_06425)	vraS	1248298..1249341 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
PZ486_RS06430 (PZ486_06430)	liaF	1249338..1250039 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
PZ486_RS06435 (PZ486_06435)	-	1250054..1250440 (-)	387	WP_001110179.1	hypothetical protein	-
PZ486_RS06440 (PZ486_06440)	map	1250657..1251415 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
PZ486_RS06445 (PZ486_06445)	-	1251827..1252813 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
PZ486_RS06450 (PZ486_06450)	-	1253244..1253657 (-)	414	WP_001670387.1	hypothetical protein	-
PZ486_RS06455 (PZ486_06455)	-	1253686..1253796 (-)	111	WP_031775032.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=799674 PZ486_RS06425 WP_001017131.1 1248298..1249341(-) (vraS) [Staphylococcus aureus strain N08CSA36]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=799674 PZ486_RS06425 WP_001017131.1 1248298..1249341(-) (vraS) [Staphylococcus aureus strain N08CSA36]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1