Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RDU00_RS04975 Genome accession   NZ_CP133449
Coordinates   961724..962368 (+) Length   214 a.a.
NCBI ID   WP_003245647.1    Uniprot ID   O07528
Organism   Bacillus subtilis strain KK195     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 956724..967368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDU00_RS04960 (RDU00_04965) glpD 956895..958562 (+) 1668 WP_003233382.1 glycerol-3-phosphate dehydrogenase -
  RDU00_RS04965 (RDU00_04970) pgcA 958694..960439 (+) 1746 WP_003244986.1 phosphoglucomutase -
  RDU00_RS04970 (RDU00_04975) yhcY 960588..961727 (+) 1140 WP_003245750.1 two-component system sensor histidine kinase YhcY -
  RDU00_RS04975 (RDU00_04980) vraR 961724..962368 (+) 645 WP_003245647.1 two-component system response regulator YhcZ Regulator
  RDU00_RS04980 (RDU00_04985) yhdA 962365..962889 (+) 525 WP_003244703.1 FMN-dependent NADPH-azoreductase -
  RDU00_RS04985 (RDU00_04990) yhdB 962904..963146 (-) 243 WP_003233373.1 YhdB family protein -
  RDU00_RS04990 (RDU00_04995) yhdC 963347..963670 (+) 324 WP_003233371.1 YqzG/YhdC family protein -
  RDU00_RS04995 (RDU00_05000) lytF 963712..965178 (-) 1467 WP_003244874.1 peptidoglycan endopeptidase LytF -
  RDU00_RS05000 (RDU00_05005) nsrR 965331..965771 (-) 441 WP_003245378.1 nitric oxide-sensing transcriptional repressor NsrR -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24022.59 Da        Isoelectric Point: 6.3034

>NTDB_id=799069 RDU00_RS04975 WP_003245647.1 961724..962368(+) (vraR) [Bacillus subtilis strain KK195]
MKIVIADDHHVVRKGLRFFFATQDDIEVVGEAATGLEALRVIEETKPDLVLMDLSMPEMDGIQAIKKAIQQFPDTNIIVL
TSYSDQEHVIPALQAGAKAYQLKDTEPEELVKTRQVHGGEYKLSTAIMPHVLTHMKNQHDPEKEKYYQLTRREKDVLTEI
ANGKSNKEIAAALFISEKTVKTHVSNLLAKLEVADRTQAALFAVKYNLNGEISK

Nucleotide


Download         Length: 645 bp        

>NTDB_id=799069 RDU00_RS04975 WP_003245647.1 961724..962368(+) (vraR) [Bacillus subtilis strain KK195]
ATGAAAATTGTCATTGCTGATGATCATCATGTTGTCAGAAAGGGTCTGCGTTTTTTCTTTGCCACCCAGGATGATATTGA
AGTCGTCGGAGAAGCTGCAACTGGATTAGAAGCCCTCCGTGTCATCGAAGAGACAAAGCCGGATCTTGTGCTAATGGATT
TGTCTATGCCCGAGATGGACGGCATTCAAGCCATTAAAAAAGCAATACAGCAATTTCCGGATACGAATATCATTGTGCTG
ACGAGCTACTCTGATCAGGAGCACGTCATCCCCGCGCTTCAGGCAGGCGCGAAGGCGTATCAATTAAAGGATACGGAGCC
CGAGGAATTGGTGAAAACACGACAAGTGCATGGTGGCGAATACAAGCTTTCTACAGCTATTATGCCCCATGTGCTGACAC
ATATGAAAAATCAGCACGACCCGGAAAAAGAAAAATACTATCAATTAACTAGAAGGGAAAAAGACGTTCTGACTGAAATA
GCGAACGGGAAAAGCAATAAAGAAATCGCAGCAGCCTTGTTTATTTCAGAAAAAACAGTAAAAACCCATGTATCGAATCT
TTTAGCAAAACTTGAAGTGGCCGATCGCACGCAAGCAGCGCTTTTCGCAGTGAAATATAACCTGAATGGAGAGATCTCAA
AATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O07528

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

97.664

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

38.428

100

0.411